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Summary and Review of the Abstracts on Hemostasis/Thrombosis Presented at Haematocon 2018, Kochi

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Abstract

The hemostatic pathways involve a complex interplay of a vast array of inherited and acquired factors. Derangements of these pathways lead to several disorders that are complex and challenging not just for laboratory and clinical hematologists but also of concern to public health officials and policy makers. The past decade has seen an increased focus on research in this area with several recent meetings focusing on the diagnosis and management of persons afflicted with these disorders. Haematocon 2018 is the national conference of the Indian Society of Haematology and Blood Transfusion, and papers presented at this year’s event offered a glimpse of the contemporary research efforts in India. This mini-review summarizes and places in perspective, salient results from this meeting. The papers are divided into broad subsections of hemophilia, rare clotting factor deficiencies, platelet function defects, macrothrombocytopenia syndromes, thromboelastography, inherited and acquired prothrombotic states, and finally a miscellaneous section. Relevant recent Indian publications on the theme are also discussed.

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References

  1. Yadav T, Singh S, Singh J et al (2018) Demographic profile and real world data of persons with haemophilia (PWH) in a resource constrained setup. Indian J Hematol Blood Transfus 34(Suppl 1):S137

    Google Scholar 

  2. Chakraborty J, Bhattacharyya M, Ray SS (2018) Effect of low dose prophylaxis versus episodic treatment on joint events in severe hemophilia A patients above 2 years: a randomized open label pilot study in eastern India. Indian J Hematol Blood Transfus 34(Suppl 1):S68

    Google Scholar 

  3. Yadav N, Sharma S, Satyanand K et al (2018) Low dose secondary and tertiary prophylaxis in severe hemophilia A reduces bleeding rates. Indian J Hematol Blood Transfus 34(Suppl 1):S134

    Google Scholar 

  4. Kolla R, Brand-Stauffer B, Dahl PW et al (2018) Turoctocog alfa is stable during storage at 40°C and multiple sequences of temperature cycling. Indian J Hematol Blood Transfus 34(Suppl 1):S125

    Google Scholar 

  5. Joshi AD, Kannan S, Patel D et al (2018) Pharmacokinetic study of factor infusion in haemophilia Aand B patients who underwent surgery: a single centre experience from western India. Indian J Hematol Blood Transfus 34(Suppl 1):S143

    Google Scholar 

  6. Patil R, Shetty S (2018) Simple aPTT based tests for differential diagnosis of haemophilia B and B—preliminary results. Indian J Hematol Blood Transfus 34(Suppl 1):S24

    Google Scholar 

  7. Maddali M, Venkatesan RS, Govindanattar SD et al (2018) A long amplicon PCR-next generation sequencing (LAP-NGS) method for efficient and cost—effective molecular diagnosis of haemophilia A and haemophilia B. Indian J Hematol Blood Transfus 34(Suppl 1):S25

    Google Scholar 

  8. Sankari DG, Rajkumar SV, Fouzia NA et al (2018) Duplication in factor 8 gene leads to abnormal pattern in intron 22 inversion analysis. Indian J Hematol Blood Transfus 34(Suppl 1):S139

    Google Scholar 

  9. Ghosh K (2018) Evolution of hemophilia care in India. Indian J Hematol Blood Transfus. https://doi.org/10.1007/s12288-018-1059-1

    Article  PubMed  PubMed Central  Google Scholar 

  10. Ramakrishnan K, Shantha K, Ahammad J et al (2018) Combined factor V and VIII deficiency: case report of an unique entity among hemostatic disorders. Indian J Hematol Blood Transfus 34(Suppl 1):S130

    Google Scholar 

  11. Suman F, Siddique F, Gayathri S et al (2018) Heterogeneous clinical presentation of factor VII deficiency in a family. Indian J Hematol Blood Transfus 34(Suppl 1):S132

    Google Scholar 

  12. Chandra D, Gupta R, Rahman K et al (2018) Glanzmann thrombasthenia: clinico-pathological spectrum of a rare disease. Indian J Hematol Blood Transfus 34(Suppl 1):S135

