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Marine actinobacteria: perspectives, challenges, future directions

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Abstract

In this paper we evaluate the current state of research on the biology and biotechnology of marine actinobacteria. The topics covered include the abundance, diversity, novelty and biogeographic distribution of marine actinobacteria, ecosystem function, bioprospecting, and a new approach to the exploration of actinobacterial taxonomic space. An agenda for future marine actinobacterial research is suggested based upon consideration of the above issues.

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References

  • J. Adamczyk M. Hesselsoe N. Iversen M. Horn A. Lehner P.H. Nielsen M. Schloter P. Roslev M. Wagner (2003) ArticleTitleThe isotope array, a new tool that employs substrate-mediated labeling of rRNA for determination of microbial community structure and function Appl. Environ. Microbiol. 69 6875–6887 Occurrence Handle14602652 Occurrence Handle1:CAS:528:DC%2BD3sXptVykurw%3D

    PubMed  CAS  Google Scholar 

  • A.L. Alldredge M.W. Silver (1988) ArticleTitleCharacteristics, dynamics and significance of marine snow Prog. Oceanog. 20 41–82

    Google Scholar 

  • F. Barbosa D. Horvath (2004) ArticleTitleMolecular similarity and property similarity Curr. Top. Med. Chem. 4 589–600 Occurrence Handle14965296 Occurrence Handle1:CAS:528:DC%2BD2cXjtVeis74%3D

    PubMed  CAS  Google Scholar 

  • O. Beja (2004) ArticleTitleTo BAC or not to BAC: marine ecogenomics Curr. Op. Biotechnol. 15 187–190 Occurrence Handle1:CAS:528:DC%2BD2cXkvV2gurw%3D

    CAS  Google Scholar 

  • J.W. Blunt B.R. Copp M.H.G. Munro P.T. Northcote M.R. Prisep (2004) ArticleTitleMarine natural products Nat. Prod. Rep. 21 1–49 Occurrence Handle15039834 Occurrence Handle1:CAS:528:DC%2BD2cXisFWgtLs%3D

    PubMed  CAS  Google Scholar 

  • H.T.S. Boschker S.C. Nold Wellsbury P. D. Bos W. de Graaf R. Pel R.J. Parkes T.E. Cappenberg (1998) ArticleTitleDirect linking of microbial populations to specific biogeochemical processes by 13C-labelling of biomarkers Nature 392 801–805 Occurrence Handle1:CAS:528:DyaK1cXivF2gtbg%3D

    CAS  Google Scholar 

  • P.F.B. Brandão A.T. Bull (2003) ArticleTitleNitrile hydrolysing activities of deep-sea and terrestrial mycolate actinomycetes Antonie van Leeuwenhoek 84 89–98 Occurrence Handle14533712

    PubMed  Google Scholar 

  • P.F.B. Brandão M. Torimura R. Kurane A.T. Bull (2002a) ArticleTitleDereplication for biotechnology screening: PyMS analysis and PCR-RFLP-SSCP (PRS) profiling of 16S rRNA genes of marine and terrestrial actinomycetes Appl . Microbiol. Biotechnol. 58 77–83

    Google Scholar 

  • P.F.B. Brandão J.P. Clapp A.T. Bull (2002b) ArticleTitleDiscrimination and taxonomy of geographically diverse strains of nitrile-metabolising actinomycetes using chemometric and molecular sequencing techniques Environ. Microbiol. 4 262–276

    Google Scholar 

  • P.F.B. Brandão J.P. Clapp A.T. Bull (2003) ArticleTitleDiversity of nitrile hydratase and amidase genes in Rhodococcus erythropolis strains recovered from geographically distinct habitats Appl. Environ. Microbiol. 69 5754–5766 Occurrence Handle14532022

    PubMed  Google Scholar 

  • J.H. Brown M.V. Lomolino (1998) Biogeography. 2nd. ed Sinauer Associates, Inc. SunderlandMass

    Google Scholar 

  • A. Bruns H. Philipp H. Cypionka T. Brinkhoff (2003) ArticleTitleAeromicrobium marinum sp nov., an abundant pelagic bacterium isolated from the German Wadden Sea Antonie van Leeuwenhoek 53 1917–1923 Occurrence Handle1:CAS:528:DC%2BD2cXhtF2huw%3D%3D

