Skip to main content

Advertisement

Log in

Social and Structural Factors Associated with Sustained Viral Suppression Among Heterosexual Black Men with Diagnosed HIV in the United States, 2015–2017

  • Original Paper
  • Published:
AIDS and Behavior Aims and scope Submit manuscript

Abstract

This paper describes sociodemographic, sexual risk behavior, and clinical care factors associated with sustained viral suppression (SVS) among heterosexual Black men with diagnosed HIV in the US. Sample was 968 men, 2015–2017 cycles of Medical Monitoring Project. We used prevalence ratios and a multivariable logistic regression model to identify independent predictors of SVS. About 9% of sexually active men had sex that carries a risk of HIV transmission. Nearly 2/3 lived at or below the poverty level, 13% were under or uninsured, 1/4 experienced food insecurity and 15% reported recent homelessness. About 26% were not engaged in HIV care, 8% not currently taking antiretroviral therapy (ART) and 59% had SVS. Among men taking ART, care engagement and adherence were the only significant independent predictors of SVS. Efforts to increase VS should focus on increasing ART use, care engagement, and ART adherence, and include strategies that address the social and structural factors that influence them.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Centers for Disease Control and Prevention. HIV Surveillance Report, 2017, vol. 29. https://www.cdc.gov/hiv/library/reports/hiv-surveillance.html. Published November 2018. Accessed 22 April 2019.

  2. Cohen MS, Chen YQ, McCauley M, et al. Prevention of HIV-1 infection with early antiretroviral therapy. N Engl J Med. 2011;365:493–505.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Cohen MS, Chen YQ, McCauley M, et al. Antiretroviral therapy for the prevention of HIV-1 transmission. N Engl J Med. 2016;375:830–9.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  4. Li Z, Purcell DW, Sansom SL, Hayes D, Hall HI. Vital Signs: HIV transmission along the continuum of care—United States, 2016. Morb Mortal Wkly Rep. 2019;68:267–72. https://doi.org/10.15585/mmwr.mm6811e1.

  5. Centers for Disease Control and Prevention. Monitoring selected national HIV prevention and care objectives by using HIV surveillance data—United States and 6 dependent areas, 2016. HIV Surveillance Supplemental Report 2018; 23 (No. 4). https://www.cdc.gov/hiv/library/reports/hiv-surveillance.html. Published June 2018. Accessed 21 June 2019.

  6. Aidala AA, Wilson MG, Shubert V, et al. Housing status, medical care, and health outcomes among people living with HIV/AIDS: a systematic review. Am J Public Health. 2016;106(1):e1–23.

    Article  PubMed  PubMed Central  Google Scholar 

  7. Feller DJ, Agins BD. Understanding determinants of racial and ethnic disparities in viral load suppression. J Int Assoc Provid AIDS Care. 2017;16(1):23–9.

    Article  PubMed  Google Scholar 

  8. Palepu A, Milloy MJ, Kerr T, Zhang R, Wood E. Homelessness and adherence to antiretroviral therapy among a cohort of HIV infected injection drug users. J Urban Health. 2011;88(3):545–55.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Joseph B, Kerr T, Puskas CM, Montaner J, Wood E, Milloy MJ. Factors linked to transitions in adherence to antiretroviral therapy among HIV-infected illicit drug users in a Canadian setting. AIDS Care. 2015;27(9):1128–36.

    Article  PubMed  PubMed Central  Google Scholar 

  10. Small W, Wood E, Betteridge G, Montaner J, Kerr T. The impact of incarceration upon adherence to HIV treatment among HIV-positive injection drug users: a qualitative study. AIDS Care. 2009;21(6):708–14.

    Article  PubMed  Google Scholar 

  11. Weiser SD, Hatcher A, Frongillo EA, et al. Food insecurity is associated with greater acute care utilization among HIV-infected homeless and marginally housed individuals in San Francisco. J Gen Intern Med. 2012;28(1):91–8.

