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Lyme neuroborreliosis: warning about the risk of false negative of CSF Borrelia burgdorferi antibody index related to high level of CSF albumin

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References

  1. Berglund J, Eitrem R, Ornstein K, Lindberg A, Ringér A, Elmrud H et al (1995) An epidemiologic study of Lyme disease in southern Sweden. N Engl J Med 333(20):1319–27

    Article  CAS  Google Scholar 

  2. Huppertz HI, Böhme M, Standaert SM, Karch H, Plotkin SA (1999) Incidence of Lyme borreliosis in the Würzburg region of Germany. Eur J Clin Microbiol Infect Dis Off Publ Eur Soc Clin Microbiol 18(10):697–703

    Article  CAS  Google Scholar 

  3. Mygland A, Ljøstad U, Fingerle V, Rupprecht T, Schmutzhard E, Steiner I (2010) EFNS guidelines on the diagnosis and management of European Lyme neuroborreliosis. Eur J Neurol 17(1):8–16. (e1-4)

    Article  CAS  Google Scholar 

  4. Knudtzen FC, Andersen NS, Jensen TG, Skarphédinsson S (2017) Characteristics and clinical outcome of Lyme neuroborreliosis in a high endemic area, 1995–2014: a retrospective cohort study in Denmark. Clin Infect Dis Off Publ Infect Dis Soc Am 65(9):1489–1495

    Article  CAS  Google Scholar 

  5. Stanek G, Fingerle V, Hunfeld KP, Jaulhac B, Kaiser R, Krause A et al (2011) Lyme borreliosis: clinical case definitions for diagnosis and management in Europe. Clin Microbiol Infect 17(1):69–79

    Article  CAS  Google Scholar 

  6. Reiber H, Peter JB (2001) Cerebrospinal fluid analysis: disease-related data patterns and evaluation programs. J Neurol Sci 184(2):101–122

    Article  CAS  Google Scholar 

  7. Tumani H, Nölker G, Reiber H (1995) Relevance of cerebrospinal fluid variables for early diagnosis of neuroborreliosis. Neurology 45(9):1663–1670

    Article  CAS  Google Scholar 

  8. Djukic M, Schmidt-Samoa C, Lange P, Spreer A, Neubieser K, Eiffert H et al (2012) Cerebrospinal fluid findings in adults with acute Lyme neuroborreliosis. J Neurol 259(4):630–636

    Article  CAS  Google Scholar 

  9. Rupprecht TA, Manz KM, Fingerle V, Lechner C, Klein M, Pfirrmann M et al (2018) Diagnostic value of cerebrospinal fluid CXCL13 for acute Lyme neuroborreliosis. a systemic review and meta-analysis. Clin Microbiol Infect 0(0):1–7

    CAS  Google Scholar 

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Authors and Affiliations

  1. Infectious Disease Department, Nord Franche-Comté Hospital, Trevenans, France

    Timothée Klopfenstein, Vincent Gendrin & Souheil Zayet

  2. Bacteriology Department, University Hospital, Besançon, France

    Damien Fournier

  3. Bacteriology Department, Nord Franche-Comté Hospital, Trevenans, France

    Pauline Garnier

  4. Lyme Borreliosis French National Reference Center, University Hospital, Strasbourg, France

    Antoine Grillon

Authors
  1. Timothée Klopfenstein
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  2. Damien Fournier
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  3. Vincent Gendrin
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  4. Pauline Garnier
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  5. Antoine Grillon
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  6. Souheil Zayet
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Correspondence to Timothée Klopfenstein.

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Klopfenstein, T., Fournier, D., Gendrin, V. et al. Lyme neuroborreliosis: warning about the risk of false negative of CSF Borrelia burgdorferi antibody index related to high level of CSF albumin. Eur J Clin Microbiol Infect Dis 41, 1151–1153 (2022). https://doi.org/10.1007/s10096-022-04471-y

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  • DOI: https://doi.org/10.1007/s10096-022-04471-y

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