Abstract
HIV continues to be a public health issue for older adults. Previous studies have examined predictors of quality of life (QoL) among people living with HIV (PLWH), but the majority have been in international settings and have not focused on older adults living with HIV (OALH). The aim of this study was to examine the associations between psychosocial protective and risk factors (resilience, internalized HIV-related stigma, and depression), and overall and domains (physical, psychological, independence, social, environmental, and spiritual) of QoL among OALH. Data were obtained from 156 OALH living in South Carolina. Resilience was positively associated with all QoL domains except the spiritual domain. Internalized HIV-related stigma was associated with all QoL domains except the psychological and environmental domains. Depression was associated with the overall QoL measure and all domains. Interventions aimed at increasing resilience, attenuating internalized HIV-related stigma and depressive symptoms may be warranted for OALH, which may improve overall and varying domains of QoL.
Similar content being viewed by others
Data Availability
Data can be obtained by e-mailing Dr. Xiaoming Li (xiaoming@mailbox.sc.edu).
Code Availability
Codes can be obtained by e-mailing Dr. Monique J. Brown (brownm68@mailbox.sc.edu).
References
UNAIDS. Global HIV & AIDS Statistics - Fact Sheet 2022. https://www.unaids.org/en/resources/fact-sheet.
Centers for Disease Control and Prevention. Statistics Overview: HIV Surveillance Report 2022. https://www.cdc.gov/hiv/statistics/overview/index.html.
Centers for Disease Control and Prevention. HIV by Age: HIV Diagnoses 2022. https://www.cdc.gov/hiv/group/age/diagnoses.html.
National Institutes of Health. HIV and Older People 2018. https://hivinfo.nih.gov/understanding-hiv/fact-sheets/hiv-and-older-people#:~:text=Key%20Points,to%20get%20tested%20for%20HIV.
United States Census Bureau. American Community Survey 2022. https://data.census.gov/cedsci/table?tid=ACSST1Y2021.S0101.
Hudelson C, Cluver L. Factors associated with adherence to antiretroviral therapy among adolescents living with HIV/AIDS in low- and middle-income countries: a systematic review. AIDS Care. 2015;27(7):805–16.
World Health Organization. WHOQOL: Measuring Quality of Life 2022. https://www.who.int/tools/whoqol.
World Health Organization. WHOQOL-HIV-BREF, 2012 Revision 2022. https://apps.who.int/iris/handle/10665/77775.
Shriharsha C, Rentala S. Quality of life among people living with HIV/AIDS and its predictors: a cross-sectional study at ART center, Bagalkot, Karnataka. J Fam Med Prim Care. 2019;8(3):1011–6.
Khademi N, Zanganeh A, Saeidi S, Teimouri R, Khezeli M, Jamshidi B, et al. Quality of life of HIV-infected individuals: insights from a study of patients in Kermanshah, Iran. BMC Infect Dis. 2021;21(1):203.
Catalan J, Tuffrey V, Ridge D, Rosenfeld D. What influences quality of life in older people living with HIV? AIDS Res Ther. 2017;14:22.
Yoo-Jeong M, Nguyen AL, Waldrop D. Social network size and its relationship to domains of quality-of-life among older persons living with HIV. AIDS Care. 2022. https://doi.org/10.1080/09540121.2022.2057907.
Brown MJ, Harrison SE, Li X. Gender disparities in traumatic life experiences and antiretroviral therapy adherence among people living with HIV in South Carolina. AIDS Behav. 2019;23:2904–15.
Brown MJ, Trask JS, Zhang J, Haider MR, Li X. Sociodemographic and psychosocial correlates of resilience among older adults living with HIV in the Deep South. J Health Psychol. 2021;26(11):2010–9.
Campbell-Sills L, Stein MB. Psychometric analysis and refinement of the Connor-davidson Resilience Scale (CD-RISC): validation of a 10-item measure of resilience. J Trauma Stress. 2007;20(6):1019–28.
Berger BE, Ferrans CE, Lashley FR. Measuring stigma in people with HIV: psychometric assessment of the HIV stigma scale. Res Nurs Health. 2001;24(6):518–29.
Reinius M, Wettergren L, Wiklander M, Svedhem V, Ekstrom AM, Eriksson LE. Development of a 12-item short version of the HIV stigma scale. Health Qual Life Outcomes. 2017;15(1):115.
Kroenke K, Spitzer RL. The PHQ-9: a new depression diagnostic and severity measure. Psychiatr Ann. 2002;32(9):1–7.
Kroenke K, Spitzer RL, Williams JB. The PHQ-9: validity of a brief depression severity measure. J Gen Intern Med. 2001;16(9):606–13.
Campos AC, Ferreira e Ferreira E, Vargas AM, Albala C. Aging, Gender and Quality of Life (AGEQOL) study: factors associated with good quality of life in older Brazilian community-dwelling adults. Health Qual Life Outcomes. 2014;12:166.
Brett CE, Dykiert D, Starr JM, Deary IJ. Predicting change in quality of life from age 79 to 90 in the Lothian Birth Cohort 1921. Qual Life Res. 2019;28(3):737–49.
Kim HJ, Jen S, Fredriksen-Goldsen KI. Race/ethnicity and health-related quality of life among LGBT older adults. Gerontologist. 2017;57(suppl 1):S30–9.
Bouwmans C, de Sonneville C, Mulder CL, Hakkaart-van RL. Employment and the associated impact on quality of life in people diagnosed with schizophrenia. Neuropsychiatr Dis Treat. 2015;11:2125–42.
