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Relationships of Lipids Profile with Health-Related Quality of Life in Chinese Centenarians

  • Published:
The journal of nutrition, health & aging

Abstract

Objectives

With the acceleration of the process of aging population, to enjoy a higher health-related quality of life (HRQoL) is the goal of the elderly population and public health. Studies on relationship between HRQoL and lipid profile through a large sample of representative elderly population are scare.

Objective

This study was conducted to firstly explore the relationships of lipid profile with HRQoL in Chinese centenarian population.

Participants

A complete sample of 1002 participants aged over 100 years from Hainan province were recruited in the current study.

Main measure

Questionnaire investigation, physical examination and blood specimen collection were carried out by family survey. The EuroQol-5 Dimensions(EQ-5D, and EQ-VAS were used to assess HRQoL.

Results

In multivariate linear regression analyses, a significant association was found between EQ-5D and lipid profile, including total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), and similar association was also existed between EQ-VAS and TC, LDL-C HDL-C, after adjustment. The score of EQ-5D and EQ-VAS in male centenarian was higher than that of the female centenarian.

Conclusion

Lipid profile was positively associated with the HRQoL in Chinese centenarians.

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Acknowledgments

All authors thank staff who participated in the field survey and centenarians in CHCCS. This study was financed by Beijing Nova Program (Z181100006218085), Opening Foundation of State Key Laboratory of Kidney Diseases (KF-01-115), Opening Foundation of National Clinical Research Center of Geriatrics (NCRCG-PLAGH-2017017), National Natural Science Foundation of China (81773502, 81703285, 81703308), Medical Big Data Fund of Chinese PLA General Hospital (2018MBD-029).

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Authors and Affiliations

  1. Institute of Geriatrics, the 2nd medical center, Beijing Key Laboratory of Aging and Geriatrics, National Clinical Research Center for Geriatrics Diseases, Chinese People’s Liberation Army General Hospital, Beijing, 100853, China

    S. Wang, S. Yang, W. Jia, W. Cao, K. Han, Miao Liu & Y. He

  2. State Key Laboratory of Kidney Diseases, Chinese People’s Liberation Army General Hospital, Beijing, 100853, China

    Miao Liu & Y. He

  3. 28 Fuxing Road, Haidian District, Beijing, 100853, China

    Miao Liu & Y. He

Authors
  1. S. Wang
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  2. S. Yang
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  3. W. Jia
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  4. W. Cao
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  5. K. Han
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  6. Miao Liu
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  7. Y. He
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Corresponding authors

Correspondence to Miao Liu or Y. He.

Ethics declarations

Ethical Standards: This study has been approved by the Ethics Committee of the Hainan Branch of the Chinese People’s Liberation Army General Hospital (Sanya, Hainan; Number: 301hn11201601). All the centenarians were informed about the purposes of the study and consequently have signed their “consent of the patient”. All investigations conformed to the principles outlined in the Declaration of Helsinki.

Conflict of interest: All authors have no conflicts of interest in this work.

Financial disclosure: All authors have no financial disclosures.

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These two authors are co-first authors

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Cite this article

Wang, S., Yang, S., Jia, W. et al. Relationships of Lipids Profile with Health-Related Quality of Life in Chinese Centenarians. J Nutr Health Aging 24, 404–411 (2020). https://doi.org/10.1007/s12603-020-1340-5

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  • DOI: https://doi.org/10.1007/s12603-020-1340-5

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