We developed an optoacoustic tomograph with hand-held probe designed for optoacoustic imaging of biological tissues. The hand-held probe consists of a fiber-optic bundle for delivery of pulsed laser radiation to the studied object and a cylindrical focusing 64-element antenna for the detection of optoacoustic pulses. The capabilities of the tomograph to visualize the model blood vessels were studied experimentally using electronic and electronic–mechanical scanning. The achieved axial/lateral spatial resolution is 200/400 μm, the imaging depth is 18 mm, and the maximum B-scan acquisition rate is 10 Hz.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
T.Khokhlova, I.Pelivanov, and A.Karabutov, Acoust. Phys., 55, Nos. 4–5, 674 (2009).
A.Orlova, I.Turchin, V.Plehanov, et al., Laser Phys. Lett., 5, No. 4, 321 (2008).
L. V.Wang and S.Hu, Science, 335, No. 6075, 1458 (2012).
L. A. Matveev, V.V. Zaitsev, G.V.Gelikonov, et al., Opt. Lett., 40, No. 7, 1472 (2015).
R. A.Kruger, R.B. Lam, D.R.Reinecke, et al., Medical Phys., 37, No. 11, 6096 (2010).
D. Jasaitiene, S.Valiukeviciene, G. Linkeviciute, et al., J. European Academy Dermatology Venerology, 25, No. 4, 375 (2011).
P. Subochev, I.Fiks, and M.Frenz, Laser Phys. Lett., 13, No. 2, 025605 (2016).
P.V. Subochev, A.G. Orlova, I.V.Turchin, and A.M. Sergeev, Dokl. Phys., 59, No. 2, 59 (2014).
P. Subochev, Opt. Lett., 41, No. 5, 1006 (2016).
A.Taruttis and X. Ntziachristos, Nature Photonics, 9, No. 4, 219 (2015).
S. Preisser, N. L.Bush, A.G.Gertsch-Grover, et al., J. Biomedical Opt., 18, No. 2, 026011 (2013).
I.Petrov, Y. Petrov, D. Prough, et al., Opt. Express, 20, No. 4, 4159 (2912).
A.P. Jathoul, J. Laufer, O.Ogunlade, et al., Nature Photonics, 9, 239 (2015).
J. Ripoll, B.Koberstein-Schwarz, and V. Ntziachristos, Trends Biotechn., 33, No. 11, 679 (2015).
M.Omar, D. Soliman, J.Gateau, and V.Ntziachristos, Opt. Lett., 39, No. 13, 3911 (2014).
A.Rosenthal, V. Ntziachristos, and D.Razansky, Current Medical Imaging Rev., 9, No. 4, 318 (2013).
P. Subochev, A.Katichev, A.Morozov, et al., Opt. Lett., 37, No. 22, 4606 (2012).
P. Subochev, A. Orlova, M. Shirmanova., et al., Biomed. Opt. Express, 6, No. 2, 631 (2015).
L. V.Wang, Nature Photonics, 3, No. 9, 503 (2009).
D. Razansky, A.Buehler, and V.Ntziachristos, Nature Protocols, 6, No. 8, 1121 (2011).
V.Kozhushko, T.Khokhlova, A. Zharinov, et al., J. Acoust. Soc. Am., 116, No. 3, 1498 (2004).
T. D.Khokhlova, I. V. Pelivanov, V.V.Kozhushko, et al., Appl. Opt., 46, No. 2, 262 (2007).
“ANSI Z136.1. American national standard for safe use of lasers,” Laser Institute of America, Orlando, USA (2007).
T.Khokhlova, I.Pelivanov, and A.Karabutov, Appl. Phys. Lett., 92, No. 2, 024105 (2008).
M. Jaeger, S. Schüpbach, A.Gertsch, et al., Inverse Problems, 23, No. 6, S51 (2007).
V. Ntziachristos and D. Razansky, Chem. Rev., 110, No. 5, 2783 (2010).
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Izvestiya Vysshikh Uchebnykh Zavedenii, Radiofizika, Vol. 60, No. 3, pp. 260–267, March 2017.
Rights and permissions
About this article
Cite this article
Subochev, P., Postnikova, A.S., Koval’chuk, A. et al. Biomedical Optoacoustic Tomograph Based on a Cylindrical Focusing PVDF Antenna. Radiophys Quantum El 60, 233–239 (2017). https://doi.org/10.1007/s11141-017-9794-y
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11141-017-9794-y