Abstract
Study design
Narrative review with case illustration.
Objective
Provide an overview of existing management strategies to suggest a guideline for surgical management of lumbar disk herniation in pregnant women based on time of presentation.
Methods
We performed a narrative review on the topic using the PubMed database. A total of 63 relevant articles published after 1992 were identified, of which 17 fulfilled selection criteria.
Results
A total of 22 published cases of spine surgery for disk herniation during pregnancy were found in 17 studies on the topic. Prone positioning was reported in the majority of cases during the first and early second trimester. C-sections were performed prior to spine surgery in the prone position for the majority of patients operated during the third trimester. The left lateral position with continued pregnancy was preferred during the latter half of the second trimester when delivery of the fetus cannot yet be performed but surgery is indicated.
Conclusion
Spine surgery during pregnancy is a rare scenario but can be performed safely when needed if providers adhere to general guidelines. Surgical approaches and overall management are influenced by the stage of pregnancy.
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References
Abou-Shameh MA, Dosani D, Gopal S, McLaren AG (2006) Lumbar discectomy in pregnancy. Int J Gynaecol Obstet 92:167–169
ACOG (2011) ACOG Committee Opinion No. 474: nonobstetric surgery during pregnancy. Obstet Gynecol 117:420–421
Adogwa O, Elsamadicy A, Reiser E, Ziegler C, Freischlag K, Cheng J, Bagley CA (2016) Comparison of surgical outcomes after anterior cervical discectomy and fusion: does the intra-operative use of a microscope improve surgical outcomes. J Spine Surg 2:25–30
Akino K, Akita S, Yakabe A, Mineda T, Hayashi T, Hirano A (2008) Human mesenchymal stem cells may be involved in keloid pathogenesis. Int J Dermatol 47:1112–1117
Al-areibi A, Coveney L, Singh S, Katsiris S (2007) Case report: anesthetic management for sequential cesarean delivery and laminectomy. Can J Anaesth 54:471–474
Antón Capitán B, Malillos Torán M (2015) Síndrome de cauda equina en paciente embarazada con hernia de disco masiva. Revista Española de Cirugía Ortopédica y Traumatología
Barash PG (2009) Clinical Anesthesia. Lippincott Williams & Wilkins
Bigos S, Bowyer O, Braen G, Brown K, Deyo R, Haldeman S, Hart JL, Johnson EW, Keller R, Kido D (1994) Acute lower back problems in adults. Rockville, MD: Agency for Health Care Policy and Research
Brent RL (1999) Utilization of developmental basic science principles in the evaluation of reproductive risks from pre- and postconception environmental radiation exposures. Teratology 59:182–204
Brown MD, Brookfield KF (2004) Lumbar disc excision and cesarean delivery during the same anesthesia. A case report. J Bone Joint Surg Am 86-A:2030–2032
Brown MD, Levi AD (2001) Surgery for lumbar disc herniation during pregnancy. Spine 26:440–443
Bydon M, Macki M, Abt NB, Sciubba DM, Wolinsky JP, Witham TF, Gokaslan ZL, Bydon A (2015) Clinical and surgical outcomes after lumbar laminectomy: An analysis of 500 patients. Surg Neurol Int 6:S190–S193
Chestnut DH (2012) Nonobstetric Surgery During Pregnancy. Yearb Anesthesiol Pain Manag 2012:335–336
Cohen-Kerem R, Railton C, Oren D, Lishner M, Koren G (2005) Pregnancy outcome following non-obstetric surgical intervention. Am J Surg 190:467–473
Coleman MT, Trianfo VA, Rund DA (1997) Nonobstetric emergencies in pregnancy: trauma and surgical conditions. Am J Obstet Gynecol 177:497–502
Crowhurst JA (2002) Anaesthesia for non-obstetric surgery during pregnancy. Acta Anaesthesiol Belg 53:295–297
Dupont J, Pierre A, Froment P, Moreau C (2003) The insulin-like growth factor axis in cell cycle progression. Horm Metab Res 35:740–750
Edwards DRV, Aldridge T, Baird DD, Funk MJ, Savitz DA, Hartmann KE (2012) Periconceptional over-the-counter nonsteroidal anti-inflammatory drug exposure and risk for spontaneous abortion. Obstet Gynecol 120:113–122
Fager CA (1994) Observations on spontaneous recovery from intervertebral disc herniation. Surg Neurol 42:282–286
Fahy UM, Oni M, Findlay D, Sell P (1998) Surgical management of herniated lumbar disc in pregnancy. J Obstet Gynaecol 18:544–545
Flickinger JC (2011) A radiobiological analysis of multicenter data for postoperative keloid radiotherapy. Int J Radiat Oncol Biol Phys 79:1164–1170
Garmel SH, Guzelian GA, D’Alton JG, D’Alton ME (1997) Lumbar disk disease in pregnancy. Obstet Gynecol 89:821–822
