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Men’s experiences of surviving testicular cancer: an integrated literature review

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Abstract

Purpose

To synthesise literature in order to elucidate the experiences of men who have survived testicular cancer and determine their quality of life following treatment.

Methods

An integrated review sought appropriate literature by utilising a keyword search across seven databases. Retrieved studies were appraised for quality, with 2 qualitative, 12 quantitative and 2 mixed method studies deemed appropriate for this review. The data were extracted and aggregated into categories by way of a thematic analysis. The themes were personal challenges and impact on health, psychological and emotive challenges, perception of reproduction and sexual changes and outlook and support.

Results

Men experienced physical, emotional and sexual difficulties. Some men believed they were infertile, despite evidence that fertility is not compromised in the long term. Psychological conditions can be exacerbated by cultural pressures to conceive and cultural expressions about male identity. Men who had undergone orchidectomy reported minimal impact on their mental health than the men who had chemotherapy or radiotherapy as part of their treatment modality. Sexual dysfunction caused by chemotherapy-associated side effects was detrimental to men’s quality of life. In addition, men who had a partner, who were employed, and who had children were able to adjust better after treatment than those who did not. Provision of clear and honest information post-treatment helped testicular cancer survivors return to their normal lives.

Conclusions

The evidence from the review suggests that the burden of disease for testicular cancer survivors is overall low. Men who had surgical intervention and were treated for testicular cancer experienced minimal impact on their mental health status than the men who had chemotherapy or radiotherapy as part of their treatment modality.

Implications for Cancer Survivors

There is a need to provide appropriate referrals to the relevant services, including psychosocial support, and the development of more adequate communication resources for men following treatment for testicular cancer.

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References

  1. Richardson LC, Neri AJ, Tai E, et al. Testicular cancer: a narrative review of the role of socioeconomic position from risk to survivorship. Urol Oncol. 2012;30(1):95–101.

    Article  PubMed  Google Scholar 

  2. Buljubasic R, Buljubasic M, Bojanac AK, et al. Epigenetics and testicular germ cell tumors. Gene. 2018;661:22–33.

    Article  CAS  PubMed  Google Scholar 

  3. Avci IA, Altinel B. The validity and reliability of health belief scale for testicular Cancer self-examination. Am J Mens Health. 2018;12(3):8.

    Article  Google Scholar 

  4. Australian Institute of Health and Welfare. Burden of cancer in Australia: Australian burden of disease study. 2011. https://www.aihw.gov.au/getmedia/a1aec7bd-ddb7-416f-9a7e-f2133cd5d4cb/20965.pdf.aspx?inline=true. Accessed 20 May 2019.

  5. Le-Cornet C, Lortet-Tieulent J, Forman D, et al. Testicular cancer incidence to rise by 25% by 2025 in Europe? Model-based predictions in 40 countries using population-based registry data. Eur J Cancer. 2014;50(4):831–9.

    Article  PubMed  Google Scholar 

  6. American Cancer Society. Testicular cancer early detection, diagnosis and staging. 2018 https://www.cancer.org/cancer/testicular-cancer/detection-diagnosis-staging.html. Accessed 20 May 2019.

  7. Moore A, Higgins A. Testicular cancer: addressing the psychosexual issues. Br J Nurs. 2009;18(19):1182–6.

    Article  PubMed  Google Scholar 

  8. Skoogh J, Steineck G, Cavallin-Stahl E, et al. Feelings of loss and uneasiness or shame after removal of testicle by orchidectomy: a population-based long-term follow-up of testicular cancer survivors. Int J Androl. 2010;34:183–92.

    Article  Google Scholar 

  9. Hall AE, Boyes AW, Bowman J, Walsh RA, James EL, Girgis A. Young adult cancer survivors' psychosocial well-being: a cross-sectional study assessing quality of life, unmet needs, and health behaviors. Support Care Cancer. 2012;20(6):1333–41.

