Abstract
Background
Patients with skeletal dysplasia are prone to degenerative hip disease thus requiring THA at a younger age than the general population. This is a technically demanding procedure with high complication and revision rates. Achieving good femoral fixation can be challenging because of the abnormal features of the hip.
Questions/purposes
We therefore determined: (1) survivorship, (2) function, (3) radiographic findings, and (4) complications associated with a cementless custom-made femoral component used in THAs for patients with skeletal dysplasia and compared these parameters with those from other types of femoral fixation.
Patients and Methods
Between 1992 and 2005, 40 THAs were performed in 25 patients with skeletal dysplasia using custom-made cementless femoral components. There were 15 men and 10 women with a mean age of 37.5 years (range, 18–61 years) and a mean height of 145 cm (range, 120–173 cm). Patients were followed clinically and radiographically for a minimum of 4.3 years (mean, 10.1 years; range, 4.3–18.2 years).
Results
The survivorship rates for the femoral and acetabular components were 92% and 70%, respectively, at 220 months. Revision arthroplasty was performed in four of 40 hips (10%). In two, the acetabular component was revised for aseptic loosening, one had both components revised for aseptic loosening, and one had an isolated femoral component revision for deep infection. The mean Harris hip score improved from 41 (range, 27–57) preoperatively to 80 (range, 51–94) at final followup. There were two intraoperative proximal femoral fractures and one dislocation.
Conclusions
When compared with studies with equal followup, custom-made cementless components in THAs for patients with skeletal dysplasia apparently had lower revision and complication rates with comparable function and higher midterm survival.
Level of Evidence
Level IV, therapeutic study. See Guidelines for Authors for a complete description of levels of evidence.
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Acknowledgments
We acknowledge Professor P. S. Walker from the Biomedical Engineering Department of University College London for his pioneering work on developing CAD-CAM custom-made orthopaedic implants. We also acknowledge the contribution of Professor G. Bentley, Stanmore Implants Worldwide Ltd, and Professor G. W. Blunn and Dr J. Hua from the Institute of Orthopaedics & Musculoskeletal Science, University College London.
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Each author certifies that he or she has no commercial associations (eg, consultancies, stock ownership, equity interest, patent/licensing arrangements, etc) that might pose a conflict of interest in connection with the submitted article.
Each author certifies that his or her institution approved the human protocol for this investigation, that all investigations were conducted in conformity with ethical principles of research, and that informed consent for participation in the study was obtained.
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Sewell, M.D., Hanna, S.A., Muirhead-Allwood, S.K. et al. Custom Cementless THA in Patients with Skeletal Dysplasia Results in Lower Apparent Revision Rates than Other Types of Femoral Fixation. Clin Orthop Relat Res 469, 1406–1412 (2011). https://doi.org/10.1007/s11999-010-1656-2
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DOI: https://doi.org/10.1007/s11999-010-1656-2