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Incidence and Risk of Depression Associated with Diabetes in Adults: Evidence from Longitudinal Studies

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Abstract

This meta-analysis examined depression as a consequence of diabetes by conducting a meta-analysis, using data from longitudinal studies. Databases were systematically searched for relevant studies. Incidence of depression is presented as cumulative incident proportion (CIP). Pooled effect sizes were calculated using random-effects model. The data were reconstructed to compute relative risk (RR) and CIP. The 16 studies selected for review generated 16 datasets of which 11 studies reporting binary estimates (RR) and 5 studies reporting time-to-event estimates [hazard ratio (HR)]. Both RR and HR were significant at 1.27 (95 % CI 1.17–1.38) and 1.23 (95 % CI 1.08–1.40) for incident depression associated with diabetes mellitus. Our observations also revealed greater cumulative incidence of depression in diabetes than in non diabetes groups. Our study shows that diabetes is a significant risk factor for the onset of depression.

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Conflict of interest

The authors declare that they have no conflict of interest. The author(s) received no financial support for the research, authorship, and/or publication of this article.

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Authors and Affiliations

  1. School of Pharmacy, The University of Queensland, 20 Cornwall Street, Woolloongabba, QLD, 4102, Australia

    Syed Shahzad Hasan, Alexandra M. Clavarino & Therese Kairuz

  2. School of Population Health, The University of Queensland, Herston Road, Herston, QLD, 4006, Australia

    Abdullah A. Mamun

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  1. Syed Shahzad Hasan
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  2. Abdullah A. Mamun
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  3. Alexandra M. Clavarino
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  4. Therese Kairuz
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Correspondence to Syed Shahzad Hasan.

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Hasan, S.S., Mamun, A.A., Clavarino, A.M. et al. Incidence and Risk of Depression Associated with Diabetes in Adults: Evidence from Longitudinal Studies. Community Ment Health J 51, 204–210 (2015). https://doi.org/10.1007/s10597-014-9744-5

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  • DOI: https://doi.org/10.1007/s10597-014-9744-5

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