    CAS  Google Scholar 

  • A.T. Bull (2004a) Microbial Diversity and Bioprospecting ASM Press Washington, DC xv + 1–496

    Google Scholar 

  • A.T. Bull (2004b) The paradigm shift in microbial prospecting A.T. Bull (Eds) Microbial Diversity and Bioprospecting ASM Press Washington, DC 241–249

    Google Scholar 

  • A.T. Bull (2004c) Microbial ecology – the key to discovery. How to look, where to look A.T. Bull (Eds) Microbial Diversity and Bioprospecting ASM Press Washington, DC 71–79

    Google Scholar 

  • A.T. Bull M. Goodfellow J.H. Slater (1992) ArticleTitleBiodiversity as a source of innovation in biotechnology Annu. Rev. Microbiol. 42 219–257

    Google Scholar 

  • A.T. Bull A.C. Ward M. Goodfellow (2000) ArticleTitleSearch and discovery strategies for biotechnology: the paradigm shift Microbiol. Molec. Biol. Rev. 64 573–606 Occurrence Handle1:CAS:528:DC%2BD3cXntVCgtL8%3D

    CAS  Google Scholar 

  • J.-C. Cho J.M. Tiedje (2000) ArticleTitleBiogeography and degree of endemism of fluorescent Pseudomonas strains in soil Appl. Environ. Microbiol. 66 5448–5456 Occurrence Handle11097926 Occurrence Handle1:CAS:528:DC%2BD3MXjsVygs7o%3D

    PubMed  CAS  Google Scholar 

  • J.A. Colquhoun J. Zulu M. Goodfellow K. Horikoshi A.C. Ward A.T. Bull (2000) ArticleTitleRapid characterisation of deep-sea actinomycetes for biotechnology screening programmes Antonie van Leeuwenhoek 77 359–367 Occurrence Handle10.1023/A:1002627314735 Occurrence Handle1:STN:280:DC%2BD3M%2FmvVCksQ%3D%3D Occurrence Handle10959565

    Article  CAS  PubMed  Google Scholar 

  • F. Colwell R. Matsumoto D. Reed (2004) ArticleTitleA review of gas hydrates, geology, and biology of the Nankai Trough Chem. Geol. 205 391–404 Occurrence Handle1:CAS:528:DC%2BD2cXjsFOktrs%3D

    CAS  Google Scholar 

  • K.L. Cook G.S. Sayler (2003) ArticleTitleEnvironmental application of array technology: promiseproblems and practicalities Curr. Op. Biotechnol. 14 311–318 Occurrence Handle1:CAS:528:DC%2BD3sXltVSqs7o%3D

    CAS  Google Scholar 

  • E.F. DeLong (2001) ArticleTitleMicrobial seascapes revisited Curr. Op. Microbiol. 4 290–295 Occurrence Handle1:CAS:528:DC%2BD3MXltVKktbY%3D

    CAS  Google Scholar 

  • E.F. DeLong E.G. Franks A.L. Alldredge (1993) ArticleTitlePhylogenetic diversity of aggregate-attached vs. free-living marine bacterial assemblages Limnol. Oceanogr. 38 924–934 Occurrence Handle10.4319/lo.1993.38.5.0924

    Article  Google Scholar 

  • J.W. Deming P.L. Yager (1992) Natural bacterial assemblages in deep-sea sediments: towards a global view G.T. Rowe V. Pariente (Eds) Deep-sea food chains and the global carbon cycle Kluwer Academic Publishers Dordrecht 11–27

    Google Scholar 

  • J.L. Dixon C. Turley (2001) ArticleTitleMeasuring bacterial production in deep-sea sediments using H-3-thymidine incorporation: ecological significance Microbial Ecol. 42 549–561 Occurrence Handle1:CAS:528:DC%2BD38XntFWqtw%3D%3D

    CAS  Google Scholar 

  • A. Dress D. Huson V. Moulton (1996) ArticleTitleAnalyzing and visualizing sequence and distance data using SPLITSTREE Discrete Appl. Math. 71 95–109

    Google Scholar 

  • Fiedler H.-P., Bruntner C., Bull A.T., Ward A.C., Goodfellow M., Potterat O., Puder C. and Mihm G. 2004. Marine actinomycetes as a source of novel secondary metabolites. Antonie van Leeuwenhoek 87: 37–42 (this issue).

