Abstract
We report a rare case of diffusely infiltrative squamous cell carcinoma of the esophagus. The patient, a 68-year-old man, was admitted to our hospital for investigation of dysphagia. Esophagography and upper gastrointestinal endoscopy revealed esophageal stenosis and gastric cancer. As a biopsy from the esophagus revealed no sign of malignancy, he underwent only distal gastrectomy. After 3 months, the stenosis became worse. Again, biopsy from a gastrointestinal endoscopy showed no malignancy, but endobronchial ultrasound-guided transbronchial needle aspiration revealed squamous cell carcinoma of the esophagus. Despite various treatments, the patient died of disease progression 20 months after its onset. Autopsy revealed diffusely infiltrative squamous cell carcinoma of the esophagus, which is a rare malignancy with few case reports documented.
This is a preview of subscription content, log in via an institution to check access.
References
Japanese Society for Esophageal Diseases. Guide lines for the clinical and pathologic studies for carcinoma of the esophagus. Jpn J Surg. 1976;6:79–86.
Natsugoe S, Matsushita Y, Kijima F, Tokuda K, Shimada M, Shirao K, et al. Diffusely infiltrative squamous cell carcinoma of the esophagus. Surg Today. 1998;28:129–34.
Kawaguchi H, Kuwano H, Araki K, Egashira A, Saeki H, Ohga T, et al. Esophageal carcinoma showing a long stricture due to prominent lymphatic permeation: report of a case. Surg Today. 1999;29:545–8.
Yasufuku K, Chiyo M, Sekine Y, Chhajed PN, Shibuya K, Iizasa T, et al. Real-time endobronchial ultrasound-guided transbronchial needle aspiration of mediastinal and hilar lymph nodes. Chest. 2004;126:122–8.
John V, Stirling AJ, Mathews HR. Rheumatoid stricture of oesophagus. Br Med J. 1978;1:479.
Picciocchi A, Cardillo G, D’Ugo D, Castrucci G, Mascellari L, Granone P. Surgical treatment of achalasia: a retrospective comparative study. Surg Today. 1993;23:855–9.
Fujita H, Sueyoshi S, Tanaka T, Tanaka Y, Sasahara H, Shirouzu K, et al. Prospective non-randomized trial comparing esophagectomy-followed-by-chemoradiotherapy versus chemoradiotherapy-followed-by-esophagectomy for T4 esophageal cancers. J Surg Oncol. 2005;90:209–19.
Yasumura T, Maruyama T, Kaji S, Yagawa A, Ozawa T. Complete response in a case of advanced esophageal and gastric double cancer treated by chemotherapy of TS-1 and low-dose cisplatin (in Japanese with English abstract). Gan To Kagaku Ryoho. 2006;33:2069–71.
Iwase H, Indo T, Shimada M, Tsuzuki T, Nakarai K, Kaida S, et al. Esophageal cancer with colonic metastasis successfully treated by chemoradiotherapy followed by chemotherapy with S-1 and cisplatin. Int J Clin Oncol. 2004;9:398–402.
Conflict of interest
A. Usui and his co-authors have no conflict of interest.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Usui, A., Akutsu, Y., Kano, M. et al. Diffusely infiltrative squamous cell carcinoma of the esophagus presenting diagnostic difficulty: report of a case. Surg Today 43, 794–799 (2013). https://doi.org/10.1007/s00595-012-0400-9
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00595-012-0400-9