Skip to main content

Advertisement

Log in

Invasive squamous cell carcinoma arising in an inverted papilloma involving oral cavity

  • Case Report
  • Published:
Oral Radiology Aims and scope Submit manuscript

Abstract

Inverted papilloma (IP) is a benign tumour characterized by the growth of epithelial cells downward into the underlying supportive tissue. The tumour derives from the lining mucosa of the nasal cavity and paranasal sinuses. IP typically arises as a unilateral lesion from the lateral wall of the nasal cavity and extends secondarily to the paranasal sinuses. The aggressive behaviour of IP causing local invasion, its tendency for local recurrence, and its propensity to be associated with carcinoma constitute serious complications. This paper describes a very rare case of IP associated with squamous cell carcinoma, extending into paranasal sinuses, causing destruction of the bony wall of maxillary sinus and involvement of the oral cavity.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5

Similar content being viewed by others

References

  1. Slootweg PJ, Chan JKC, Stelow EB, Thompson LDR. Tumors of the nasal cavity, paranasal sinuses and skull base. In: El-Naggar AK, Chan JKC, Grandis JF, Takata T, Slootweg PJ, editors. WHO classification of head and neck tumors. 4th ed. Lyon: IARC; 2017. p. 14–27.

    Google Scholar 

  2. Lund VJ, Stammberger H, Nicolai P, Castelnuovo P, Beal T, Beham A, et al. European position paper on endoscopic management of tumours of the nose, paranasal sinuses and skull base. Rhinology. 2010;Suppl 22:1–143.

    Google Scholar 

  3. Mirza S, Bradley PJ, Acharya A, Stacey M, Jones NS. Sinonasal inverted papillomas: recurrence, and synchronous and metachronous malignancy. J Laryngol Otol. 2007;121:857–64.

    Article  Google Scholar 

  4. Lawson W, Ho BT, Shaari CM, Biller HF. Inverted papilloma: a report of 112 cases. Laryngoscope. 1995;105:282–8.

    Article  Google Scholar 

  5. Ojiri H, Ujita M, Tada S, Fukuda K. Potentially distinctive features of sinonasal inverted papilloma on MR imaging. Am J Roentgenol. 2000;175:465–8.

    Article  Google Scholar 

  6. Hempenstall PD, Savage NW. Inverted papilloma of the maxillary sinus: an unusual cause of a non-healing extraction socket. Case report. Aust Dent J. 1990;35:241–4.

    Article  Google Scholar 

  7. Piva MR, Santos Tde S, Martins Filho PR, Kumar PN, Souza LM, Silva LC. Inverted papilloma (Schneiderian papilloma) with involvement of the oral cavity: report of an unusual case. An Bras Dermatol. 2011;86:779–83.

    Article  Google Scholar 

  8. Garcia AS, Bravo-Calderon DM, Ferreira MP, Oliveira DT. Squamous cell carcinoma arising from inverted schneiderian papilloma: a case report with oral involvement. Case Rep Otolaryngol. 2014;2014:478092.

    PubMed  PubMed Central  Google Scholar 

  9. Lisan Q, Laccourreye O, Bonfils P. Sinonasal inverted papilloma: From diagnosis to treatment. Eur Ann Otorhinolaryngol Head Neck Dis. 2016;133:337–41.

    Article  Google Scholar 

  10. Chawla A, Shenoy J, Chokkappan K, Chung R. Imaging features of sinonasal inverted papilloma: a pictorial review. Curr Probl Diagn Radiol. 2016;45:347–53.

    Article  Google Scholar 

  11. Maroldi R, Farina D, Palvarini L, Lombardi D, Tomenzoli D, Nicolai P. Magnetic resonance imaging findings of inverted papilloma: differential diagnosis with malignant sinonasal tumors. Am J Rhinol. 2004;18:305–10.

    Article  Google Scholar 

  12. Jeon TY, Kim HJ, Chung SK, Dhong HJ, Kim HY, Yim YJ, et al. Sinonasal inverted papilloma: value of convoluted cerebriform pattern on MR imaging. AJNR Am J Neuroradiol. 2008;29:1556–60.

    Article  Google Scholar 

  13. Savy L, Lloyd G, Lund VJ, Howard D. Optimum imaging for inverted papilloma. J Laryngol Otol. 2000;114:891–3.

    Article  Google Scholar 

  14. Head CS, Sercarz JA, Luu Q, Collins J, Blackwell KE. Radiographic assessment of inverted papilloma. Acta Otolaryngol. 2007;127:515–20.

    Article  Google Scholar 

  15. Zinreich SJ, Kennedy DW, Malat J, Curtin HD, Epstein JI, Huff LC, et al. Fungal sinusitis: diagnosis with CT and MR imaging. Radiology. 1988;169:439–44.

    Article  Google Scholar 

  16. Allbery SM, Chaljub G, Cho NL, Rassekh CH, John SD, Guinto FC. MR imaging of nasal masses. Radiographics. 1995;15:1311–27.

    Article  Google Scholar 

  17. Sham CL, King AD, van Hasselt A, Tong MC. The roles and limitations of computed tomography in the preoperative assessment of sinonasal inverted papillomas. Am J Rhinol. 2008;22:144–50.

    Article  Google Scholar 

  18. Miyazaki T, Haku Y, Yoshizawa A, Iwanaga K, Fujiwara T, Mizuta M, et al. Clinical features of nasal and sinonasal inverted papilloma associated with malignancy. Auris Nasus Larynx. 2018;45:1014–9.

    Article  Google Scholar 

  19. Yu MS, Lim WS, Lee BJ, Chung YS. Squamous cell carcinoma associated with inverted papilloma of the maxillary sinus: our experience with 21 patients. Clin Otolaryngol. 2017;42:1048–52.

    Article  Google Scholar 

Download references

Acknowledgements

This work was presented as a poster presentation at the 2019 International Congress of Oral Diagnosis and Maxillofacial Radiology Society, April 25–28, Antalya, Turkey.

Funding

None.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Nagihan Koç.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Human rights statement and informed consent

All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1975, as revised in 2008 (5). Informed consent was obtained from the patient included in this study.

Animal rights statement

This article does not contain any studies with animal subjects performed by any of the authors.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Koç, N., Boyacıoğlu, H., Avcu, N. et al. Invasive squamous cell carcinoma arising in an inverted papilloma involving oral cavity. Oral Radiol 36, 209–214 (2020). https://doi.org/10.1007/s11282-020-00423-4

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11282-020-00423-4

Keywords

Navigation