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Effects of a resistance training programme in people living with HIV in Zimbabwe

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A Correction to this article was published on 17 August 2020

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Abstract

Purpose

Combination antiretroviral therapy (cART) increases life expectancy in people living with HIV (PLWH). However, receiving cART coupled with physical inactivity increases the risk of developing non-communicable diseases. The purpose of this study was to investigate the effect of resistance training (RT) on body composition, laboratory analysis and strength values in PLWH receiving cART in Zimbabwe.

Methods

One-hundred and twenty-eight PLWH receiving cART, aged 18–45 years were purposely recruited to saturation. Two districts in Zimbabwe were used, participants in Budiriro were randomly assigned for convenience to an experimental (EXP) group (n = 64) performing RT 3 days/week and participants in Mabvuku to a control (CON) group (n = 64) for 12 weeks of no exercise. Body mass index, waist-to-hip ratio, percentage body fat, lean body mass (body composition), laboratory analysis profiles and one-repetition maximum (1RM) strength were measured at baseline (BL) and after 12 weeks (W12) in both groups.

Results

In the EXP group W12, lean body mass increased (p < .001), fasting blood glucose decreased (p < .001), fasting total blood cholesterol decreased (p < .001), 66% of participants improved resting blood pressure and 1RM muscular strength increased (p < .001).

Conclusions

These findings highlight the benefits of RT for PLWH receiving cART. This demonstrates the need for additional public health initiatives involving RT in this population in sub-Saharan Africa.

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Change history

  • 17 August 2020

    Unfortunately, the first author name was not included in the author group of original publication.

Abbreviations

cART:

Combination antiretroviral therapy

PLWH:

People living with HIV

RT:

Resistance training

EXP:

Experimental

CON:

Control

1RM:

One-repetition maximum

BL:

Baseline

W12:

After week 12

BREC:

Biomedical research ethics committee

MRCZ:

Medical research council of zimbabwe

IPAR-Q:

International physical activity readiness questionnaire

BMI:

Body mass index

WHR:

Waist-to-hip ratio

ISAK:

International society for the advancement of kinanthropometry

HIV:

Human immunodeficiency virus

kg:

Kilogram

mmHg:

Millimetres of mercury

mmol/L:

Millimoles per litre

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Acknowledgements

The authors would like to acknowledge the College of Health Sciences at the University of KwaZulu-Natal, Westville, for funding received.

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Authors and Affiliations

  1. Durban, South Africa

    Victor Mbayo & Takshita Sookan

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  1. Victor Mbayo
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  2. Takshita Sookan
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Contributions

VM was the primary author and principal investigator of the study. TS, was key to concept development, manuscript writing, editing and revising. All authors approved the final submission.

Corresponding author

Correspondence to Takshita Sookan.

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Conflict of interest

The authors declare that they have no conflict of interest.

Human and animal rights

All procedures performed in this study were in accordance with the University of Kwa-Zulu Natal’s Biomedical Research Ethics Committee (BREC) BF293/15, Medical Research Council of Zimbabwe (MRCZ) MRCZ/B/948 and with the 1964 Helsinki declaration as well as its amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Mbayo, V., Sookan, T. Effects of a resistance training programme in people living with HIV in Zimbabwe. Sport Sci Health 16, 551–560 (2020). https://doi.org/10.1007/s11332-020-00658-y

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