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Manufacture and characterization of optimized red ginseng drinks containing herbal medicine extracts

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Abstract

The optimum mixing ratio of red ginseng, herbal medicine extracts, and oligosaccharides for diabetic improvement was investigated and verified through animal experiments. Using the optimum mixing technique, 2% red ginseng extract, 15% oligosaccharides, and 83% herbal medicine extracts were determined to be optimal for red ginseng beverages. The taste was improved as the amount of red ginseng decreased and oligosaccharides increased, whereas antioxidative activity was increased with increased red ginseng. In the animal model in which streptozotocin was administered to BALB-c mice, the red ginseng administration group exhibited lower blood glucose than the diabetic control group, and the blood glucose level was lower in the herbal medicine and red ginseng extract administration group. Insulin concentration was slightly increased by the red ginseng beverage, and hepatotoxicity due to excessive intake of red ginseng beverages was not detected.

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References

  • Attele AS, Wu JA, Yuan CS. Ginseng pharmacology: multiple constituents and multiple actions. Biochem. Pharmacol. 58: 1685–1693 (1999)

    Article  CAS  Google Scholar 

  • Ban YJ, Yang BW, Baik MY, Hahm YT, Kim BY. Optimization of the manufacturing process for black ginseng. J. Korean Soc. Appl. Biol. Chem. 53: 71–77 (2010)

    Article  CAS  Google Scholar 

  • Blois MS. Antioxidant determinations by the use of a stable free radical. Nature. 181: 1199–1200 (1958)

    Article  CAS  Google Scholar 

  • Cornell JA. Experiment with Mixture: Design, Models, and the Analysis of Mixture Data. Wiley, New York. pp. 1–8 (1990)

    Google Scholar 

  • Hwang HA, Lee NK, Cho IJ, Hahn YT, Kown KO, Kim BY. Selection of microorganisms and optimization of manufacture process for Cheonggukjang. Korean J. Food Sci. Technol. 40: 406–411 (2008)

    Google Scholar 

  • Keum YS, Park KK, Lee JM, Chun KS, Park JH, Lee SK, Kwon H, Surh YJ. Antioxidant and anti-tumor promoting activities of the methanol extract of heat-processed ginseng. Cancer Lett. 150: 41–48 (2000)

    Article  CAS  Google Scholar 

  • Kim EM. Formulation and quality characteristics of noni beverage mixed with red ginseng, Rebus coreanus and pomegranate extracts. Korean J. Culinary Research. 17: 259–269 (2011)

    Google Scholar 

  • Kim HO, Park MJ, Han JS. Effects of fermented red ginseng supplementation on blood glucose and insulin resistance in type 2 diabetic patients. J. Korean Soc. Food Sci. Nutr. 40: 696–703 (2011a)

    Article  CAS  Google Scholar 

  • Kim JP, Kim JH, Gang GL, Yang YS, Hong SJ, Kim ES, Moon YW, Lee JC, Song HJ, Chung JK. A survey on the content and safety of red ginseng products. Korean J. Food Sci Technol. 43: 413–418 (2011b)

    Article  Google Scholar 

  • Kim MH, Lee YC, Choi SY, Cho CW, Rho JH. Characteristics of acid pre-treated red ginseng and its decoction. J. Ginseng Res. 33: 343–348 (2009)

    Article  Google Scholar 

  • Kim SH, Kang JS, Lee SJ, Chung YJ. Antidiabetic effect of Korean red ginseng by puffing process in streptozotocin-induced diabetic rats. J. Korean Soc. Food Sci. Nutr. 37: 701–707 (2008)

    Article  CAS  Google Scholar 

  • Koak JH, Kang BS, Hahm YT, Park CS, Baik MY, Kim BY. Blending of different domestic grape wines using mixture design and optimization technique. Food Sci. Biotech. 19: 1011–1018 (2010)

    Article  Google Scholar 

  • Lee HA, Sim HS, Choi KJ, Lee HB. Hypoglycemic action of red ginseng components (II): Investigation of the effect of fat soluble fraction from red ginseng on enzymes related to glucose metabolism in cultured rat hepatocytes. J. Ginseng Research. 22: 51–59 (1998)

    CAS  Google Scholar 

  • Lee KJ. Characteristics of physico-chemical properties and analysis of functional components in soymilk with red ginseng extract. Chosun University, School of Food Drug. MS Thesis. (2012)

  • Lee SK, So SH, Hwang EI, Koo BS, Han GH, Ko SB, Kim NM. Effect of ginseng and herbal plant mixtures on anti-obesity in obese SD rat induced by high fat diet. J. Korean Soc. Food Sci. Nutr. 37: 437–444 (2008)

    Article  Google Scholar 

  • Lee YR, Yoon N. Anti-oxidative and anti-diabetic effects of methanol extracts from medicinal plants. J. Korean Soc. Food Sci. Nutr. 44: 681–686 (2015)

    Article  CAS  Google Scholar 

  • Moon CY, Yoon WB, Hahm YT, Kim HK, Baik MY, Kim BY. Optimization of processing conditions and evaluation of shelf-life for Jeonbokjang products. Food Sci. Biotech. 20: 1419–1424 (2011)

    Article  CAS  Google Scholar 

  • Park HJ, Jung DH, Joo HM, Kang NS, Jang SA, Lee JG, Sohn EH. The comparative study of anti-allergic and anti-inflammatory effects by fermented red ginseng and red ginseng. Korean J. Plant Resour. 23: 415–422 (2010)

    Google Scholar 

  • Statistics Korea. 2008. The Cause of Death Statistics. Annual Report on the Cause of Death Statistics. p. 20, Statistics Korea, Korea (2008)

  • Yang JW, Sung HS, Park MH, Kim WJ, Hong SK. Studies on the manufacturing of soft ginseng drink Part I Purification procedure of raw ginseng extracts. Korean J. Ginseng Sci. 4: 72–87 (1980)

    Google Scholar 

  • Yang KM. The effects of Chungkukjang powder supplements on the regulation of blood glucose and inflammation in diabetic rats. Korean J. Food Cookery Sci. 31: 118–127 (2015)

    Article  CAS  Google Scholar 

Download references

Acknowledgements

The research was supported by the Ministry of SMEs and Startups in 2010.

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Correspondence to Byung-Yong Kim.

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Kim, HJ., Baik, MY., Yang, BW. et al. Manufacture and characterization of optimized red ginseng drinks containing herbal medicine extracts. Food Sci Biotechnol 28, 1433–1438 (2019). https://doi.org/10.1007/s10068-019-00593-w

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  • DOI: https://doi.org/10.1007/s10068-019-00593-w

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