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Electrochemical Sensor based on Imprinted Sol-Gel Polymer on Au NPs-MWCNTs-CS Modified Electrode for the Determination of Acrylamide

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Abstract

A sensitive molecularly imprinted electrochemical sensor was successfully constructed for the detection of acrylamide (AM). It is based on a glassy carbon electrode modified with a composites prepared from gold nanoparticles, multiwalled carbon nanotubes, and chitosan along with a sol-gel-based molecularly imprinted polymer (MIP) film. The latter was prepared using AM as the template molecule, 3-aminopropyltrimethoxysilane as the functional monomer, and tetraethoxysilane as the cross-linker. The MIP sensor showed a linear current response to the target AM concentration in the range from 0.05 to 5 μg mL−1 at a working voltage of 0–0.4 V with a lower detection limit of 0.028 μg mL−1 (S/N = 3). It was successfully applied to the detection of AM in potato chips. HPLC analysis was also conducted to detect AM in the same samples to demonstrate the applicability of the electrochemical MIP sensor.

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Acknowledgments

This work was financially supported by the National Natural Science Foundation of China (No. 31201375), Hunan Provincial Natural Science Foundation of China (No. 2015JJ3077), and Special Fund for Agro-scientific Research in the Public Interest (No. 201303084).

Compliance with Ethics Requirements

This article does not contain any studies with human or animal subjects.

Conflict of Interest

Xia Liu declares that she has no conflict of interest. Lu-Gang Mao declares that he has no conflict of interest. Yuan-Liang Wang declares that he has no conflict of interest. Xing-Bo Shi declares that he has no conflict of interest. Yan Liu declares that she has no conflict of interest. Yang Yang declares that she has no conflict of interest. Zao He declares that she has no conflict of interest.

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Authors and Affiliations

  1. College of Food Science and Technology, Hunan Agricultural University, Hunan Province Key Laboratory of Food Science and Biotechnology, Changsha, 410128, People’s Republic of China

    Xia Liu, Lu-Gang Mao, Yuan-Liang Wang, Xing-Bo Shi, Yan Liu, Yang Yang & Zao He

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  1. Xia Liu
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  2. Lu-Gang Mao
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  3. Yuan-Liang Wang
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  4. Xing-Bo Shi
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  5. Yan Liu
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  7. Zao He
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Correspondence to Xia Liu.

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Liu, X., Mao, LG., Wang, YL. et al. Electrochemical Sensor based on Imprinted Sol-Gel Polymer on Au NPs-MWCNTs-CS Modified Electrode for the Determination of Acrylamide. Food Anal. Methods 9, 114–121 (2016). https://doi.org/10.1007/s12161-015-0172-0

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  • DOI: https://doi.org/10.1007/s12161-015-0172-0

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