Abstract
Little is known about the impact of early palliative care (EPC) combined with motivational interviewing (MI) for persons living with AIDS (PWA). We compared the cost and quality-adjusted life-years (QALYs) of EPC + MI (n = 61) versus usual care (UC) (n = 60) for patients with AIDS, not on antiretroviral medications, enrolled into the Living Well Project trial. Data on clinic, emergency department, and hospital visits were collected through self-report and billing records. Risk-adjusted average annual health care costs were estimated using a generalized linear model with a gamma log-link function. QALYs were calculated using the SF-12v2. Cost-effectiveness was defined as cost per QALY gained. Estimated intervention costs were $165 per participant. EPC + MI reduced costs by 33% (AOR = 0.67; CI 95%: 0.15, 0.93). QALYs did not differ between groups. Results suggest EPC + MI for PWA is cost-saving and maintains quality of life compared to UC due to reduced hospital and ED costs.
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Funding
This research was funded by NINR/NIH R01NR014054 (PIs Holstad, M & Quest, T), and received partial support by the Emory Center for AIDS Research (P30AI050409). This clinical trial is registered at ClinicalTrials.gov number NCT01848483.
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Victoria Phillips: Study design, data collection, data analysis, writing of manuscript. Tammie E. Quest, MD: Project Co-Pi, assistance with data interpretation and writing of manuscript. Melinda Higgins: assistance with data collection and data analysis. Vincent C. Marconi, MD: Project Co-Pi, assistance with data interpretation and writing of manuscript. Monique S. Balthazar, DNP, PhD, FNP-BC, AGACNP-BC: assistance with data collection and writing of manuscript. Marcia Holstad, PhD, FNP-BC6: Project PI, study design, data collection and writing of manuscript.
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Phillips, V., Quest, T.E., Higgins, M. et al. A Cost-Effective Analysis of Motivational Interviewing with Palliative Care Versus Usual Care: Results from the Living Well Project. AIDS Behav 27, 1259–1268 (2023). https://doi.org/10.1007/s10461-022-03862-8
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DOI: https://doi.org/10.1007/s10461-022-03862-8