    Google Scholar 

  • B.J Finlay G.F. Esteban (2004) Ubiquitous dispersal of free-living microorganisms A.T. Bull (Eds) Microbial Diversity and Bioprospecting. ASM Press Washington, DC 241–249

    Google Scholar 

  • B.J. Finlay T. Fenchel (2004) ArticleTitleCosmopolitan metapopulations of free-living microbial eukaryotes Protist 155 237–244 Occurrence Handle15305798

    PubMed  Google Scholar 

  • R.R. Fulthorpe A.N. Rhodes J.M. Tiedje (1998) ArticleTitleHigh levels of endemicity of 3-chlorobenzoate-degrading bacteria Appl. Environ. Microbiol. 64 1620–1627 Occurrence Handle9572926 Occurrence Handle1:CAS:528:DyaK1cXislWmu78%3D

    PubMed  CAS  Google Scholar 

  • M. Goodfellow J.A. Haynes (1984) Actinomycetes in marine sediments L. Ortiz-Ortiz (Eds) Biological, biochemical and biomedical aspects of actinomycetes Academic Press Inc. New York 453–472

    Google Scholar 

  • H.P. Grossart A. Schlingoff M. Bernhard M. Simon T. Brinkhoff (2004) ArticleTitleAntagonistic activity of bacteria isolated from organic aggregates of the German Wadden Sea FEMS Micriobiol. Ecol. 47 387–396 Occurrence Handle1:CAS:528:DC%2BD2cXhslWgurk%3D

    CAS  Google Scholar 

  • A. Hagström T. Pommier F. Rohwer K. Simu W. Stolte D. Svensson U.L. Zweifel (2002) ArticleTitleUse of 16S ribosomal DNA for delineation of marine bacterioplankton species Appl. Environ. Microbiol. 68 2633–3628

    Google Scholar 

  • S.K. Han O.I. Nadashkovskaya V.V. Mikhailov S.B. Kim K.S. Bae (2003) ArticleTitleSalinibacterium amurskyense gen.nov., sp nov., a novel genus of the family Microbacteriaceae from the marine environment Int. J. Syst. Evol. Microbiol. 53 2061–2066 Occurrence Handle14657146 Occurrence Handle1:CAS:528:DC%2BD2cXhtF2msA%3D%3D

    PubMed  CAS  Google Scholar 

  • B.P. Hayden C.G. Ray R. Dolan (1984) ArticleTitleClassification of coastal and marine environments Environ. Conserv. 11 199–207

    Google Scholar 

  • S.C. Heald P.F.B. Brandão R. Hardicre A.T. Bull (2001) ArticleTitlePhysiology, biochemistry and taxonomy of deep-sea nitrile metabolising Rhodococcus strains Antonie van Leeuwenhoek. 80 169–183 Occurrence Handle11759050 Occurrence Handle1:CAS:528:DC%2BD3MXptlGjsL0%3D

    PubMed  CAS  Google Scholar 

  • B.P. Hedlund J.T. Staley (2004 ) Microbial endemism and biogeography A.T. Bull (Eds) Microbial Diversity and Bioprospecting ASM Press Washington, DC 225–231

    Google Scholar 

  • E. Helmke H. Weyland (1984) ArticleTitleRhodococcus marinonascens sp.nov., an actinomycete from the sea Int. J. Syst. Bacteriol. 34 127–138

    Google Scholar 

  • M.C. Horner-Devine K.M. Carney B.J.M. Bohannan (2003) ArticleTitleAn ecological perspective on bacterial diversity Proc. R. Soc. Lond. B. 271 113–122

    Google Scholar 

  • J.B. Hughes J.J. Hellmann T.H. Ricketts B.J.M. Bohannan (2002) ArticleTitleCounting the uncountable: statistical approaches to estimating microbial diversity Appl. Environ. Microbiol. 67 4399–4406

    Google Scholar 

  • F. Inagaki M. Suzuki K. Takai H. Oida T. Sakamoto K. Aoki K.H. Nealson K. Horikoshi (2003) ArticleTitleMicrobial communities associated with geological horizons in coastal subseafloor sediments from the Sea of Okhotsk Appl. Environ. Microbiol. 69 7224–7235 Occurrence Handle14660370 Occurrence Handle1:CAS:528:DC%2BD3sXpvFCls74%3D

    PubMed  CAS  Google Scholar 

  • Jensen P.R., Mincer T.J., Williams P.G. and Fenical W. 2004. Marine actinomycete diversity and natural product discovery. Antonie van Leeuwenhoek 87: 43–48 (This issue).