    Article  PubMed  Google Scholar 

  10. Morman MT. The influence of fear appeals, message, designs and masculinity on men's motivation to perform the testicular self-exam. J Appl Commun Res. 2000;28(2):91–116.

    Article  Google Scholar 

  11. Soon JA, Anton A, Torres J, Lawrence R, Parente P, McKendrick J, et al. Exploring the spectrum of late effects following radical orchidectomy for stage 1 testicular seminoma: a systematic review of the literature. Support Care Cancer. 2019;27:373–82.

    Article  PubMed  Google Scholar 

  12. Eberhard J, Stahl O, Cohn-Cedermark G, et al. Sexual function in men treated for testicular cancer. J Sex Med. 2009;6(7):1979–89.

    Article  PubMed  Google Scholar 

  13. Ryan SJ, Hoyt MA. Adult self-image and well-being after testicular cancer: the role of agency and meaning. Psychol Health. 2018;33(8):1049–61.

    Article  PubMed  PubMed Central  Google Scholar 

  14. Schepisi G, De Padova S, De Lisi D, et al. Psychosocial issues in long-term survivors of testicular Cancer. Frontiers in Endrocrinology. 2019;10(113):1–10.

    Google Scholar 

  15. Whittemore R, Knafl K. The integrative review: updated methodology. J Adv Nurs. 2005;52(5):546–53.

    Article  PubMed  Google Scholar 

  16. Hong QN, Pluye P, Fabregues S, et al. Mixed Methods Appraisal Tool (MMAT) Version 2018 User Guide 2018. http://mixedmethodsappraisaltoolpublic.pbworks.com/w/file/fetch/127916259/MMAT_2018_criteria-manual_2018-08-01_ENG.pdf. Accessed 31 Nov 2018.

  17. Pfaff K, Baxter P, Jack S, Ploeg J. An integrative review of the factors influencing new graduate nurse engagement in inter-professional collaboration. J Adv Nurs. 2014;70:4–20.

    Article  PubMed  Google Scholar 

  18. Saab M, Noureddine S, Huijer HA-S, et al. Surviving testicular Cancer: the Lebanese lived experience. Nurs Res. 2014;63(3):203–10.

    Article  PubMed  Google Scholar 

  19. Caffo O, Amichetti M. Evaluation of sexual life after orchidectomy followed by radiotherapy for early-stage seminoma of the testis. BJU Int. 1999;83:462–8.

    Article  CAS  PubMed  Google Scholar 

  20. Smith AB, Butow P, Olver I, Luckett T, Grimison P, Toner GC, et al. The prevalence, severity, and correlates of psychological distress and impaired health-related quality of life following treatment for testicular cancer: a survivorship study. J Cancer Surviv. 2016;10(2):223–33.

    Article  PubMed  Google Scholar 

  21. Bender JL, Wiljer D, To MJ. Testicular cancer survivors’ supportive care needs and use of online support: a cross-sectional survey. Support Care Cancer. 2012;20:2737–46.

    Article  PubMed  Google Scholar 

  22. Bumbasirevic U, Bojanic N, Pekmezovic T. Health-related quality of life, depression, and sexual function in testicular cancer survivors in a developing country: a Serbian experience. Support Care Cancer. 2013;21:757–63.

    Article  PubMed  Google Scholar 

  23. Fleer J, Sleijfer D, Hoekstra H, Tuinman M, Klip E, Hoekstra-Weebers J. Objective and subjective predictors of cancer-related stress symptoms in testicular cancer survivors. Patient Educ Couns. 2006c;64:142–50.

    Article  PubMed  Google Scholar 

  24. Rudberg L, Carlsson M, Nilsson S, et al. Self-perceived physical, psychologic, and general symptoms in survivors of testicular cancer 3 to 13 years after treatment. Cancer Nurs. 2002;25(3):187–95.

    Article  PubMed  Google Scholar 

  25. Vidrine DJ, Hoekstra-Weebers JEHM, Hoekstra H, Tuinman MA, Marani S, Gritz ER. The effects of testicular Cancer treatment on health-related quality of life. Urology. 2010;75(3):636–41.

