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Spindle Cell Epulis in an 8-Month-Old Child: A Histologic Variant of Congenital Granular Cell Epulis?

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Abstract

A case of an epulis in an 8-month-old boy is reported. The tumor was localized on the mandibular alveolar ridge and, according to the parents, was a recurrence of a congenital tumor excised when the boy was 2 months old. Microscopically, it was composed of many spindled or ovoid cells with vesicular nuclei and non-granular eosinophilic cytoplasm, and covered by acanthotic parakeratinized squamous epithelium with broad rete pegs. Immunohistochemically, the spindled and ovoid cells were intensely positive for vimentin and neuron-specific enolase, and negative for S-100 protein. The final diagnosis was spindle cell epulis. The possible correlation of this lesion with congenital granular cell epulis is discussed.

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Acknowledgments

The expert technical assistance of Mr. Georgios Babaliaris is acknowledged.

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Authors and Affiliations

  1. 6-7 Poseidonos street, Athens, 17561, Greece

    Andreas-Christoforos Prigkos, Michail D. Nikolakis & Vasileios F. Kyriakopoulos

  2. Department of Oral Pathology, Dental School, University of Athens, 2 Thivon street, 11527, Athens, Greece

    Konstantinos I. Tosios

Authors
  1. Andreas-Christoforos Prigkos
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  2. Michail D. Nikolakis
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  3. Vasileios F. Kyriakopoulos
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  4. Konstantinos I. Tosios
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Correspondence to Konstantinos I. Tosios.

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Prigkos, AC., Nikolakis, M.D., Kyriakopoulos, V.F. et al. Spindle Cell Epulis in an 8-Month-Old Child: A Histologic Variant of Congenital Granular Cell Epulis?. Head and Neck Pathol 6, 467–470 (2012). https://doi.org/10.1007/s12105-012-0351-x

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  • DOI: https://doi.org/10.1007/s12105-012-0351-x

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