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Load-Based Lower Neck Injury Criteria for Females from Rear Impact from Cadaver Experiments

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Abstract

The objectives of this study were to derive lower neck injury metrics/criteria and injury risk curves for the force, moment, and interaction criterion in rear impacts for females. Biomechanical data were obtained from previous intact and isolated post mortem human subjects and head–neck complexes subjected to posteroanterior accelerative loading. Censored data were used in the survival analysis model. The primary shear force, sagittal bending moment, and interaction (lower neck injury criterion, LNic) metrics were significant predictors of injury. The most optimal distribution was selected (Weibulll, log normal, or log logistic) using the Akaike information criterion according to the latest ISO recommendations for deriving risk curves. The Kolmogorov–Smirnov test was used to quantify robustness of the assumed parametric model. The intercepts for the interaction index were extracted from the primary risk curves. Normalized confidence interval sizes (NCIS) were reported at discrete probability levels, along with the risk curves and 95% confidence intervals. The mean force of 214 N, moment of 54 Nm, and 0.89 LNic were associated with a five percent probability of injury. The NCIS for these metrics were 0.90, 0.95, and 0.85. These preliminary results can be used as a first step in the definition of lower neck injury criteria for women under posteroanterior accelerative loading in crashworthiness evaluations.

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References

  1. AIS. In: The Abbreviated Injury Scale, edited by AAAM. Arlington Heights, IL: American Association for Automotive Medicine, 2005.

    Google Scholar 

  2. Bland, J. M., and D. G. Altman. Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1:307–310, 1986.

    Article  CAS  PubMed  Google Scholar 

  3. Chapline, J. F., S. A. Ferguson, R. P. Lillis, A. K. Lund, and A. F. Williams. Neck pain and head restraint position relative to the driver’s head in rear-end collisions. Accid. Anal. Prev. 32:287–297, 2000.

    Article  CAS  PubMed  Google Scholar 

  4. Cusick, J. F., F. A. Pintar, and N. Yoganandan. Whiplash syndrome: kinematic factors influencing pain patterns. Spine (Phila Pa 1976) 26:1252–1258, 2001.

    Article  CAS  Google Scholar 

  5. FAA. Federal Aviation Administration Advisory Circular 25.562-1B. Dynamic Evaluation of Seat Restraint Systems and Occupant Protection on Transport Airplanes. Washington, DC: Federal Aviation Administration, 2006.

  6. FMVSS-208. FMVSS 208: 49 Code of Federal Regulations: 571.208. Washington, DC: US Government Printing Office, 2001.

  7. Hilker, C. E., N. Yoganandan, and F. A. Pintar. Experimental determination of adult and pediatric neck scale factors. Stapp Car Crash J. 46:417–429, 2002.

    PubMed  Google Scholar 

  8. Hubbard, R. P., and D. G. McLeod. Definition and development of a crash dummy head. In: Stapp Car Crash Conference SAE, 1974, pp. 599–628.

  9. Jakobsson, L., H. Norin, and M. Y. Svensson. Parameters influencing AIS 1 neck injury outcome in frontal impacts. Traffic Inj. Prev. 5:156–163, 2004.

    Article  PubMed  Google Scholar 

  10. Kleinberger, M., E. Sun, R. Eppinger, S. Kuppa, and R. Saul. Development of Improved Injury Criteria for the Assessment of Advanced Automotive Restraint Systems. Washington, DC: NHTSA, p. 115, 1998.

    Google Scholar 

  11. Kristjansson, E., G. Leivseth, P. Brinckmann, and W. Frobin. Increased sagittal plane segmental motion in the lower cervical spine in women with chronic whiplash-associated disorders, grades I-II: a case-control study using a new measurement protocol. Spine (Phila Pa 1976) 28:2215–2221, 2003.

    Article  Google Scholar 

  12. Kuppa, S., R. H. Eppinger, F. McKoy, T. Nguyen, F. A. Pintar, and N. Yoganandan. Development of side impact thoracic injury criteria and their application to the modified ES-2 dummy with rib extensions (ES-2re). Stapp Car Crash J. 47:189–210, 2003.