    Article  PubMed  Google Scholar 

  26. Shen AH, Howell D, Edwards E, et al. The experience of patients with early-stage testicular cancer during the transition from active treatment to follow-up surveillance. Urol Oncol. 2016;168:e11–20.

    Google Scholar 

  27. Rudberg L, Nilsson S, Wikblad K. Health-related quality of life in survivors of testicular cancer 3 to 13 years after treatment. J Psychol Onc. 2000;18(3):19–31.

    Article  Google Scholar 

  28. Fleer J, Hoekstra HJ, Sleijfer D, et al. Quality of life of testicular cancer survivors and the relationship with sociodemographics, cancer-related variables, and life events. Support Cancer Care. 2006a;14:251–9.

    Article  CAS  Google Scholar 

  29. Kristjanson LJ, Ng C, Oldham L, et al. The impact and responses of men who have experienced testicular cancer. Aust J Cancer Nurs. 2006;7(1):10–7.

    Google Scholar 

  30. Fleer J, Hoekstra HJ, Sleijfer D, Tuinman MA, Hoekstra-Weebers JE. The role of meaning in the prediction of psychosocial well-being of testicular cancer survivors. Qual Life Res. 2006b;15:705–17.

    Article  CAS  PubMed  Google Scholar 

  31. Skoogh J, Steineck G, Johansson B, Wilderäng U, Stierner U, SWENOTECA. Psychological needs when diagnosed with testicular cancer: findings from a population-based study with long-term follow-up. BJU Int. 2013;111:1287–93.

    Article  PubMed  Google Scholar 

  32. Kim C, McGlynn KA, McCorkle R, Li Y, Erickson RL, Ma S, et al. Sexual functioning among testicular cancer survivors: a case-control study in the U.S. J Psychosom Res. 2012;73(1):68–73.

    Article  PubMed  PubMed Central  Google Scholar 

  33. Kim C, McGlynn KA, McCorkle R, et al. Fertility among testicular cancer survivors: a case-study in the U.S. J Cancer Surviv. 2010;4:266–73.

    Article  PubMed  PubMed Central  Google Scholar 

  34. Hashibe M, Abdelaziz S, Al-Temimi M, et al. Long-term health effects among testicular cancer survivors. J Cancer Surviv. 2016;10:1051–7.

    Article  PubMed  PubMed Central  Google Scholar 

  35. Muir A. Counselling patients who have sexual difficulties. Prof Nurse. 2000;15(11):723–6.

    CAS  PubMed  Google Scholar 

  36. Nazareth I, Lewin J, King M. Sexual dysfunction after treatment for testicular cancer: a systematic review. J Psychosom Res. 2001;51(6):735–43.

    Article  CAS  PubMed  Google Scholar 

  37. Dimitropoulous K, Karatzas A, Papandreou C, et al. Sexual dysfunctional testicular cancer patients subjected to post-chemotherapy retroperitoneal lymph node dissection: a focus beyond ejaculation disorders. Andrologia. 2016;48:425–30.

    Article  Google Scholar 

  38. Raphael MJ, Wei X, Karim S, Robinson AG, Bedard PL, Booth CM. Neurotoxicity among survivors of testicular cancer: a population-based study. Clin Oncol. 2019;31:653–8.

    Article  CAS  Google Scholar 

  39. Capogrosso P, Boeri L, Ferrari M. Long-term recovery of normal sexual function in testicular cancer survivors. Asian J Andrology. 2016;18:85–9.

    Article  CAS  Google Scholar 

  40. Alexis O, Worsley AJ. A meta-synthesis of qualitative studies exploring men’s sense of masculinity post-prostate cancer treatment. Cancer Nurs. 2018a;41(4):298–310.

    Article  PubMed  Google Scholar 

  41. Thornton CP. Best practice in teaching male adolescents and young men to perform testicular self examinations: a review. J Pediatr Health Care. 2016;30(6):518–27.

