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Association of frailty with healthcare resource utilization after open thoracic/thoracolumbar posterior spinal fusion for adult spinal deformity

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Abstract

Purpose

The Hospital Frailty Risk Score (HFRS) is a frailty-identifying metric developed using ICD-10-CM codes. While other studies have examined frailty in adult spinal deformity (ASD), the HFRS has not been assessed in this population. The aim of this study was to utilize the HFRS to investigate the impact of frailty on outcomes in ASD patients undergoing posterior spinal fusion (PSF).

Methods

A retrospective study was performed using the 2016–2019 National Inpatient Sample database. Adults with ASD undergoing elective PSF were identified using ICD-10-CM codes. Patients were categorized into HFRS-based frailty cohorts: Low (HFRS < 5) and Intermediate-High (HFRS ≥ 5). Patient demographics, comorbidities, intraoperative variables, and outcomes were assessed. Multivariate regression analyses were used to determine whether HFRS independently predicted extended length of stay (LOS), non-routine discharge, and increased cost.

Results

Of the 7500 patients identified, 4000 (53.3%) were in the Low HFRS cohort and 3500 (46.7%) were in the Intermediate-High HFRS cohort. On average, age increased progressively with increasing HFRS scores (p < 0.001). The frail cohort experienced more postoperative adverse events (p < 0.001), greater LOS (p < 0.001), accrued greater admission costs (p < 0.001), and had a higher rate of non-routine discharge (p < 0.001). On multivariate analysis, Intermediate-High HFRS was independently associated with extended LOS (OR: 2.58, p < 0.001) and non-routine discharge (OR: 1.63, p < 0.001), though not increased admission cost (OR: 1.01, p = 0.929).

Conclusion

Our study identified HFRS to be significantly associated with prolonged hospitalizations and non-routine discharge. Other factors that were found to be associated with increased healthcare resource utilization include age, Hispanic race, West hospital region, large hospital size, and increasing number of AEs.

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Authors and Affiliations

  1. Department of Neurosurgery, Yale University School of Medicine, 333 Cedar Street, New Haven, CT, 06510, USA

    Aladine A. Elsamadicy, Andrew B. Koo, Josiah J. Z. Sherman, Margot Sarkozy, Benjamin C. Reeves, Samuel Craft, Sumaiya Sayeed, Mani Ratnesh S. Sandhu & Ehud Mendel

  2. Department of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, MD, USA

    Andrew M. Hersh & Daniel M. Sciubba

  3. Department of Neurosurgery, Zucker School of Medicine at Hofstra, Long Island Jewish Medical Center and North Shore University Hospital, Northwell Health, Manhasset, NY, USA

    Sheng-Fu Larry Lo & Daniel M. Sciubba

  4. Department of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA

    John H. Shin

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  1. Aladine A. Elsamadicy
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Contributions

AAE involved in conceptualization, methodology, data curation, formal analysis, investigation, writing review and editing, and project administration. ABK involved in methodology, data curation, formal analysis, and writing review and editing. JJZS involved in investigation, writing original, and writing review and editing. MS involved in data curation and formal analysis. BCR involved in investigation and writing review and editing. SC involved in investigation and writing review and editing. SS involved in investigation and writing review and editing. MRSS involved in investigation and writing review and editing. AMH involved in writing review and editing. S-FLL involved in supervision, resources, writing review and editing, and project administration. JHS involved in supervision, resources, writing review and editing, and project administration. EM involved in supervision, resources, writing review and editing, and project administration. DMS involved in supervision, resources, writing review and editing, and project administration.

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Correspondence to Aladine A. Elsamadicy.

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Appendix

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Table 9 Inclusion criteria
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9,

Table 10 Supplementary comorbidity diagnostic codes utilized
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10,

Table 11 Supplementary complication diagnostic does utilized
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11.

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Elsamadicy, A.A., Koo, A.B., Sherman, J.J.Z. et al. Association of frailty with healthcare resource utilization after open thoracic/thoracolumbar posterior spinal fusion for adult spinal deformity. Eur Spine J (2023). https://doi.org/10.1007/s00586-023-07635-2

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