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Long-term results of flow diversion in the treatment of intracranial aneurysms: a retrospective data analysis of a single center

  • Original Article - Vascular Neurosurgery - Aneurysm
  • Published:
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Abstract

Purpose

Endovascular techniques are frequently used for the treatment of intracranial aneurysms and flow diverter stents are relatively new and important devices in this field. The aim of our study is to report long-term follow-up results of flow diversion treatment.

Methods

We retrospectively examined angiographic images and clinical reports of 133 patients (female, 112 [84%]; mean age, 46.3 years [range, 12–70 years]) who were treated with flow diverters between 2008 and 2013 and were followed up radiologically at least 1 year. The aneurysms treated with flow diverters were assessed according to technical problems, stent patency, residual filling, re-growth, and occlusion status, and the patients were assessed according to morbidity and mortality.

Results

Except for ten patients, one aneurysm was treated per patient. Median duration of the follow-up was 927 days. Total occlusion rates in angiographic follow-up were found 76.2% for the sixth-month, 86.7% for the first-year, 93.6% for the third-year, 94.2% for the fifth-year, and 90.2% for entire follow-up period. Nine stent morphology changes were observed in the angiographic controls. Overall mortality and morbidity rates were 3.7% and 4.3%, respectively.

Conclusion

Despite technical difficulties and delayed hemorrhages, flow diverter stents are effective tools for the treatment of challenging aneurysms in the long run. Nonetheless, long-term results of flow diversion treatment must be evaluated hemodynamically and clinically in multicenter studies.

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Author information

Authors and Affiliations

  1. Department of Radiology, Canakkale Mehmet Akif Ersoy State Hospital, Canakkale, Turkey

    Bora Korkmazer

  2. Department of Radiology, Istanbul Training and Research Hospital, Istanbul, Turkey

    Burak Kocak

  3. Department of Radiology, Division of Neuroradiology, Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, 34098, Istanbul, Turkey

    Civan Islak, Naci Kocer & Osman Kizilkilic

Authors
  1. Bora Korkmazer
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  2. Burak Kocak
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  3. Civan Islak
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  4. Naci Kocer
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  5. Osman Kizilkilic
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Corresponding author

Correspondence to Osman Kizilkilic.

Ethics declarations

All procedures performed in the studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. Informed consent was obtained from all individual participants included in the study.

Conflict of interest

NK and CI have consultancy and proctoring agreement with Microvention, Inc.

Study-cohort overlap

Some of the patients’ short- and mid-term results were reported in authors’ other previous studies. But the focus of this study is the long-term results.

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This article is part of the Topical Collection on Vascular Neurosurgery - Aneurysm

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Korkmazer, B., Kocak, B., Islak, C. et al. Long-term results of flow diversion in the treatment of intracranial aneurysms: a retrospective data analysis of a single center. Acta Neurochir 161, 1165–1173 (2019). https://doi.org/10.1007/s00701-019-03912-6

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  • DOI: https://doi.org/10.1007/s00701-019-03912-6

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