    Article  PubMed  Google Scholar 

  42. Kahn JS. An introduction to masculinities. Wiley-Blackwell: Chichester; 2009.

    Google Scholar 

  43. Darabos K, Hoyt MA. Masculine norms about emotionality and social constraints in younger and older adult men with cancer. J Behav Med. 2017;40:259–70.

    Article  PubMed  Google Scholar 

  44. Dube CE, Fuller BK, Rosen RK, et al. Men’s experiences of physical exams and cancer screening tests: a qualitative study. Prev Med. 2005;40:628–35.

    Article  PubMed  Google Scholar 

  45. Goldzweig G, Andritsch E, Hubert A, Walach N, Perry S, Brenner B, et al. How relevant is marital status and gender variables in coping with colorectal cancer? A sample of middle-aged and older cancer survivors. Psychooncology. 2009;18(8):866–74.

    Article  PubMed  Google Scholar 

  46. Lee TK, Handy AB, Kwan W, Oliffe JL, Brotto LA, Wassersug RJ, et al. Impact of prostate cancer treatment on the sexual quality of life for men-who-have-sex-with-men. J Sex Med. 2015;12:2378–86.

    Article  PubMed  Google Scholar 

  47. McGlynn KA, Trabert B. Adolescent and adult risk factors for testicular cancer. Nat Rev Urol. 2012;9(6):339–49.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  48. Cappuccio F, Rossetti S, Cavaliere C, et al. HRQoL and psychosocial implications in testicular cancer survivors. A literature review. Eur Rev Med Pharmacol Sci. 2018;22(3):645–61.

    CAS  PubMed  Google Scholar 

  49. Fossa SD, Dahl AA, Loge JH. Fatigue, anxiety, and depression in long-term survivors of testicular cancer. J Clin Oncol. 2003;21:1249–54.

    Article  PubMed  Google Scholar 

  50. Gudbergsson SB, Fossa SD, Dahl AA. Is cancer survivorship associated with reduced work engagement? A NOCWO Study. J Cancer Surviv. 2008;2(4):296–302.

    Article  Google Scholar 

  51. Soejima T, Kamibeppu K. Are cancer survivors well-performing workers? A systematic review. Asia Pac J Clin Oncol. 2016;12:e383–97.

    Article  PubMed  Google Scholar 

  52. Johns G. Presenteeism in the workplace: a review and research agenda. J Organ Behav. 2010;31(4):519–42.

    Article  Google Scholar 

  53. Alexis O, Worsley J. The experiences of gay and bisexual men post-prostate cancer treatment: a meta-synthesis of qualitative studies. Am J Mens Health. 2018b;12(6):2076–88.

    Article  PubMed  PubMed Central  Google Scholar 

  54. De Padova S, Casadei C, Berardi A, et al. Caregiver emotional burden in testicular cancer patients: from patient to caregiver support. Front Endocrinol. 2019;10(318):1–7.

    Google Scholar 

  55. Kanera IM, Bolman CAW, Willems RA, Mesters I, Lechner L. Lifestyle related effects of the web-based Kanker Nazorg Wijzer (cancer aftercare guide) intervention for cancer survivors: a randomized controlled trial. J Cancer Surviv. 2016;10:883–97.

    Article  PubMed  PubMed Central  Google Scholar 

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Authors and Affiliations

  1. Faculty of Health and Life Sciences, Oxford Brookes University, Oxford, UK

    Obrey Alexis & Aaron James Worsley

  2. School of Nursing, Midwifery and Social Sciences, CQUniversity, Rockhampton, Australia

    Adeniyi O. Adeleye

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  1. Obrey Alexis
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Correspondence to Aaron James Worsley.

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Alexis, O., Adeleye, A.O. & Worsley, A.J. Men’s experiences of surviving testicular cancer: an integrated literature review. J Cancer Surviv 14, 284–293 (2020). https://doi.org/10.1007/s11764-019-00841-2

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