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A review from patents inspired by two plant genera: Uncaria and Hamelia

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Abstract

Specialized or secondary metabolism of plants from two genera, Uncaria and Hamelia, has been widely studied generating a huge investment in research and development of patents. This review highlights the most recent patents granted so far, with some exceptions, covering different areas of knowledge including biotechnological aspects of plant specialized/secondary metabolism. Several patent databases were consulted in order to collect patent information. There are patents for specialized/secondary metabolite isolation methods, synthesis, production, genes, development of medicaments, drug delivery systems, equipment, machines, industrial processes, plant culture techniques, and new plant varieties, among others. This review of the state-of-the art about patents related to Uncaria and Hamelia, as well as their metabolites, can be a valuable source of organized information for those researchers developing projects in many aspects related to these two genera. Uncaria and Hamelia have an enormous potential to become important economically crops.

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Abbreviations

CYP450:

Cytochrome P450

IgE:

Immunoglobulin E

MIA:

Monoterpenoid indole alkaloid

MOA:

Monoterpenoid oxindole alkaloid

HIV/AIDS:

Human immunodeficiency virus infection and acquired immune deficiency syndrome

HPLC:

High-performance liquid chromatography

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Acknowledgements

I.J.F.S. received a postdoctoral fellowship from CONACYT (Mexico). We thank to Prof.em.dr. Robert Verpoorte (IBL, Leiden University, The Netherlands) and Dr. Carlos M. Cerda-García-Rojas (Department of Chemistry, Cinvestav-IPN, Mexico) for their helpful suggestions and discussions.

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  1. Departamento de Biotecnología y Bioingeniería, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Av. IPN 2508, Col. San Pedro Zacatenco, 07360, Mexico City, Mexico

    Isvett Josefina Flores-Sanchez & Ana Carmela Ramos-Valdivia

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  1. Isvett Josefina Flores-Sanchez
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  2. Ana Carmela Ramos-Valdivia
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Correspondence to Ana Carmela Ramos-Valdivia.

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Flores-Sanchez, I.J., Ramos-Valdivia, A.C. A review from patents inspired by two plant genera: Uncaria and Hamelia . Phytochem Rev 16, 693–723 (2017). https://doi.org/10.1007/s11101-017-9498-0

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