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Surgical outcomes in 13 patients with bronchopulmonary carcinoid tumors including one recurrent oncocytic carcinoid tumor

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Abstract

Introduction

Bronchopulmonary carcinoids are low-grade tumors for which the standard treatment is surgical resection. We retrospectively evaluated the surgical outcomes.

Methods

Thirteen patients underwent surgical resection for them at our institution between January 2005 and December 2016. We collected their clinicopathologic data to evaluate surgical outcomes.

Results

The 13 patients comprised seven men and six women. Complete resection was performed in all cases. All the tumors were typical carcinoids, including one oncocytic carcinoid which showed highest fluorodeoxyglucose (FDG) uptake (SUVmax 45.7). The 5-year overall survival rates were 100%. The only patient with oncocytic carcinoid developed recurrence of liver metastasis 49 months after the primary lung resection. The metastasis showed low FDG uptake (SUVmax 2.8) and its histology was typical carcinoid and not oncocytic carcinoid.

Conclusion

Surgical outcomes in our patients were favorable. In oncocytic carcinoid, metastatic site may have a radiologic and histologic appearance different from the primary tumor.

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References

  1. Naalsund A, Rostad H, Strom EH, et al. Carcinoid lung tumors—incidence, treatment and outcomes: a population-based study. Eur J Cardiothorac Surg. 2011;39(4):565–9.

    Article  PubMed  Google Scholar 

  2. Tsuta K, Raso MG, Kalhor N, et al. Histologic features of low- and intermediate-grade neuroendocrine carcinoma (typical and atypical carcinoid tumors) of the lung. Lung Cancer. 2011;71(1):34–41.

    Article  PubMed  Google Scholar 

  3. Okereke IC, Taber AM, Griffith RC, et al. Outcomes after surgical resection of pulmonary carcinoid tumors. J Cardiothorac Surg. 2016;11:35.

    Article  PubMed  PubMed Central  Google Scholar 

  4. Tanabe Y, Sugawara Y, Nishimura R, et al. Oncocytic carcinoid tumor of the lung with intense F-18 fluorodeoxyglucose (FDG) uptake in positron emission tomography–computed tomography (PET/CT). Ann Nucl Med. 2013;27(8):781–5.

    Article  CAS  PubMed  Google Scholar 

  5. Bagheri R, Mashhadi M, Haghi SZ, et al. Tracheobronchopulmonary carcinoid tumors: analysis of 40 patients. Ann Thorac Cardiovasc Surg. 2011;17(1):7–12.

    Article  PubMed  Google Scholar 

  6. Filosso PL, Guerrera F, Evangelista A, et al. Prognostic model of survival for typical bronchial carcinoid tumours: analysis of 1109 patients on behalf of the European Association of Thoracic Surgeons (ESTS) Neuroendocrine Tumours Working Group. Eur J Cardiothorac Surg. 2015;48(3):441–7.

    Article  PubMed  Google Scholar 

  7. Chang A, Harawi SJ. Oncocytes, oncocytosis, and oncocytic tumors. Pathol Annu. 1992;27(1):263–304.

    PubMed  Google Scholar 

  8. Song YS, Lee WW, Chung JH, et al. Correlation between FDG uptake and glucose transporter type 1 expression in neuroendocrine tumors of the lung. Lung Cancer. 2008;61(1):54–60.

    Article  PubMed  Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Thoracic Surgery, National Hospital Organization, Shikoku Cancer Center, 160 Minami-Umemoto, Matsuyama, 791-0280, Japan

    Tsuyoshi Ueno, Yuho Maki, Ryujiro Sugimoto, Motohiro Yamashita & Kentaro Nakata

  2. Department of Diagnostic Radiology, National Hospital Organization, Shikoku Cancer Center, Matsuyama, Japan

    Yoshifumi Sugawara

  3. Department of Pathology, National Hospital Organization, Shikoku Cancer Center, Matsuyama, Japan

    Rieko Nishimura & Norihiro Teramoto

Authors
  1. Tsuyoshi Ueno
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  2. Yuho Maki
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  3. Ryujiro Sugimoto
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  4. Motohiro Yamashita
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  5. Kentaro Nakata
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  6. Yoshifumi Sugawara
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  7. Rieko Nishimura
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  8. Norihiro Teramoto
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Corresponding author

Correspondence to Tsuyoshi Ueno.

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The authors have declared that no conflict of interest exists.

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Ueno, T., Maki, Y., Sugimoto, R. et al. Surgical outcomes in 13 patients with bronchopulmonary carcinoid tumors including one recurrent oncocytic carcinoid tumor. Gen Thorac Cardiovasc Surg 67, 486–489 (2019). https://doi.org/10.1007/s11748-018-0967-1

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  • DOI: https://doi.org/10.1007/s11748-018-0967-1

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