    Article  PubMed  PubMed Central  Google Scholar 

  12. Robbins GK, Daniels B, Zheng H, et al. Predictors of antiretroviral treatment failure in an urban HIV clinic. J Acquir Immune Defic Syndr. 2007;44(1):30–7.

    Article  PubMed  PubMed Central  Google Scholar 

  13. Pence BW. The impact of mental health and traumatic life experiences on antiretroviral treatment outcomes for people living with HIV/AIDS. J Antimicrob Chemother. 2009;63(4):636–40.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  14. Whetten K, Reif S, Whetten R, Murphy-McMillan LK. Trauma, mental health, distrust, and stigma among HIV-positive persons: implications for effective care. Psychosom Med. 2008;70(5):531–8.

    Article  PubMed  Google Scholar 

  15. Pence BS, Miller WC, Gaynes BN, Eron JJ Jr. Psychiatric illness and virologic response in patients initiating Highly Active Antiretroviral Therapy. J Acquir Immune Defic Syndr. 2007;44(2):159–66.

    Article  PubMed  Google Scholar 

  16. Fauci AS, Redfield RR, Sigounas G, Weahkee MD, Giroir BP. Ending the HIV epidemic A plan for the United States. JAMA. 2019;321(9):844–5. https://doi.org/10.1001/jama.2019.1343.

    Article  PubMed  Google Scholar 

  17. Heeringa S, West BT, Berglund PA. Applied survey data analysis. Boca Raton: Taylor and Francis; 2010.

    Book  Google Scholar 

  18. U.S. Department of Health and Human Services. 2015 Poverty guidelines. https://aspe.hhs.gov/2015-poverty-guidelines. Published 2015. Accessed 21 June 2019

  19. Kroenke K, Strine TW, Spitzer RL, Williams JB, Berry JT, Mokdad AH. The PHQ-8 as a measure of current depression in the general population. J Affect Disord. 2009;114:163–73.

    Article  PubMed  Google Scholar 

  20. Wright K, Naar-King S, Lam P, Templin T, Frey M. Stigma scale revised: reliability and validity of a brief measure of stigma for HIV+ youth. J Adolesc Health. 2007;40:96–8.

    Article  PubMed  Google Scholar 

  21. Centers for Disease Control and Prevention. Revised surveillance case definition for HIV infection—United States, 2014 MMWR recommendations and reports. Morb Mortal Wkly Rep Recomm Rep/Cent Dis Control. 2014;63:1–10.

    Google Scholar 

  22. Wilson IB, Lee Y, Michaud J, Fowler FJ Jr, Rogers WH. Validation of a new three-item self-report measure for medication adherence. AIDS Behav. 2016;20:2700–8.

    Article  PubMed  PubMed Central  Google Scholar 

  23. Chou R, Evans C, Hoverman A, et al. Preexposure prophylaxis for the prevention of HIV infection: evidence report and systematic review for the US Preventive Services Task Force. JAMA. 2019;321:2214–30.

    Article  PubMed  Google Scholar 

  24. Rodger AJ, Cambiano V, Bruun T, et al. Risk of HIV transmission through condomless sex in serodifferent gay couples with the HIV-positive partner taking suppressive antiretroviral therapy (PARTNER): final results of a multicentre, prospective, observational study. Lancet. 2019. https://doi.org/10.1016/S0140-6736(19)30418-0.

    Article  PubMed  PubMed Central  Google Scholar 

  25. Weller SC, Davis-Beaty K. Condom effectiveness in reducing heterosexual HIV transmission. Cochrane Database Syst Rev. 2001;(3), Art. No. CD003255. https://doi.org/10.1002/14651858.CD003255.

  26. Young S, Wheeler AC, McCoy SI, Weiser SD. A review of the role of food insecurity in adherence to care and treatment among adult and pediatric populations living with HIV and AIDS. AIDS Behav. 2014;8(Suppl 5):8505–15.

    Google Scholar 

  27. Iroh PA, Mayo H, Nijhawan AE. The HIV care cascade before, during and after incarceration: a systematic review and data synthesis. Am J Public Health. 2015;105(7):e5–16.

