Abstract
Trehalose has been widely used as a kind of food additives. But in recent years, with several new studies of trehalose, some harmful effects had also been found. Drosophila melanogaster was used as a model organism to explore whether trehalose affects the lifespan. The results showed that high concentrations of trehalose could significantly shorten the lifespan of female flies by 12.5%, when compared to controls.
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Funding
This work was supported by the grant to J.S. (Zhejiang Provincial Natural Science Foundation of China, LY22C060002).
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Yifan Xu and Jie Shen wrote the main manuscript. And Xingyou Liu prepared Fig. 1 and Sup Table 1. Hao Tang and LiChao Zhong prepared Sup Tables 2–3. Xiang Zhu do the experiment. All reviewed the manuscript.
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Xu, Y., Liu, X., Tang, H. et al. Chronic Consumption of Trehalose Reduces Lifespan in Drosophila Model. Plant Foods Hum Nutr 78, 228–229 (2023). https://doi.org/10.1007/s11130-023-01044-y
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DOI: https://doi.org/10.1007/s11130-023-01044-y