    PubMed  Google Scholar 

  13. Moorhouse, K., B. Donnelly, Y. S. Kang, J. H. Bolte, and R. Herriott. Evaluation of the internal and external biofidelity of current rear impact ATDs to response targets developed from moderate-speed rear impacts of PMHS. Stapp Car Crash J. 56:171–229, 2012.

    PubMed  Google Scholar 

  14. Muser, M. H., F. Walz, and K. U. Schmitt. Injury criteria applied to seat comparison tests. Traffic Inj. Prev. 3:224–232, 2002.

    Article  Google Scholar 

  15. NATO. Test methodology for protection of vehicle occupants against anti-vehicular landmine effects, RTO-TR-HFM-090, edited by 25 FRoH-TG. Research and Technology Organisation (NATO), Neuilly-sur-Seine Cedex, 2007.

  16. Nightingale, R. W., B. S. Myers, and N. Yoganandan. Neck injury biomechanics. In: Accidental Injury: Biomechanics and Prevention, edited by N. Yoganandan, A. M. Nahum, and J. W. Melvin. New York: Springer, 2015, pp. 259–308.

    Google Scholar 

  17. Petitjean, A., X. Torsseille, N. Yoganandan, and F. A. Pintar. Normalization and scaling for human response corridors and development of risk curves. In: Accidental Injury: Biomechanics and Prevention, edited by N. Yoganandan, A. M. Nahum, and J. W. Melvin. New York: Springer, 2015, pp. 769–792.

    Google Scholar 

  18. Philippens, M., J. Wismans, J. Cappon, N. Yoganandan, and F. Pintar. Whole body kinematics using post mortem human subjects in experimental rear impact. In: IRCOBI, Montpelier, 2000, pp. 363–378.

  19. Prasad, P., and R. P. Daniel. A biomechanical analysis of head, neck, and torso injuries to child surrogates due to sudden torso acceleration. In: 28th Stapp Car Crash Conference. Chicago, IL: Society of Automotive Engineering, Inc, 1984, pp. 25–40.

  20. Richter, M., D. Otte, T. Pohlemann, C. Krettek, and M. Blauth. Whiplash-type neck distortion in restrained car drivers: frequency, causes and long-term results. Eur. Spine J. 9:109–117, 2000.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  21. Schmitt, K. U., M. H. Muser, F. H. Walz, and P. F. Niederer. Nkm - A proposal for a neck protection criterion for low-speed rear-end impacts. Traffic Inj. Prev. 3:117–126, 2002.

    Article  Google Scholar 

  22. Somers, J. T., N. Newby, C. Lawrence, R. DeWeese, D. Moorcroft, and S. Phelps. Investigation of the THOR anthropomorphic test device for predicting occupant injuries during spacecraft launch aborts and landing. Front Bioeng. Biotechnol. 2:4, 2014.

    Article  PubMed  PubMed Central  Google Scholar 

  23. Spitzer, W., M. Skovron, L. Salmi, J. Cassiy, J. Duranceau, S. Suissa, and E. Zeiss. Scientific monograph of the Quebec task force on whiplash-associated disorders: redefining “whiplash” and its management. Spine (Phila Pa 1976) 20:3S–73S, 1995.

    Article  Google Scholar 

  24. Stemper, B. D., S. V. Marawar, N. Yoganandan, B. S. Shender, and R. D. Rao. Quantitative anatomy of subaxial cervical lateral mass: an analysis of safe screw lengths for Roy-Camille and magerl techniques. Spine (Phila Pa 1976) 33:893–897, 2008.

    Article  Google Scholar 

  25. Stemper, B. D., N. Yoganandan, and F. A. Pintar. Gender- and region-dependent local facet joint kinematics in rear impact: implications in whiplash injury. Spine (Phila Pa 1976) 29:1764–1771, 2004.

    Article  Google Scholar 

  26. Stemper, B. D., N. Yoganandan, and F. A. Pintar. Validation of a head-neck computer model for whiplash simulation. Med. Biol. Eng. Comput. 42:333–338, 2004.

    Article  CAS  PubMed  Google Scholar 

  27. Stemper, B. D., N. Yoganandan, F. A. Pintar, D. J. Maiman, M. A. Meyer, J. DeRosia, B. S. Shender, and G. Paskoff. Anatomical gender differences in cervical vertebrae of size-matched volunteers. Spine (Phila Pa 1976) 33:E44–E49, 2008.