Kober R, Eggleton IR. The effect of different types of employment on quality of life. J Intellect Disabil Res. 2005;49(Pt 10):756–60.
Ramos de Lima LF, Volpe C, Santos S, Funez M, Stival M. Quality of life and time since diagnosis of diabetes mellitus among the elderly. Rev Bras Geriatr Gerontol. 2018;21(2):176–85.
Forster AS, Herbert A, Koo MM, Taylor RM, Gibson F, Whelan JS, et al. Associations between diagnostic time intervals and health-related quality of life, clinical anxiety and depression in adolescents and young adults with cancer: cross-sectional analysis of the BRIGHTLIGHT cohort. Br J Cancer. 2022;126(12):1725–34.
Miller KA, Stal J, Gallagher P, Weng Z, Freyer DR, Kaslander JN, et al. Time from diagnosis and correlates of health-related quality of life among young adult colorectal cancer survivors. Cancers (Basel). 2021;13(16):4045.
Geary C, Parker W, Rogers S, Haney E, Njihia C, Haile A, et al. Gender differences in HIV disclosure, stigma, and perceptions of health. AIDS Care. 2014;26(11):1419–25.
Mugoya GC, Ernst K. Gender differences in HIV-related stigma in Kenya. AIDS Care. 2014;26(2):206–13.
Rivera AV, DeCuir J, Crawford ND, Amesty S, Harripersaud K, Lewis CF. Factors associated with HIV stigma and the impact of a nonrandomized multi-component video aimed at reducing HIV stigma among a high-risk population in New York City. AIDS Care. 2015;27(6):772–6.
Zhang C, Li X, Liu Y, Qiao S, Zhou Y, Shen Z, et al. Substance use and psychosocial status among people living with HIV/AIDS who encountered HIV stigma in China: stratified analyses by socio-economic status. PLoS ONE. 2016;11(11): e0165624.
Galvan FH, Davis EM, Banks D, Bing EG. HIV stigma and social support among African Americans. AIDS Patient Care STDS. 2008;22(5):423–36.
Rao D, Pryor JB, Gaddist BW, Mayer R. Stigma, secrecy, and discrimination: ethnic/racial differences in the concerns of people living with HIV/AIDS. AIDS Behav. 2008;12(2):265–71.
Brown MJ, Hill NL, Haider MR. Age and gender disparities in depression and subjective cognitive decline-related outcomes. Aging Ment Health. 2022;26(1):48–55.
Bhatia R, Hartman C, Kallen MA, Graham J, Giordano TP. Persons newly diagnosed with HIV infection are at high risk for depression and poor linkage to care: results from the Steps Study. AIDS Behav. 2011;15(6):1161–70.
De Brito HLS, Maria E, Seidl F. Resilience of people with HIV/AIDS: Influence of religious coping. Trends Pyschol. 2019;27(3):647–60.
Fang X, Vincent W, Calabrese SK, Heckman TG, Sikkema KJ, Humphries DL, et al. Resilience, stress, and life quality in older adults living with HIV/AIDS. Aging Ment Health. 2015;19(11):1015–21.
Dewi DH. The relationship between spirituality, quality of life, and resilience. Adv Soc Sci Educ Hum Res. 2019;349:145–7.
American Psychological Association. Resilience 2022. https://www.apa.org/topics/resilience.
Dolcos F, Hohl K, Hu Y, Dolcos S. Religiosity and resilience: cognitive reappraisal and coping self-efficacy mediate the link between religious coping and well-being. J Relig Health. 2021;60(4):2892–905.
Shiharsha CR. Resilience and quality of life of people living with HIV/AIDS. A cross sectional study at ART centre, Bagalkot, Karnataka. Indian J Public Health Res Dev. 2020;11(7):1016–22.
Wen J, Yeh TP, Xie H, Yu X, Tang J, Chen Y. Resilience, self-esteem, self-efficacy, social support, depression and ART adherence among people living with HIV in Sichuan, China. AIDS Care. 2021;33(11):1414–21.
van der Kooij YL, Kupková A, den Daas C, van den Berk GEL, Kleene MJT, Jansen HSE, et al. Role of self-stigma in pathways from HIV-related stigma to quality of life among people living with HIV. AIDS Patient Care STDS. 2021;35(6):231–8.
Tavakol M, Dennick R. Making sense of Cronbach’s alpha. Int J Med Educ. 2011;2:53–5.
Acknowledgements
We would like to thank the clinic staff for helping with recruitment and the participants for participating in the study.
Funding
This study was funded by the South Carolina SmartState Program®. M. J. Brown is supported by grant K01MH115794 from the National Institute of Mental Health. The sponsors had no role in the design, analysis or decision to publish these findings. The content is solely the responsibility of the authors and does not necessarily represent the official views of the South Carolina SmartState Program® or the National Institutes of Health.
Author information
Authors and Affiliations
Contributions
MJB conceived the paper, designed the study and analyzed the data. MJB and DA wrote the first draft of the paper. All authors commented on previous versions of the manuscript.
Corresponding author
Ethics declarations
Conflict of interest
There are no conflicts of interest to disclose for any author.
Ethical Approval
The study was approved by the University of South Carolina Institutional Review Board.
Consent to Participate
All participants provided informed consent to participate before participating in the study.
Consent for Publication
Participants provided consent to publishing study results.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
About this article
Cite this article
Brown, M.J., Amoatika, D., Kaur, A. et al. Psychosocial Protective and Risk Factors of Quality of Life Outcomes Among Older Adults Living With HIV. AIDS Behav 27, 2642–2648 (2023). https://doi.org/10.1007/s10461-023-03989-2
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10461-023-03989-2