    Article  PubMed  PubMed Central  Google Scholar 

  28. Meyer JP, Cepeda J, Wu J, Trestman RL, Altice FL, Springer SA. Optimization of human immunodeficiency virus treatment during incarceration: a viral suppression at the prison gate. JAMA Intern Med. 2014;174(5):721–9.

    Article  PubMed  PubMed Central  Google Scholar 

  29. Meyer JP, Cepeda J, Springer SA, Wu J, Trestman RL, Altice FL. HIV in people reincarcerated in Connecticut prisons and jails: an observational cohort study. Lancet HIV. 2014;1(2):e77–84.

    Article  PubMed  PubMed Central  Google Scholar 

  30. Wohl DA, Golin CE, Knight K, et al. Randomized controlled trial of an intervention to maintain suppression of HIV viremia after prison release: the imPACT trial. J Acquir Immune Defic Syndr. 2017;75(1):81–90.

    Article  PubMed  PubMed Central  Google Scholar 

  31. Althoff AL, Zelenev A, Meyer JP, et al. Correlates of retention in HIV care after release from jail: results from a multi-site study. AIDS Behav. 2013;17(2):156–70.

    Article  PubMed Central  Google Scholar 

  32. Haley DR, Golin CE, Farel CE, et al. Multilevel challenges to engagement in HIV care after prison release: a theory-informed qualitative study comparing prisoners’ perspectives before and after community reentry. BMC Public Health. 2014;14:1253.

    Article  PubMed  PubMed Central  Google Scholar 

  33. Dennis AC, Barrington C, Hino S, Gould M, Wohl D, Golin CE. “You’re in a world of chaos”: experiences accessing HIV care and adhering to medications after incarceration. J Assoc Nurses AIDS Care. 2015;26(5):542–55.

    Article  PubMed  PubMed Central  Google Scholar 

  34. Loeliger KB, Altice FL, Desai MM, Ciarleglio MM, Gallaher C, Meyer JP. Predicators of linkage to HIV care and viral suppression after release from jails and prisons: a retrospective cohort study. Lancet HIV. 2018;5(2):e96–106.

    Article  PubMed  Google Scholar 

  35. Booker CA, Flygare CT, Solomon L, et al. Linkage to HIV care for jail detainees: findings from detention to the first 30 days after release. AIDS Behav. 2013;17(Suppl 2):S128–36.

    Article  PubMed  Google Scholar 

  36. Beer L, McCree DH, Jeffries WL, Lemon A, Sionean C. A review of recent Centers for Disease Control and Prevention activities to reduce HIV stigma in the United States. J Int Assoc Provid AIDS Care. 2019;18:1–5.

    Article  Google Scholar 

  37. Krist AH, Davidson KW, Ngo-Metzger Q. What evidence do we need before recommending routine screening for social determinants of health. Am Fam Physician. 2019;99(10):602–5.

    Google Scholar 

  38. Silverman K, Holtyn A, Rodewald AM, et al. Incentives for viral suppression in people living with HIV; a randomized clinical trial. AIDS Behav. 2019;23:2337–466. https://doi.org/10.1007/s10461-019-02592-8.

    Article  PubMed  Google Scholar 

Download references

Acknowledgements

We thank MMP participants, project area staff, and Provider and Community Advisory Board members. We also acknowledge the contributions of the Clinical Outcomes Team and Behavioral and Clinical Surveillance Branch at the Centers for Disease Control and Prevention.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Donna Hubbard McCree.

Ethics declarations

Conflicts of interest

There are none to declare.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Disclaimer The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

McCree, D.H., Beer, L., Fugerson, A.G. et al. Social and Structural Factors Associated with Sustained Viral Suppression Among Heterosexual Black Men with Diagnosed HIV in the United States, 2015–2017. AIDS Behav 24, 2451–2460 (2020). https://doi.org/10.1007/s10461-020-02805-5

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10461-020-02805-5

Keywords

Navigation