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Spectrométrie de masse en biologie médicale: principes et applications

Mass spectrometry in clinical biology: Principles and applications

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Bio tribune magazine

Résumé

La spectrométrie de masse connaît un engouement certain en biologie médicale, ainsi que l’atteste l’abondante littérature qui lui est consacrée. Elle s’implante ainsi dans les laboratoires de biochimie, de pharmacologie médicale et plus récemment de microbiologie. Cette revue reprend les principes de base de la spectrométrie de masse et les grandes stratégies développées. Les applications actuelles et futures seront abordées.

Abstract

Mass spectrometry has become instrumental in medical biology, as attested by an abundant literature, particularly in biochemistry, medical pharmacology and more recently microbiology laboratories. In this review, we will present the basic principles and strategies using mass spectrometry. Current and future applications will then be discussed.

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Authors and Affiliations

  1. UMR S 945, Université Pierre et Marie Curie-Paris 6, F-75013, Paris, France

    C. Marinach-Patrice & D. Mazier

  2. INSERM, UMR S 945, F-75013, Paris, France

    C. Marinach-Patrice & D. Mazier

  3. Plateforme post-génomique P3S, UPMC, F-75013, Paris, France

    C. Pionneau

  4. AP-HP, groupe hospitalier Pitié-Salpétrière, service parasitologie-mycologie, F-75013, Paris, France

    D. Mazier

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  1. C. Marinach-Patrice
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  2. C. Pionneau
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  3. D. Mazier
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Correspondence to C. Marinach-Patrice.

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Marinach-Patrice, C., Pionneau, C. & Mazier, D. Spectrométrie de masse en biologie médicale: principes et applications. Bio trib. mag. 40, 4–12 (2011). https://doi.org/10.1007/s11834-011-0061-9

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  • DOI: https://doi.org/10.1007/s11834-011-0061-9

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