    Article  Google Scholar 

  28. Sterling, M. A proposed new classification system for whiplash associated disorders—implications for assessment and management. Man Ther. 9:60–70, 2004.

    Article  PubMed  Google Scholar 

  29. Vasavada, A. N., S. Li, and S. L. Delp. Three-dimensional isometric strength of neck muscles in humans. Spine (Phila Pa 1976) 26:1904–1909, 2001.

    Article  CAS  Google Scholar 

  30. Wang, M. C., F. Pintar, N. Yoganandan, and D. J. Maiman. The continued burden of spine fractures after motor vehicle crashes. J. Neurosurg. Spine 10:86–92, 2009.

    PubMed  Google Scholar 

  31. Watanabe, Y., H. Ichikawa, O. Kayama, K. Ono, K. Kaneoka, and S. Inami. Influence of seat characteristics on occupant motion in low-speed rear impacts. Accid. Anal. Prev. 32:243–250, 2000.

    Article  CAS  PubMed  Google Scholar 

  32. Yoganandan, N., M. W. Arun, and F. A. Pintar. Normalizing and scaling of data to derive human response corridors from impact tests. J. Biomech. 47:1749–1756, 2014.

    Article  PubMed  Google Scholar 

  33. Yoganandan, N., M. W. Arun, F. A. Pintar, and A. Banerjee. Lower leg injury reference values and risk curves from survival analysis for male and female dummies: meta-analysis of postmortem human subject tests. Traffic Inj. Prev. 16(Suppl 1):S100–S107, 2015.

    Article  PubMed  Google Scholar 

  34. Yoganandan, N., M. W. Arun, F. A. Pintar, and A. Szabo. Optimized lower leg injury probability curves from postmortem human subject tests under axial impacts. Traffic Inj. Prev. 15(Suppl 1):S151–S156, 2014.

    Article  PubMed  PubMed Central  Google Scholar 

  35. Yoganandan, N., A. Banerjee, F. C. Hsu, C. R. Bass, L. Voo, F. A. Pintar, and F. S. Gayzik. Deriving injury risk curves using survival analysis from biomechanical experiments. J. Biomech. 49:3260–3267, 2016.

    Article  PubMed  Google Scholar 

  36. Yoganandan, N., J. F. Cusick, F. A. Pintar, and R. D. Rao. Whiplash injury determination with conventional spine imaging and cryomicrotomy. Spine (Phila Pa 1976) 26:2443–2448, 2001.

    Article  CAS  Google Scholar 

  37. Yoganandan, N., M. Haffner, D. J. Maiman, H. Nicholds, F. Pintar, J. Jensezn, S. J. Larson, A. Sances, Jr., N. Yoganandan, M. Haffner, D. Maiman, H. Nichols, et al. Epidemiology and injury biomechanics of motor vehicle related trauma to the human spine. In: SAE Technical Paper 892438, doi:10.4271/892438, 1989.

  38. Yoganandan, N., A. M. Nahum, and J. W. Melvin. Accidental Injury: Biomechanics and Prevention. New York, NY: Springer, p. 851, 2015.

    Google Scholar 

  39. Yoganandan, N., and F. A. Pintar. Frontiers in Whiplash Trauma: Clinical and Biomechanical. Burke: IOS Press, p. 590, 1998.

    Google Scholar 

  40. Yoganandan, N., F. Pintar, A. Banerjee, M. Schlick, S. Chirvi, H. Uppal, A. Merkle, L. Voo, and M. Kleinberg. Hybrid III lower leg injury assessment reference curves under axial impacts using matched-pair tests. Biomed. Sci. Instrum. 51:230–237, 2015.

  41. Yoganandan, N., F. A. Pintar, M. Boynton, P. Begeman, P. Prasad, S. M. Kuppa, R. M. Morgan, and R. H. Eppinger. Dynamic axial tolerance of the human foot-ankle complex. In: Stapp Car Crash Conference, Albuquerque, NM, 1996.

  42. Yoganandan, N., F. Pintar, J. Cusick, and M. Kleinberger. Head-neck biomechanics in simulated rear impact. In: 42nd Annual AAAM Conference. Charlottesville, VA, 1998, pp. 209–231.