    Google Scholar 

  • B.S. Kim H.M. Oh H. Kang S.S. Park J. Chun (2004) ArticleTitleRemarkable bacterial diversity in the tidal flat sediment as revealed by 16S rDNA analysis J. Microbiol. Biotechnol. 14 205–211 Occurrence Handle1:CAS:528:DC%2BD2cXislals7k%3D

    CAS  Google Scholar 

  • B.S. Kim J. Lonsdale C.N. Seong M. Goodfellow 2003 Streptacidophilus gen. nov., acidophilic actinomycetes with wall chemotype I and emendation of the family Streptomycetaceae (Waksman and Henrici [1943 al] emend Rainey 1997 Antonie van Leeuwenhoek. 83 107 116

  • B.D. Lanoil R. Sassen M.T. La Duc S.T. Sweet K.H. Nealson (2001) ArticleTitleBacteria and archaea physically associated with Gulf of Mexico gas hydrates Appl. Environ. Microbiol. 67 5143–5153 Occurrence Handle11679338 Occurrence Handle1:CAS:528:DC%2BD3MXotlSnsrg%3D

    PubMed  CAS  Google Scholar 

  • V.M. Madrid J.Y. Aller R.C. Aller A.Y. Chistoserdov (2001) ArticleTitleHigh prokaryote diversity and analysis of community structure in mobile mud off French Guiana: identification of two new bacterial candidate divisions FEMS Microbiol. Ecol. 37 197–209 Occurrence Handle1:CAS:528:DC%2BD3MXovVCju70%3D

    CAS  Google Scholar 

  • Maldonado L.A., Stach J.E.M., Pathom-Aree W., Ward A.C., Bull A.T. and Goodfellow M. 2004a. Diversity of cultivable actinobacteria in geographically widespread marine sediments. Antonie van Leeuwenhoek 87: 11–18 (this issue).

  • Maldonado L.A., Fenical W., Jensen P.R., Kauffman C.A., Mincer T.J., Bull A.T., Ward A.C. and Goodfellow M. 2004b. Salinopsoragen. nov., a home for obligate marine actinomycetes belonging to the family Micromonopsoraceae. Int. J. Syst. Evol. Microbiol. (submitted).

  • V.T. Marteinsson J.-L. Birrien C. Jeanthon D. Prieur (1996) ArticleTitleNumerical taxonomic study of thermophilic Bacillus isolated from three geographically separated deep-sea hydrothermal vents FEMS Microbiol. Ecol. 21 255–266 Occurrence Handle1:CAS:528:DyaK28Xnt1Onu7Y%3D

    CAS  Google Scholar 

  • AP. Martin (2002) ArticleTitlePhylogenetic approaches for describing and comparing the diversity of microbial communities Appl. Environ. Microbiol. 68 3673–2682 Occurrence Handle12147459 Occurrence Handle1:CAS:528:DC%2BD38XmtVaqtLY%3D

    PubMed  CAS  Google Scholar 

  • T.J. Mincer P.R. Jensen C.A. Kauffman W. Fenical (2002) ArticleTitleWidespread and persistent populations of a major new marine actinomycete taxon in ocean sediments Appl. Environ. Microbiol. 68 5005–5011 Occurrence Handle12324350 Occurrence Handle1:CAS:528:DC%2BD38XnvFClurY%3D

    PubMed  CAS  Google Scholar 

  • M.A. Moran L.T. Rutherfford R.E. Hodson (1995) ArticleTitleEvidence for indigenous Streptomyces populations in a marine environment determined with a 16S rRNA probe Appl. Environ. Microbiol. 61 3695–3700 Occurrence Handle7487005 Occurrence Handle1:CAS:528:DyaK2MXosFGms7s%3D

