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Effects of the Oral Administration of K2Cr2O7 and Na2SeO3 on Ca, Mg, Mn, Fe, Cu, and Zn Contents in the Heart, Liver, Spleen, and Kidney of Chickens

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Abstract

This study aimed to investigate the effects of selenium on the ion profiles in the heart, liver, spleen, and kidney through the oral administration of hexavalent chromium. Approximately 22.14 mg/kg b.w. K2Cr2O7 was added to water to establish a chronic poisoning model. Different selenium levels (0.00, 0.31, 0.63, 1.25, 2.50, and 5.00 mg Na2SeO3/kg b.w.) around the safe dose were administered to the experimental group model. Ca, Mg, Mn, Fe, Cu, and Zn were detected in the organs through flame atomic absorption spectrometry after these organs were exposed to K2Cr2O7 and Na2SeO3 for 14, 28, and 42 days. Results showed that these elements exhibited various changes. Ca contents declined in the heart, liver, and spleen. Ca contents also decreased on the 28th day and increased on the 42nd day in the kidney. Mn contents declined in the heart and spleen but increased in the kidney. Mn contents also decreased on the 28th day and increased on the 42nd day in the liver. Cu contents declined in the heart and spleen. Cu contents increased on the 28th day and decreased on the 42nd day in the liver and kidney. Zn contents declined in the heart and spleen. Zn contents increased on the 28th day and decreased on the 42nd day in the liver and kidney. Fe contents decreased in the heart and liver. Fe contents increased on the 28th day and decreased on the 42nd day in the spleen and kidney. Mg contents did not significantly change in these organs. Appropriate selenium contents enhanced Mn and Zn contents, which were declined by chromium. Conversely, appropriate selenium contents reduced Ca, Fe, and Cu contents, which were increased by chromium. In conclusion, the exposure of chickens to K2Cr2O7 induced changes in different trace elements, and Na2SeO3 supplementation could alleviate this condition.

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Acknowledgements

This work was supported by the National Key R&D Program (2016YFD0501208) and the Shandong Modern Agricultural Technology & Industry System (No. SDAIT-11-04).

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Authors and Affiliations

  1. College of Veterinary Medicine, Research Center for Animal Disease Control Engineering, Shandong Agricultural University, Tai’an, Shandong Province, 271018, China

    Peng Chen, Yiran Zhu, Huiyu Wan, Yang Wang, Pan Hao, Ziqiang Cheng, Yongxia Liu & Jianzhu Liu

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  1. Peng Chen
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  2. Yiran Zhu
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  3. Huiyu Wan
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  4. Yang Wang
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  8. Jianzhu Liu
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Correspondence to Jianzhu Liu.

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Chen, P., Zhu, Y., Wan, H. et al. Effects of the Oral Administration of K2Cr2O7 and Na2SeO3 on Ca, Mg, Mn, Fe, Cu, and Zn Contents in the Heart, Liver, Spleen, and Kidney of Chickens. Biol Trace Elem Res 180, 285–296 (2017). https://doi.org/10.1007/s12011-017-0999-x

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