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The effect of radiotherapy delivery time and obturation materials on the fracture resistance of mandibular premolars

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Abstract

Objectives

This ex vivo study was performed to investigate the effect of radiotherapy (RT) delivery time on fracture resistance of mandibular premolars filled with Biodentine or gutta-percha/sealer (GPS).

Materials and methods

Seventy-two mandibular premolars were used in this study. Randomly selected 24 teeth were kept intact for the control groups (with and without irradiation). Then, the remaining 48 teeth were randomly assigned into 4 groups (n = 12) according to RT delivery time (irradiated before or after root canal treatment) and obturation materials as follows: Group RT + GPS, Group: GPS + RT, Group RT + Biodentine and Group Biodentine + RT. The samples were either initially endodontically treated and then irradiated or initially irradiated and then endodontically treated with one of the abovementioned materials. The samples were irradiated at 2 Gy per fraction, 5 times a week for a total dose of 60 Gy in 30 fractions over 6 weeks. The roots were embedded in self-polymerizing acrylic resin. The fracture resistance was evaluated in a universal testing machine. Data was analyzed by one-way ANOVA and Games-Howell post hoc test at p < 0.05.

Results

Radiation therapy significantly reduced fracture resistance of intact teeth (p < 0.05). The highest fracture resistance was observed in intact/non-irradiated teeth and the lowest fracture resistance in Biodentine + RT group (p < 0.05). The effect of RT delivery time was insignificant when GPS was preferred as the root canal filling material (p > 0.05); it was significant when preferring Biodentine (p < 0.05). When RT was applied to the teeth after Biodentine obturation, the fracture resistance decreased significantly compared to the teeth that were obturated with GPS after or before RT application (p < 0.05).

Conclusion

Both RT time and obturation materials (Biodentine or gutta-percha/sealer) affect the fracture resistance of the endodontically treated teeth.

Clinical relevance

Endodontic treatment could be completed with both materials after RT; however, when the endodontic treatment was initially completed and the teeth were subsequently exposed to RT, it was shown that the reinforcement effect of Biodentine decreased.

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Authors and Affiliations

  1. Department of Endodontics, Faculty of Dentistry, Zonguldak Bülent Ecevit University, Zonguldak, Turkey

    Sevinç Aktemur Türker & Sena Kaşıkçı

  2. Department of Endodontics, Faculty of Dentistry, Hacettepe University, Ankara, Turkey

    Emel Uzunoğlu Özyürek

  3. Department of Endodontics, Faculty of Dentistry, Istanbul Medipol University, Istanbul, Turkey

    Keziban Olcay

  4. Department of Radiation Oncology, Faculty of Medicine, Zonguldak Bülent Ecevit University , Zonguldak, Turkey

    Özlem Elmas

Authors
  1. Sevinç Aktemur Türker
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  2. Sena Kaşıkçı
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  3. Emel Uzunoğlu Özyürek
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  4. Keziban Olcay
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  5. Özlem Elmas
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Correspondence to Sevinç Aktemur Türker.

Ethics declarations

This in vitro study was approved by the Ethics Committee of Istanbul Medipol University (Registration Number 478).

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The authors declare that they have no conflict of interest.

Ethical approval

This in vitro study was approved by the Ethics Committee of Istanbul Medipol University (Registration Number 478). This article does not contain any studies with human participants or animals performed by any of the authors.

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Aktemur Türker, S., Kaşıkçı, S., Uzunoğlu Özyürek, E. et al. The effect of radiotherapy delivery time and obturation materials on the fracture resistance of mandibular premolars. Clin Oral Invest 25, 901–905 (2021). https://doi.org/10.1007/s00784-020-03378-2

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  • DOI: https://doi.org/10.1007/s00784-020-03378-2

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