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L’adénome métanéphrique bilatéral du rein

Bilateral renal metanephric adenoma

  • Cas Clinique
  • Published:
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Resume

L’adénome métanéphrique du rein est une tumeur épithéliale bénigne rare. Son diagnostic est exclusivement histologique. Le diagnostic différentiel se fait essentiellement avec le néphroblastome et le carcinome papillaire à cellules rénales. L’étude cytogénétique apporte des éléments importants pour différencier entre ces trois entités histologiques. L’adénome métanéphrique bilatéral est exceptionnel (pour autant que nous sachions un seul cas a été rapporté dans la littérature) et pose un problème de diagnostic différentiel avec le cancer rénal bilatéral. Nous rapportons une nouvelle observation de cette affection rare chez un patient âgé de 64 ans.

Abstract

Renal metanephric adenoma is an uncommon benign epithelial neoplasm. The diagnosis is exclusively histological. Differential diagnosis essentially includes Wilms’ tumor and papillary renal cell carcinoma. Cytogenetic analysis seems to be important for distinguishing these three histological entities. Bilateral metanephric adenoma of the kidney is an exceptional entity (to our knowledge only one case has been reported in the literature) which renders the differential diagnosis with bilateral cancer of the kidney difficult. We report a new case seen in a 64-year-old patient.

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Bibliographie

  1. Stambolis C. Benign epithelial nephroblastoma. A contribution to its histogenesis. Virchows Arch.A Pathol. Anat.Histol. 1977; Nov 25;376(3):267–272.

    Article  PubMed  CAS  Google Scholar 

  2. Syrjanen KJ. Renal adenomatosis. Report of an autopsy case. Scand.J.Urol.Nephrol. 1979;13(3):329–334.

    Article  Google Scholar 

  3. Amie F, Andre D, Foulet Roge A, Goura E, Chautard D, Colombel P. Adénome métanephrique bilatéral du rein. [Bilateral renal metanephric adenoma]. Prog.Urol. 2004; Sep;14(4):534,7; discussion 537.

    PubMed  Google Scholar 

  4. Tosaka A, Ohya K, Yamada K, Ohashi H, Kitahara S, Sekine H, et al. Incidence and properties of renal masses and asymptomatic renal cell carcinoma detected by abdominal ultrasonography. J.Urol. 1990; Nov;144(5):1097–1099.

    PubMed  CAS  Google Scholar 

  5. Martin L, Justrabo E, Michel F, Billerey C, Yaziji N. L’adénome métanephrique du rein. Une étude anatomoclinique, immunohistochimique et ultrastructurale de deux cas. Metanephric adenoma of the kidney. A clinicopathologic, immunohistochemical and electron microscopic study of two cases]. Ann. Pathol. 1998; Apr;18(2):120–124.

    PubMed  CAS  Google Scholar 

  6. Lallemand B, Dumont O, Pontus T. Hématome péri-rénal spontané causé par un adénome rénal. [Spontaneous perirenal haematoma caused by a renal adenoma]. Prog. Urol. 2002; Jun;12(3):474–476.

    PubMed  Google Scholar 

  7. Fleming S. Classification of renal epithelial neoplasms. Curr.Diagnos.Pathol. 2000; Mar;6(1):38–44.

    Article  Google Scholar 

  8. Barriol D, Lechevallier E, Andre M, Daniel L, Ortega JC, Rossi D, et al. Les biopsies percutanées à l’aiguille fine des tumeurs solides du rein sous guidage tomodensitométrique. [CT-guided percutaneous fine needle biopsy of solid tumors of the kidney]. Prog.Urol. 2000; Dec;10(6):1145–1151.

    PubMed  CAS  Google Scholar 

  9. Kato H, Suzuki M, Aizawa S, Hano H. Metanephric adenoma of the kidney with massive hemorrhage and necrosis: Immunohistochemical, ultrastructural and flow cytometric studies. Int.J.Surg.Pathol. 2003; Oct;11(4):345–352.

