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Evaluation of the Bioavailability and Health Risks of Cadmium in Potato Using Three In Vitro Methods

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Abstract

In this study, PBET (Physiologically Based Extraction Test), IVG (In Vitro Gastrointestinal), and SBRC (Solubility Bioavailability Research Consortium) were used to compare the bioavailability of Cd in 10 potato varieties and evaluate the risks to human health. The results show that the dissolved Cd content in the gastric and small intestine phase under the three methods is IVG > SBRC > PBET. The most bioavailable method in the gastric and small intestine phases is IVG, and the varieties are Weiyu 5 and Weiyu 7. In the gastric phase, Weiyu 7 had the highest availability, at 73.36%, and in the small intestine phase, Weiyu 5 had the highest availability at 67.48%, and compared with SBRC and PBET, the difference reached a significant level; the varieties with higher bioavailability are Weiyu 5 and Weiyu 7, and the lower varieties are Lishu 13 and Lishu 15 among the 10 potato varieties. Three methods were used to assess the human health risk of Cd in potatoes. The HQ values ​of different varieties were all less than 1. The ADD and HQ values of Cd ingested by adults and children through potato are generally IVG > SBRC > PBET.

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Data Availability

All data generated or analyzed during this study are included in this published article (and its supplementary information files).

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Acknowledgements

We thank the College of Agriculture of Guizhou University for providing a platform for our experiment, and the Potato Research Institute of Guizhou Academy of Agricultural Sciences for providing test materials.

Funding

This work was supported by the Qianke He Foundation under Grant number [2019]1103; the National Natural Science Foundation of China under Grant number 21866008; and Qianke He Houbuzhu under Grant number [2020]3001.

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Authors and Affiliations

  1. College of Agriculture, West Campus of Guizhou University, Huaxi District, Guiyang City, Guizhou Province, China

    Xue He, Ke Liu, Wei Li, Jie Zhang, Chun Mao & Jihong Feng

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  1. Xue He
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  2. Ke Liu
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  3. Wei Li
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  4. Jie Zhang
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  5. Chun Mao
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  6. Jihong Feng
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Contributions

All authors contributed to the study conception and design. Material preparation, data collection and analysis were performed by Wei Li, Chun Mao, and Jihong Feng. The first draft of the manuscript was written by Xue He and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.

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Correspondence to Ke Liu.

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He, X., Liu, K., Li, W. et al. Evaluation of the Bioavailability and Health Risks of Cadmium in Potato Using Three In Vitro Methods. Water Air Soil Pollut 233, 131 (2022). https://doi.org/10.1007/s11270-022-05548-2

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