    PubMed  CAS  Google Scholar 

  • G.A. Nesterenko T.M. Nogina E.J. Kasumova S.G. Batrakov (1982) ArticleTitleRhodococcus luteus nom. nov. and Rhodococcus maris nom. nov Int. J. Syst. Bacteriol. 32 1–14

    Google Scholar 

  • T. Oprea (2002) ArticleTitleChemical space navigation in lead discovery Curr. Op. Chem. Biol. 6 384–389 Occurrence Handle1:CAS:528:DC%2BD38XjvVektrg%3D

    CAS  Google Scholar 

  • T. Oprea J. Gottfries (2001) ArticleTitleChemography: the art of navigating in chemical space J. Comb. Chem. 3 157–166 Occurrence Handle11300855 Occurrence Handle1:CAS:528:DC%2BD3MXhtFams78%3D

    PubMed  CAS  Google Scholar 

  • T. Palys L.K Nakamura F.M. Cohan (1997) ArticleTitleDiscovery and classification of ecological diversity in the bacterial world: the role of DNA sequence data Int. J. Syst. Bacteriol. 47 1145–1156 Occurrence Handle9336922 Occurrence Handle1:CAS:528:DyaK2sXntV2qurg%3D

    PubMed  CAS  Google Scholar 

  • R.T. Papke N.B Ramsing M.M. Bateson D.M. Ward (2003) ArticleTitleGeographical isolation in hot spring cyanobacteria Environ. Microbiol. 5 650–659 Occurrence Handle12871232 Occurrence Handle1:CAS:528:DC%2BD3sXntFyqsbc%3D

    PubMed  CAS  Google Scholar 

  • R.J. Parkes P. Wellsbury (2004) Deep biospheres A.T. Bull (Eds) Microbial Diversity and Bioprospecting ASM Press Washington, DC 120–129

    Google Scholar 

  • J. Peplies S.C.K. Lau J. Pernthaler R Amann F.O. Glockner (2004) ArticleTitleApplication and validation of microarrays for the 16S rRNA-based analysis of marine bacterioplankton Environ. Microbiol. 6 638–645 Occurrence Handle15142252 Occurrence Handle1:CAS:528:DC%2BD2cXlsVSmtrs%3D

    PubMed  CAS  Google Scholar 

  • N. Posedel J. Faganeli (1991) ArticleTitleNature and sedimentation of suspended particulate matter during density stratification in shallow coastal waters (Gulf of Trieste northern Adriatic) Mar. Ecol. Prog. Ser. 77 135–145

    Google Scholar 

  • S. Radajewski P. Ineson N.R. Parekh J.C. Murrell (2000) ArticleTitleStable-isotope probing as a tool in microbial ecology Nature 403 646–649 Occurrence Handle10.1038/35001054 Occurrence Handle1:CAS:528:DC%2BD3cXht1Oqt7w%3D Occurrence Handle10688198

    Article  CAS  PubMed  Google Scholar 

  • F.A. Rainey J. Burghardt R.M. Kroppenstedt S. Klatte E. Stackebrandt (1995) ArticleTitlePhylogenetic analysis of the genera Rhodococcus Nocardia evidence for the evolutionary origin of the genus Nocardia from within the radiation of Rhodococcus species Microbiol-UK. 141 523–528 Occurrence Handle10.1099/13500872-141-2-523 Occurrence Handle1:CAS:528:DyaK2MXjvVWqtbo%3D

    Article  CAS  Google Scholar 

  • M.S. Rappe D.A. Gordon K.L. Vergin S.J. Giovannoni (1999) ArticleTitlePhylogeny of actinobacteria small subunit (SSU) rRNA gene clones recovered from marine bacterioplankton Syst. Appl. Microbiol. 22 106–112

    Google Scholar 

  • D.W. Reed Y. Fujita M.E. Delwiche D.B. Blackwelder P.P. Sheridan Uchida T. F.S. Colwell (2002) ArticleTitleMicrobial communities from methane hydrate-bearing deep marine sediments in a forearc basin Appl. Environ. Microbiol. 68 3759–3770 Occurrence Handle12147470 Occurrence Handle1:CAS:528:DC%2BD38XmtVaqtbc%3D