  43. Yoganandan, N., F. A. Pintar, and M. Kleinberger. Whiplash injury. Biomechanical experimentation. Spine (Phila Pa 1976) 24:83–85, 1999.

    Article  CAS  Google Scholar 

  44. Yoganandan, N., F. A. Pintar, and M. Klienberger. Cervical spine vertebral and facet joint kinematics under whiplash. J. Biomech. Eng. 120:305–307, 1998.

    Article  CAS  PubMed  Google Scholar 

  45. Yoganandan, N., F. A. Pintar, D. J. Maiman, J. F. Cusick, A. Sances, Jr., and P. R. Walsh. Human head-neck biomechanics under axial tension. Med. Eng. Phys. 18:289–294, 1996.

    Article  CAS  PubMed  Google Scholar 

  46. Yoganandan, N., F. A. Pintar, J. Moore, and D. J. Maiman. Sensitivity of THOR and Hybrid III dummy lower neck loads to belt systems in frontal impact. Traffic Inj. Prev. 12:88–95, 2011.

    Article  PubMed  Google Scholar 

  47. Yoganandan, N., F. A. Pintar, B. D. Stemper, J. L. Baisden, R. Aktay, B. S. Shender, and G. Paskoff. Bone mineral density of human female cervical and lumbar spines from quantitative computed tomography. Spine (Phila Pa 1976) 31:73–76, 2006.

    Article  Google Scholar 

  48. Yoganandan, N., F. A. Pintar, B. D. Stemper, J. L. Baisden, R. Aktay, B. S. Shender, G. Paskoff, and P. Laud. Trabecular bone density of male human cervical and lumbar vertebrae. Bone 39:336–344, 2006.

    Article  PubMed  Google Scholar 

  49. Yoganandan, N., F. Pintar, B. D. Stemper, M. S. Schlick, M. Philippens, and J. Wismans. Biomechanics of human occupants in simulated rear crashes: documentation of neck injuries and comparison of injury criteria. Stapp Car Crash J. 44:189–204, 2000.

    CAS  PubMed  Google Scholar 

  50. Yoganandan, N., F. A. Pintar, J. Zhang, and J. L. Baisden. Physical properties of the human head: mass, center of gravity and moment of inertia. J. Biomech. 42:1177–1192, 2009.

    Article  PubMed  Google Scholar 

  51. Yoganandan, N., A. Sances, Jr., D. J. Maiman, J. B. Myklebust, P. Pech, and S. J. Larson. Experimental spinal injuries with vertical impact. Spine (Phila Pa 1976) 11:855–860, 1986.

    Article  CAS  Google Scholar 

  52. Yoganandan, N., B. D. Stemper, F. A. Pintar, D. J. Maiman, B. J. McEntire, and V. C. Chancey. Cervical spine injury biomechanics: applications for under body blast loadings in military environments. Clin Biomech (Bristol, Avon) 28:602–609, 2013.

    Article  Google Scholar 

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Acknowledgments

This material is the result of work supported with resources and use of facilities at the Zablocki VA Medical Center (ZVAMC), Milwaukee, Wisconsin; the Department of Neurosurgery at the Medical College of Wisconsin (MCW), W81XWH-16-1-0010; and the NASA Human Research Program through the HHPC Contract (NNJ15HK11B). The authors NY and FAP are part time employees of the ZVAMC. Views expressed in this article are those of the authors and do not necessarily represent the funding organizations.

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Authors and Affiliations

  1. Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, WI, 53226, USA

    Narayan Yoganandan & Frank A. Pintar

  2. Orthopaedic Surgery, Medical College of Wisconsin, Milwaukee, WI, USA

    Narayan Yoganandan

  3. Division of Biostatistics, Medical College of Wisconsin, Milwaukee, WI, USA

    Anjishnu Banerjee

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  1. Narayan Yoganandan
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  2. Frank A. Pintar
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  3. Anjishnu Banerjee
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Correspondence to Narayan Yoganandan.

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Associate Editor Stefan M. Duma oversaw the review of this article.

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Yoganandan, N., Pintar, F.A. & Banerjee, A. Load-Based Lower Neck Injury Criteria for Females from Rear Impact from Cadaver Experiments. Ann Biomed Eng 45, 1194–1203 (2017). https://doi.org/10.1007/s10439-016-1773-5

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