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Submucosal Tunneling Endoscopic Resection for Gastric Submucosal Tumors: a Comparison Between Cardia and Non-cardia Location

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Journal of Gastrointestinal Surgery Aims and scope

Abstract

Background and Purpose

Submucosal tunneling endoscopic resection (STER) was initially used to remove submucosal tumors (SMTs) located at the esophagus and cardia; only few researchers have reported the feasibility of STER for gastric SMTs beyond cardia due to the technical difficulty, and little is known about the comparison of STER for cardia and non-cardia gastric SMTs. The purpose was to compare the feasibility and efficacy of STER for cardia and non-cardia gastric SMTs, as well as to explore the risk factors for failure of en bloc resection.

Methods

We retrospectively collected the clinical data about patients with gastric SMTs who received STER at our hospital from June 2012 to June 2018. Demographics, tumor size, procedure-related parameters, complications, hospital stay, and follow-up data were compared between cardia and non-cardia SMTs. And multivariate analyses were conducted to look for the risk factors for failure of en bloc resection.

Results

A total of 46 SMTs were removed, and 25 of them were located at cardia, while the other 21 at non-cardia position. There was no significant difference between the two groups in terms of gender, age, tumor size, en bloc resection rate, operation time, complications, and hospital stay (p > 0.05). No recurrence was noticed in all the cases. Multivariate analyses revealed that irregular shape was an independent risk factor for failure of en bloc resection.

Conclusion

STER is feasible for both cardia and non-cardia gastric SMTs, and the efficacy between cardia and non-cardia location is comparable. Irregular shape was an independent risk factor for failure of en bloc resection.

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Grant Support

This study was funded by Development and Reform Commission of Hunan Province (XFGTZ2014713).

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Authors and Affiliations

  1. Department of Gastroenterology, The Second Xiangya Hospital, Central South University, No. 139 Middle Renmin Road, Changsha, 410011, Hunan, China

    Yuyong Tan, Bingyi Zhou, Shilan Zhang, Feihong Deng, Rong Li, Shan Gao, Jirong Huo & Deliang Liu

Authors
  1. Yuyong Tan
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  2. Bingyi Zhou
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  3. Shilan Zhang
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  4. Feihong Deng
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  5. Rong Li
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  6. Shan Gao
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  7. Jirong Huo
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  8. Deliang Liu
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Contributions

Conception of the work: YT and DL; acquisition, analysis, and interpretation of the data: YT, BZ, SZ, FD, RL, and SG; drafting the manuscript: YT; critically revise for important intellectual content: JH and DL; final approve of the manuscript: all authors.

Corresponding author

Correspondence to Deliang Liu.

Ethics declarations

This is a single-center, retrospective study and was approved by the ethics committee of the Second Xiangya Hospital of Central South University, and all the patients signed informed consent.

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Cite this article

Tan, Y., Zhou, B., Zhang, S. et al. Submucosal Tunneling Endoscopic Resection for Gastric Submucosal Tumors: a Comparison Between Cardia and Non-cardia Location. J Gastrointest Surg 23, 2129–2135 (2019). https://doi.org/10.1007/s11605-019-04182-4

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  • DOI: https://doi.org/10.1007/s11605-019-04182-4

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