    PubMed  CAS  Google Scholar 

  • J. Riedlinger A. Reicke B. Krismer H. Zähner A.T. Bull L.A Maldonado M. Goodfellow B. Bister D. Bischoff R.D. Süssmuth H.-P. Fiedler (2004) ArticleTitleAbyssomicins, inhibitors of para-aminobenzoic acid pathway produced by the marine Verrucosispora strain AB-18–032 J. Antibiot. 57 271–279 Occurrence Handle15217192 Occurrence Handle1:CAS:528:DC%2BD2cXjslCgs70%3D

    PubMed  CAS  Google Scholar 

  • M.S. Roberts F.M. Cohan (1995) ArticleTitleRecombination and migration rates in natural populations of Bacillus subtilis Bacillus mojavensis Evol. 49 1081–1094

    Google Scholar 

  • C.E. Salomon N.A. Margarvey D.H. Sherman (2004) ArticleTitleMerging the potential of microbial genetics with biological and chemical diversity: an even brighter future for marine natural product drug discovery Nat. Prod. Rep. 21 105–121 Occurrence Handle15039838 Occurrence Handle1:CAS:528:DC%2BD2cXisFWgtLc%3D

    PubMed  CAS  Google Scholar 

  • R.K. Scott (2002) ArticleTitleChemical space in In Silico screening Screening 4 32–34

    Google Scholar 

  • V. Souza T.T. Nguyen R.R. Hudson D. Piero R.E. Lenski (1992) ArticleTitleHierarchical analysis of linkage diequilibrium in rhizobium populations: evidence for sex Proc. Natl. Acad. Sci. USA. 89 8389–8393 Occurrence Handle1518873 Occurrence Handle1:STN:280:DyaK38zptVCmsQ%3D%3D

    PubMed  CAS  Google Scholar 

  • Stach J.E.M. and Bull A.T. 2004. Estimating and comparing the diversity of marine actinobacteria. Antonie van Leeuwenhoek. 87: 3–9 (this issue).

    Google Scholar 

  • J.E.M. Stach L.A. Maldonado D.G. Masson A.C. Ward M. Goodfellow A.T. Bull (2003a) ArticleTitleStatistical approaches to estimating bacterial diversity in marine sediments Appl. Environ. Microbiol. 69 6189–6200 Occurrence Handle1:CAS:528:DC%2BD3sXotlKjsLo%3D

    CAS  Google Scholar 

  • J.E.M. Stach L.A. Maldonado A.C. Ward M. Goodfellow A.T. Bull (2003b) ArticleTitleNew primers specific for taxa assigned to the class Actinobacteria: application to marine and terrestrial environments Environ. Microbiol. 5 828–841 Occurrence Handle1:CAS:528:DC%2BD3sXos1Clt7c%3D

    CAS  Google Scholar 

  • E. Stackebrandt F.A. Rainey N.L. Ward-Rainey (1997) ArticleTitleProposal for a new hierarchic classification systemActinobacteria classis nov Int. J. Syst. Bacteriol. 47 479–491 Occurrence Handle10.1099/00207713-47-2-479

    Article  Google Scholar 

  • J.T. Staley (2004) Speciation and bacterial phylospecies A.T. Bull (Eds) Microbial Diversity and Bioprospecting ASM Press Washington, DC 40–48

    Google Scholar 

  • J.T. Staley J.J. Gosink (1999) ArticleTitlePoles apart: biodiversity and biogeography of sea ice bacteria Annu. Rev. Microbiol. 53 189–215 Occurrence Handle10547690 Occurrence Handle1:CAS:528:DyaK1MXmvVOnsLg%3D

    PubMed  CAS  Google Scholar 

  • O.C. Stine A. Carnahan R. Singh J. Powell J.P. Furuno A. Dorsey E. Silbergeld N.H. Williams J.G. Morris (2003) ArticleTitleCharacterization of microbial communities from coastal waters using microarrays Environ. Monitor. Assess. 81 327–336 Occurrence Handle1:CAS:528:DC%2BD38XptFKgur0%3D

    CAS  Google Scholar 

  • W.R. Strohl (2004) Antimicrobials A.T. Bull (Eds) Microbial Diversity and Bioprospecting ASM Press Washington, DC 336–355