    Google Scholar 

  13. Ahammad J, Kurien A, Shastry S et al (2018) Utility of thromboelastography in the diagnosis of Glanzmann’s thrombasthenia. Indian J Hematol Blood Transfus 34(Suppl 1):S167

    Google Scholar 

  14. Shanbhag S, Soni P, Deshpande R et al (2018) Unusual clinical and laboratory indicators in two cases leading to the diagnosis of Glanzmanns thrombasthenia (GT). Indian J Hematol Blood Transfus 34(Suppl 1):S138

    Google Scholar 

  15. Sultan N, Sharma SK (2018) Prevalence of low platelet count and identification of associating determinants and genetic polymorphism in healthy individuals of upper Assam, India. Indian J Hematol Blood Transfus. https://doi.org/10.1007/s12288-018-1007-0

    Article  PubMed  Google Scholar 

  16. Patel P, Shah A, Mishra K et al (2018) Prevalence of macrothrombocytopenia in healthy college students in western India. Indian J Hematol Blood Transfus 99:100–101. https://doi.org/10.1007/s12288-018-0970-9

    Article  Google Scholar 

  17. Ghosh K, Bhattacharya M, Chowdhury R et al (2018) Inherited macrothrombocytopenia: correlating morphology, epidemiology, molecular pathology and clinical features. Indian J Hematol Blood Transfus 34:387. https://doi.org/10.1007/s12288-018-0950-0

    Article  PubMed  PubMed Central  Google Scholar 

  18. Kafley P, Nair SC, Ramya V (2018) Clinical utility of ISTH bleeding assessment tool and thromboelastography (TEG) in assessment of patients referred for evaluation of bleeding disorders. Indian J Hematol Blood Transfus 34(Suppl 1):S69

    Google Scholar 

  19. Subramanian S, Albert V, Agrawal D et al (2018) Can thromboelastography (TEG) be used to assess platelet transfusion response in isolated severe TBI patients? Indian J Hematol Blood Transfus 34(Suppl 1):S69

    Google Scholar 

  20. Mohan G, Ahammad J, Shastry S (2018) Analyzing the efficacy of laboratory investigations to identify hemostatic abnormalities in massive blood transfusion. Indian J Hematol Blood Transfus 34(Suppl 1):S186

    Google Scholar 

  21. David S, Kulkarni U, Vijayan R et al (2018) Thromboelastometry as a tool to assess the haemostatic risk of coagulopathy in acute promyelocytic leukemia. Indian J Hematol Blood Transfus 34(Suppl 1):S276

    Google Scholar 

  22. Kumar N, Ahluwalia J, Das R et al (2018) Hereditary and acquired thrombophilia in pediatric cases of splanchnic vein thrombosis. Indian J Hematol Blood Transfus 34(Suppl 1):S152

    Google Scholar 

  23. Kishor K, Sharma A, Pandey HR et al (2018) Influence of tissue factor promoter polymorphism on risk of deep vein thrombosis. Indian J Hematol Blood Transfus 34(Suppl 1):S150

    Google Scholar 

  24. Sharma A, Ranjan R, Kishor K et al (2018) HR2 haplotype and Arg485Lys polymorphisms: association with FV levels, APC ratio and their role in the development of DVT. Indian J Hematol Blood Transfus 34(Suppl 1):S148

    Google Scholar 

  25. Maru P, Sharma S, Kotru M et al (2018) Paraoxonase 2 gene polymorphism in patients with coronary artery disease. Indian J Hematol Blood Transfus 34(Suppl 1):S220

    Google Scholar 

  26. Ranjan R, Sharma A, Kumar S et al (2018) Screening of factor XIII Val34Leu polymorphism for identifying it’s role in Indian myocardial infarction patients. Indian J Hematol Blood Transfus 34(Suppl 1):S127

    Google Scholar 

  27. Vishwajeet V, Jamwal M, Sharma P et al (2018) Coagulation F13A1 V34L, fibrinogen and homocysteine versus conventional risk factors in the pathogenesis of MI in young persons. Acta Cardiol 73:328–334

