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A Crosstalk on Antimicrobial Peptides

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Abstract

Antimicrobial peptides (AMPs) are small sized protein molecules which play a crucial role in host inborn immune framework. AMPs with their specific properties are often considered as a barrier against various harmful foreign particles including bacteria, yeast, fungi and virus. These peptides from different sources exhibit diverse functions and structural features. It exploits the unique property of membrane interaction to destroy target organisms and even cellular components are targeted. However, to combat the emerging resistance towards antibiotics, the use of AMPs as natural drugs has gained importance. Efficiency of these peptides can be enhanced by modification in different aspects through in silico approach. In this article we focus on the areas on antimicrobial peptides like source, properties, classification, mechanism of action, resistance and strategies for its applications.

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  1. Department of Biotechnology, Assam University, Silchar, Assam, 788011, India

    Ankita Borah, Bornali Deb & Supriyo Chakraborty

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Borah, A., Deb, B. & Chakraborty, S. A Crosstalk on Antimicrobial Peptides. Int J Pept Res Ther 27, 229–244 (2021). https://doi.org/10.1007/s10989-020-10075-x

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