    Google Scholar 

  • C. Syldatk P.F.B. Brandao A.T. Bull S. Verseck J. Erfurth S. Buchholz S. Oβ wald K. Drauz 2003 Nitrile hydratases from Rhodococcus erythropolis their application 1 72 European Patent Application No. 03 001 725.6 [27.01.2003]

  • H. Takami A. Inoue F. Fuji K. Horikoshi (1997) ArticleTitleMicrobial flora in the deepest sea mud of the Mariana Trench FEMS Microbiol. Lett. 152 279–285 Occurrence Handle9231422 Occurrence Handle1:CAS:528:DyaK2sXks12htLk%3D

    PubMed  CAS  Google Scholar 

  • M. Takizawa R.R. Colwell R.T. Hill (1993) ArticleTitleIsolation and diversity of actinomycetes in the Chesapeake Bay Appl. Environ. Microbiol. 59 997–1002 Occurrence Handle16348922 Occurrence Handle1:STN:280:DC%2BC3crot1ehsQ%3D%3D

    PubMed  CAS  Google Scholar 

  • C. Turley (2000) ArticleTitleBacteria in the cold deep-sea benthic boundary layer and sediment-water interface of the NE Atlantic FEMS Microbiol. Ecol. 33 89–99 Occurrence Handle10967208 Occurrence Handle1:CAS:528:DC%2BD3cXmtVCrurs%3D

    PubMed  CAS  Google Scholar 

  • A.C. Ward M. Goodfellow (2004) Phylogeny and functionality: taxonomy as a roadmap to genes A.T. Bull (Eds) Microbial Diversity and Bioprospecting. ASM Press Washington, DC 288–313

    Google Scholar 

  • F. Warnecke R. Amann J. Pernthaler (2004) ArticleTitleActinobacterial 16S rRNA genes from freshwater habitats cluster in four distinct lineages Environ. Microbiol. 6 242–253 Occurrence Handle14871208 Occurrence Handle1:CAS:528:DC%2BD2cXitlOhtbc%3D

    PubMed  CAS  Google Scholar 

  • M.G. Watve R. Tickoo M.M. Jog B.D. Bhole (2001) ArticleTitleHow many antibiotics are produced by the genus Streptomyces? Arch. Microbiol. 176 386–390 Occurrence Handle11702082 Occurrence Handle1:CAS:528:DC%2BD3MXptVeitb0%3D

    PubMed  CAS  Google Scholar 

  • H. Weyland (1969) ArticleTitleActinomycetes in North Sea and Atlantic Ocean sediments Nature 223 858 Occurrence Handle5799036 Occurrence Handle1:STN:280:DyaF1M3lt1Kiug%3D%3D

    PubMed  CAS  Google Scholar 

  • H. Weyland (1981) ArticleTitleDistribution of actinomycetes on the sea floor Zentralbl. Bakteriol. Parasitenkd. Infektionskr. Hyg. Abt. 1 309–314

    Google Scholar 

  • R.J. Whitaker D.W. Grogan J.T. Taylor (2003) ArticleTitleGeographic barriers isolate endemic populations of hyperthermophilic archaea Science 301 976–978 Occurrence Handle10.1126/science.1086909 Occurrence Handle1:CAS:528:DC%2BD3sXmt1elsLc%3D Occurrence Handle12881573

    Article  CAS  PubMed  Google Scholar 

  • E. Zazopoulos K.X. Huang W. Liu B.O. Bachmann K Nonaka J. Ahlert J.S. Thorson B. Shen C.M. Farnet (2003) ArticleTitleA genomics-guided approach for discovering and expressing cryptic metabolic pathways Nat. Biotechnol. 21 187–190 Occurrence Handle12536216 Occurrence Handle1:CAS:528:DC%2BD3sXnsFWhsg%3D%3D

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Research School of Biosciences, University of Kent, CT2 7NJ, Canterbury, Kent

    Alan T Bull & James E.M Stach

  2. School of Biology, University of Newcastle, NE1 7RU, Newcastle upon Tyne, United Kingdom

    Alan T Bull, James E.M Stach, Alan C Ward & Michael Goodfellow

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  1. Alan T Bull
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Bull, A.T., Stach, J. ., Ward, A.C. et al. Marine actinobacteria: perspectives, challenges, future directions. Antonie Van Leeuwenhoek 87, 65–79 (2005). https://doi.org/10.1007/s10482-004-6562-8

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