    Article  PubMed  Google Scholar 

  10. Nagashima Y, Inayama Y, Kato Y, Sakai N, Kanno H, Aoki I, et al. Pathological and molecular biological aspects of the renal epithelial neoplasms, up-to-date. Pathol.Int. 2004; Jun;54(6):377–386.

    Article  PubMed  Google Scholar 

  11. Lindner V, Lang H, Jacqmin D. Pathology and genetics in renal cell cancer. EAU Update Series. 2003; Dec;1(4):197–208.

    Article  Google Scholar 

  12. Rakheja D, Lian F, Tomlinson GE, Ewalt DH, Schultz RA, Margraf LR. Renal metanephric adenoma with previously unreported cytogenetic abnormalities: Case report and review of the literature. Pediatr.Dev.Pathol. 2005; Mar–Apr;8(2):218–223.

    Article  PubMed  Google Scholar 

  13. Brunelli M, Eble JN, Zhang S, Martignoni G, Cheng L. Metanephric adenoma lacks the gains of chromosomes 7 and 17 and loss of Y that are typical of papillary renal cell carcinoma and papillary adenoma. Mod.Pathol. 2003; Oct;16(10):1060–1063.

    Article  PubMed  Google Scholar 

  14. Lerut E, Roskams T, Joniau S, Oyen R, Achten R, Van Poppel H, et al. Metanephric adenoma during pregnancy: Clinical presentation, histology and cytogenetics. Hum. Pathol. 2006; Sep;37(9):1227–1232.

    Article  PubMed  Google Scholar 

  15. Arroyo MR, Green DM, Perlman EJ, Beckwith JB, Argani P. The spectrum of metanephric adenofibroma and related lesions: Clinicopathologic study of 25 cases from the National Wilms Tumor Study Group Pathology Center. Am.J.Surg.Pathol. 2001; Apr;25(4):433–444.

    Article  PubMed  CAS  Google Scholar 

  16. Davis CJ,Jr, Barton JH, Sesterhenn IA, Mostofi FK. Metanephric adenoma. Clinicopathological study of fifty patients. Am.J.Surg.Pathol. 1995; Oct;19(10):1101–1114.

    Article  PubMed  Google Scholar 

  17. Drut R, Drut RM, Ortolani C. Metastatic metanephric adenoma with foci of papillary carcinoma in a child: A combined histologic, immunohistochemical and FISH study. Int.J.Surg.Pathol. 2001; Jul;9(3):241–247.

    Article  PubMed  CAS  Google Scholar 

  18. Renshaw AA, Freyer DR, Hammers YA. Metastatic metanephric adenoma in a child. Am.J.Surg.Pathol. 2000; Apr;24(4):570–574.

    Article  PubMed  CAS  Google Scholar 

  19. Hes O, Curik R, Malatkova V, Mainer K, Michal M. Metanephric adenoma and papillary carcinoma with sarcomatoid dedifferentiation of kidney. A case report. Pathol.Res.Pract. 2003;199(9):629–632.

    Article  PubMed  Google Scholar 

  20. Picken MM, Curry JL, Lindgren V, Clark JI, Eble JN. Metanephric adenosarcoma in a young adult: Morphologic, immunophenotypic, ultrastructural and fluorescence in situ hybridization analyses: A case report and review of the literature. Am.J.Surg.Pathol. 2001; Nov;25(11):1451–1457.

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Service d’urologie, Hôpital Militaire d’Instruction Mohammed V, Rabat, Maroc

    Abdelghani Ammani, M. Ghadouane, A. Janane, J. Sossa, A. Ameur & M. Abbar

  2. N0.772, Hay el manzah C.Y.M, Rabat, Maroc

    Abdelghani Ammani

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  1. Abdelghani Ammani
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  2. M. Ghadouane
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  3. A. Janane
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  4. J. Sossa
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  5. A. Ameur
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  6. M. Abbar
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Correspondence to Abdelghani Ammani.

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Ammani, A., Ghadouane, M., Janane, A. et al. L’adénome métanéphrique bilatéral du rein. Afr J Urol 15, 143–147 (2009). https://doi.org/10.1007/s12301-009-0017-4

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  • DOI: https://doi.org/10.1007/s12301-009-0017-4

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