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Solitary extramedullary plasmacytoma of the rectum complicating ulcerative colitis

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Abstract

Solitary extramedullary plasmacytoma (EMP) arising in the rectum is an extremely rare clinical entity. Only ten cases have been reported in the English-language literature. We experienced a case of an EMP in the rectum of a 55-year-old man with an 8-year history of proctitis-type ulcerative colitis (UC). The plasmacytoma appeared as an 8-mm semipedunculated polypoid lesion in the actively inflamed rectal mucosa when the remittent UC flared. The tumor was treated using endoscopic mucosal resection. This is the second case of rectal EMP associated with UC after a similar report was published in 2004. Both patients had a chronic history of proctitis-type UC and were taking no immunosuppressive agents that could cause Epstein–Barr virus-associated plasmacytoma, such as thiopurines. The UC activity seemed to correspond well with the development of the rectal EMP. Therefore, we herein discuss a possible association between rectal EMP and UC and review the past literature of rectal EMP.

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Authors and Affiliations

  1. Division of Internal Medicine, Hiratsuka Gastroenterological Hospital, 3-2-16 Nishiikebukuro, Toshima-ku, Tokyo, 171-0021, Japan

    Wataru Miwa, Takashi Hiratsuka & Shutetsu Tei

  2. Division of Surgery, Hiratsuka Gastroenterological Hospital, Tokyo, Japan

    Ken Sato

  3. Department of Pathology, Nikko Medical Center, Dokkyo Medical University, Tochigi, Japan

    Kato Yo

Authors
  1. Wataru Miwa
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  2. Takashi Hiratsuka
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  3. Shutetsu Tei
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  4. Ken Sato
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  5. Kato Yo
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Correspondence to Wataru Miwa.

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Wataru Miwa, Takashi Hiratsuka, Shutetsu Tei, Ken Sato, Yo Kato declare that they have no conflict of interest.

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All procedures followed have been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments.

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Informed consent was obtained from all patients for being included in the study.

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Miwa, W., Hiratsuka, T., Tei, S. et al. Solitary extramedullary plasmacytoma of the rectum complicating ulcerative colitis. Clin J Gastroenterol 12, 160–165 (2019). https://doi.org/10.1007/s12328-018-0907-8

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  • DOI: https://doi.org/10.1007/s12328-018-0907-8

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