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Migraine: What Imaging Reveals

  • Neuroimaging (DJ Brooks, Section Editor)
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Abstract

Although migraine symptomatology is well-defined, our understanding of migraine pathophysiology is incomplete. Structural and functional brain imaging can contribute to a greater understanding of migraine pathophysiology. Recent neuroimaging studies demonstrate that migraine is associated with structural and functional alterations of brain regions commonly implicated in pain processing. This review summarizes recent brain structural and functional imaging findings in migraine and highlights those that are associated with characteristics such as the presence or absence of aura, associated cognitive dysfunction, sex-differences (male vs. female migraineurs), age, and disease burden.

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  1. Mayo Clinic, 5777 East Mayo Boulevard, Phoenix, AZ, 85054, USA

    Catherine D. Chong, Todd J. Schwedt & David W. Dodick

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  1. Catherine D. Chong
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Correspondence to Catherine D. Chong.

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Conflict of Interest

Catherine D. Chong declares that she has no conflict of interest.

Todd J. Schwedt has received consulting fees from Allergan, Amgen, Dr. Reddy’s, GBS, Supernus, Teva, and Zogenix. He receives royalties from Cambridge University Press and UpToDate .

David  W. Dodick, MD, in the past 12 months, has served on advisory boards and has consulted for Allergan, Amgen, Alder, CoLucid, Dr Reddy’s, Merck, ENeura, Eli Lilly & Company, Autonomic Technologies, Teva, Xenen, Tonix, Trigemina, Supernus, ScionNeurostim, and Boston Scientific. He has options in Xalan, Epien, and Second Opinion. He is on the board of directors of the King Devick Test. Within the past 12 months, Dr. Dodick has received royalties, funding for travel, speaking, or editorial activities from the following: Healthlogix, Haymarket Media Group, Ltd., SAGE Publishing, Lippincott Williams & Wilkins, Oxford University Press, and Cambridge University Press. He receives publishing royalties for Wolff’s Headache, 8th edition (Oxford University Press, 2009) and Handbook of Headache (Cambridge University Press, 2010). 

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This article is part of the Topical collection on Neuroimaging

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Chong, C.D., Schwedt, T.J. & Dodick, D.W. Migraine: What Imaging Reveals. Curr Neurol Neurosci Rep 16, 64 (2016). https://doi.org/10.1007/s11910-016-0662-5

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