Geftler A, Sasson A, Shelef I, Perry ZH, Atar D (2015) Cauda equina syndrome in a 36 week gravida patient. Isr Med Assoc J 17:522–523
Gupta P, Gurumurthy M, Gangineni K, Anarabasu A, Keay SD (2008) Acute presentation of cauda equina syndrome in the third trimester of pregnancy. Eur J Obstet Gynecol Reprod Biol 140:279–281
Hakan T (2012) Lumbar disk herniation presented with cauda equina syndrome in a pregnant woman. J Neurosci Rural Pract 3:197–199
Hall EJ (1991) Scientific view of low-level radiation risks. Radiographics 11:509–518
Hamilton BE MJ, Osterman MJK, et al. (2015) Births: Final data for 2014. National Vital Statistics Reports Vol. 64, No. 12
Hayakawa K, Mizutani J, Suzuki N, Haas C, Kondo A, Otsuka S, Fukuoka M, Otsuka T (2016) Surgical management of the pregnant patient with lumbar disc herniation in the latter stage of the second trimester. Spine
Iyilikçi L, Erbayraktar S, Tural AN, Celik M, Sannav S (2004) Anesthetic management of lumbar discectomy in a pregnant patient. J Anesth 18:45–47
Kathirgamanathan A, Jardine AD, Levy DM, Grevitt MP (2006) Lumbar disc surgery in the third trimester—with the fetus in utero. Int J Obstet Anesth 15:181–182
Katz JD, Hook R, Barash PG (1977) Fetal heart rate monitoring in patients undergoing surgery. Surv Anesthesiol 21:286–287
Kim HS, Kim SW, Lee SM, Ho S (2007) Endoscopic discectomy for the cauda equina syndrome during third trimester of pregnancy. J Korean Neurosurg Soc 42:419
LaBan MM, Perrin JC, Latimer FR (1983) Pregnancy and the herniated lumbar disc. Arch Phys Med Rehabil 64:319–321
LaBan MM, Rapp NS, von Oeyen P, Meerschaert JR (1995) The lumbar herniated disk of pregnancy: a report of six cases identified by magnetic resonance imaging. Arch Phys Med Rehabil 76:476–479
Lee JM, Han IH, Moon SH, Choi BK (2011) Surgery for recurrent lumbar disc herniation during pregnancy: a case report. Korean J Spine 8:304–306
MacLennan AH, Nicolson R, Green RC, Bath M (1986) Serum relaxin and pelvic pain of pregnancy. Lancet 2:243–245
Martel CG, Volpi-Abadie J, Ural K (2015) Anesthetic management of the parturient for lumbar disc surgery in the prone position. Ochsner J 15:259–261
Marulasiddappa V, Raghavendra B, Nethra H (2014) Anaesthetic management of a pregnant patient with intracranial space occupying lesion for craniotomy. Indian J Anaesth 58:739–741
Matthews LJ, McConda DB, Lalli TAJ, Daffner SD (2015) Orthostetrics: management of orthopedic conditions in the pregnant patient. Orthopedics 38:e874–e880
Moon JH, Kwak SS, Park G, Jung HY, Yoon BS, Park J, Ryu KS, Choi SC, Maeng I, Kim B, Jun EK, Kim S, Kim A, Oh S, Kim H, Kim KD, You S (2008) Isolation and characterization of multipotent human keloid-derived mesenchymal-like stem cells. Stem Cells Dev 17:713–724
Nielsen GL (2001) Risk of adverse birth outcome and miscarriage in pregnant users of non-steroidal anti-inflammatory drugs: population based observational study and case–control study. BMJ 322:266–270
Nielsen GL, Skriver MV, Pedersen L, Sørensen HT (2004) Danish group reanalyses miscarriage in NSAID users. BMJ 328:109
Ninke T, Thoma-Jennerwein S, Blunk J, Annecke T (2015) Anesthesia and pain management during pregnancy. Anaesthesist 64:347–356
Ochi H, Ohno R, Kubota M, Hanyu R, Sakai K, Sugawara Y, Mukasa F, Kaneko K (2014) Case report: The operation for the lumbar disk herniation just after cesarean delivery in the third trimester of pregnancy. Int J Surg Case Rep 5:1178–1182
Orvieto R, Achiron A, Ben-Rafael Z, Gelernter I, Achiron R (1994) Low-back pain of pregnancy. Acta Obstet Gynecol Scand 73:209–214
Park SH, Kim MJ, Kwon J, Park JP, Park MS, Lim JS, Kim JH, Kim KW (2007) Solitary fibrous tumor arising from stomach: CT findings. Yonsei Med J 48:1056–1060
Ray JG, Vermeulen MJ, Bharatha A, Montanera WJ, Park AL (2016) Association between MRI exposure during pregnancy and fetal and childhood outcomes. JAMA 316:952–961
Timothy J, Anthony R, Tyagi A, Porter D, van Hille PT (1999) A case of delayed diagnosis of the cauda equina syndrome in pregnancy. Aust N Z J Obstet Gynaecol 39:260–261
Vougioukas VI, Kyroussis G, Gläsker S, Tatagiba M, Scheufler KM (2004) Neurosurgical interventions during pregnancy and the puerperium: clinical considerations and management. Acta Neurochir 146:1287–1291, discussion 1291–1282
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Ardaillon, H., Laviv, Y., Arle, J.E. et al. Lumbar disk herniation during pregnancy: a review on general management and timing of surgery. Acta Neurochir 160, 1361–1370 (2018). https://doi.org/10.1007/s00701-017-3098-z
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DOI: https://doi.org/10.1007/s00701-017-3098-z