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Simultaneous voltammetric sensing of acetaminophen, epinephrine and melatonin using a carbon paste electrode modified with zinc ferrite nanoparticles

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Abstract

A highly selective electrochemical sensor was fabricated based on a modified carbon paste electrode with zinc ferrite nanoparticles (ZnFe2O4 NPs). The nanocomposite has attractive properties such as high surface-to-volume ratio and good electrocatalytic activity towards the drugs acetaminophen (AC), epinephrine (EP), and melatonin (MT), best at working voltages of 0.35, 0.09 and 0.55 V (vs. Ag/AgCl), respectively. The linear ranges (and detection limits) are 6.5–135 (0.4) μmol L−1 for AC, 5–100 (0.7) μmol L−1 for EP, and 6.5–145 (3) μmol L−1 for MT.

A novel electrochemical sensor based on a modified carbon paste electrode with zinc ferrite nanoparticles (ZnFe2O4) for the simultaneous detection of the acetaminophen, epinephrine and melatonin was fabricated

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Acknowledgements

The authors would like to acknowledge the financial support of the Isfahan Payame Noor University.

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Authors and Affiliations

  1. Chemistry Department, Payame Noor University, Tehran, 19395-4697, Islamic Republic of Iran

    Nahid Tavakkoli, Nasrin Soltani, Mahbobeh Ramezani & Hossein Salavati

  2. Faculty of Medicine, Ilam University of Medical Sciences, Ilam, 69391-77143, Islamic Republic of Iran

    Faezeh Shahdost-fard

  3. Physics Department, Payame Noor University, Tehran, 19395-4697, Islamic Republic of Iran

    Mohammad Reza Jalali

Authors
  1. Nahid Tavakkoli
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  2. Nasrin Soltani
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  3. Faezeh Shahdost-fard
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  4. Mahbobeh Ramezani
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  5. Hossein Salavati
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  6. Mohammad Reza Jalali
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Correspondence to Nahid Tavakkoli.

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Highlights

• For the first time simultaneous measurement of acetaminophen, epinephrine, and melatonin was successfully achieved.

• A sensor was fabricated by a modified carbon past electrode with zinc ferrite nanoparticles as an efficient nanocomposite.

• The prepared nanocomposite has some properties such as high surface to volume ratio and good electrocatalytic effect.

• Minimum substrates and materials were handled for a possible point of care assays.

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Tavakkoli, N., Soltani, N., Shahdost-fard, F. et al. Simultaneous voltammetric sensing of acetaminophen, epinephrine and melatonin using a carbon paste electrode modified with zinc ferrite nanoparticles. Microchim Acta 185, 479 (2018). https://doi.org/10.1007/s00604-018-3009-x

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  • DOI: https://doi.org/10.1007/s00604-018-3009-x

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