    Article  PubMed  Google Scholar 

  28. Sikka M, Sinha P, Sharma S et al (2018) Activated protein C resistance in Indian women with recurrent fetal loss. Indian J Hematol Blood Transfus 34(Suppl 1):S151

    Google Scholar 

  29. Sharma I, Sikka M, Kotru M et al (2018) Prevalence of thrombophilic risk factors in patients with SLE. Indian J Hematol Blood Transfus 34(Suppl 1):S149

    Google Scholar 

  30. Venkatesh D, Ambika PL, Ramraj A et al (2018) Lupus anticoagulant testing—experience from tertiary care center in south India. Indian J Hematol Blood Transfus 34(Suppl 1):S147

    Google Scholar 

  31. Murari M, Misra RN (2018) Lupus anticoagulant (LA) and anticardiolipin antibodies (ACL) in patients of SLE presenting with thrombosis and/or foetal loss. Indian J Hematol Blood Transfus 34(Suppl 1):S145

    Google Scholar 

  32. Vimal M, Sharma S, Sharma S (2018) Study of vitamin B12, folate and homocysteine levels in children with ischemic stroke. Indian J Hematol Blood Transfus 34(Suppl 1):S146

    Google Scholar 

  33. Bhattacharya R, Lakshmi S, Laxminarayana K (2018) JAK-2 mutation: predictor of both thrombotic and hemorrhagic events in myeloproliferative neoplasia? Indian J Hematol Blood Transfus 34(Suppl 1):S324

    Google Scholar 

  34. Tiwari NR, Chaudhari K, Deshmukh S et al (2018) Paroxysmal nocturnal hemoglobinuria, an elusive diagnosis. Indian J Hematol Blood Transfus 34(Suppl 1):S107

    Google Scholar 

  35. Chaudhury A, Balakrishnan A, Thai C et al (2018) The efficacy and safety of rivaroxaban and dalteparin in the treatment of cancer associated venous thrombosis. Indian J Hematol Blood Transfus 34:530. https://doi.org/10.1007/s12288-017-0895-8

    Article  PubMed  Google Scholar 

  36. Ganguli P, Singh SP, Ahmed R et al (2018) Microparticles: an initiator of thrombosis: the 17,700 feet experiment. Indian J Hematol Blood Transfus 34(Suppl 1):S74

    Google Scholar 

  37. Yanamandra U, Bhattachar SA, Das SK et al (2018) Hematological Parameters in Native Highlanders of Ladakh Aged 4–19 Years. Indian J Hematol Blood Transfus 34:731. https://doi.org/10.1007/s12288-018-0967-4

    Article  PubMed  Google Scholar 

  38. Paulose RM, Neufeld EJ, Benchikh S et al (2018) Recombinant activated factor VII: 20-year safety update including > 5 million administered doses. Indian J Hematol Blood Transfus 34(Suppl 1):S129

    Google Scholar 

  39. Tiwari NR, Chaudhari K, Sharma V (2018) Acquired hemophilia a in large granular lymphocytic leukemia. Indian J Hematol Blood Transfus 34(Suppl 1):S319

    Google Scholar 

  40. Kumar N, Rajpal S, Ahluwalia J et al (2018) Acquired hemophilia A: experience of a tertiary care institute from North India. Indian J Hematol Blood Transfus 34:524. https://doi.org/10.1007/s12288-017-0873-1

    Article  PubMed  Google Scholar 

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  1. Department of Hematology, Postgraduate Institute of Medical Education and Research, Level 5, Research Block A, Sector 12, Chandigarh, 160012, India

    Prashant Sharma

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  1. Prashant Sharma
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Sharma, P. Summary and Review of the Abstracts on Hemostasis/Thrombosis Presented at Haematocon 2018, Kochi. Indian J Hematol Blood Transfus 35, 32–36 (2019). https://doi.org/10.1007/s12288-019-01076-y

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  • DOI: https://doi.org/10.1007/s12288-019-01076-y

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