Skip to main content

Advertisement

SpringerLink
Log in

Characteristic differences between vestibular migraine and migraine only patients

  • Original Communication
  • Published:
Journal of Neurology Aims and scope Submit manuscript

Abstract

Background

Vestibular migraine (VM) is one of the most common causes of vertigo in clinical practice but it is not always easy to make the correct diagnosis. Our aims were to find out how VM patients differ from migraine only (MO) patients, to evaluate co-morbid depression in these two groups and to determine if their disease has an effect on their quality of life.

Methods

We studied 50 definite VM and 35 MO patients. Each patient was asked about: age of onset, duration of headaches, presence of aura, headache characteristics, triggering factors, associated features, motion sickness history and family history of migraine. VM patients were also asked about their vertigo attacks and accompanying symptoms. Each patient also completed the following questionnaires: (1) Migraine Disability Assessment Scale (MIDAS); (2) headache severity with VAS (Visual Analog Scale); (3) Allodynia Symptom Checklist (ASC-12); (4) Beck Depression Inventory (BDI); (5) World Health Organization Quality of Life Questionnaire Short Form-12 (WHOQL-SF12); (6) Activities Specific Balance Confidence Scale (ABC). VM patients also completed the Dizziness Handicap Inventory (DHI).

Results

We found that VM patients were more likely than MO patients to be female, post-menopausal, depressed, motion sick, complaining of imbalance and of food-triggered headaches. In contrast, MO patients were more likely than VM patients to have severe headaches and that these can be triggered by certain odors and by noise.

Conclusion

Our findings showed differences between VM and MO patients and attention to these differences could help clinicians diagnose, characterize and manage their VM patients.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

Similar content being viewed by others

References

  1. Boenheim F (1917) Uber familiare hemicrania vestibularis. Neurol Zentralbl 36:226–229

    Google Scholar 

  2. Lempert T, Neuhauser H (2009) Epidemiology of vertigo, migraine and vestibular migraine. J Neurol 256(3):333–338. https://doi.org/10.1007/s00415-009-0149-2

    Article  PubMed  Google Scholar 

  3. Headache Classification Committee of the International Headache Society (IHS) (2013) The international classification of headache disorders, 3rd edition (beta version). Cephalalgia 33(9):629–808. https://doi.org/10.1177/0333102413485658

    Article  Google Scholar 

  4. Dieterich M, Obermann M, Celebisoy N (2016) Vestibular migraine: the most frequent entity of episodic vertigo. J Neurol 263(Suppl 1):S82–S89. https://doi.org/10.1007/s00415-015-7905-2

    Article  CAS  PubMed  Google Scholar 

  5. Welgampola MS, Young AS, Pogson JM et al (2019) Dizziness demystified. Pract Neurol 19(6):492–501. https://doi.org/10.1136/practneurol-2019-002199

    Article  PubMed  Google Scholar 

  6. Ertaş M, Siva A, Dalkara T et al (2004) Validity and reliability of the turkish migraine disability assessment (MIDAS) questionnaire headache. J Head Face Pain 44(8):786–793. https://doi.org/10.1111/j.1526-4610.2004.04146.x

    Article  Google Scholar 

  7. Ekizoglu E, Baykan B, Orhan EK et al (2012) The analysis of allodynia in patients with idiopathic intracranial hypertension. Cephalalgia 32(14):1049–1058. https://doi.org/10.1177/0333102412457091

    Article  PubMed  Google Scholar 

  8. Beck AT, Ward CH, Mendelson M et al (1961) An inventory for measuring depression. Arch Gen Psychiatry 4:561–571. https://doi.org/10.1001/archpsyc.1961.01710120031004

    Article  CAS  PubMed  Google Scholar 

  9. Ware JE, Sherbourne CD (1992) The MOS 36 item short form health survey(SF-36) I: conceptional framework and item selection. Med Carem 30:473–480

    Article  Google Scholar 

  10. Karapolat H, Eyigor S, Kirazli Y et al (2010) Reliability, validity, and sensitivity to change of turkish activities-specific balance confidence scale in patients with unilateral peripheral vestibular disease. Int J Rehabil Res 33(1):12–18. https://doi.org/10.1097/mrr.0b013e32832c0d72

    Article  PubMed  Google Scholar 

  11. Jeong SH, Oh SY, Kim HJ et al (2010) Vestibular dysfunction in migraine: effects of associated vertigo and motion sickness. J Neurol 257(6):905–912. https://doi.org/10.1007/s00415-009-5435-5

    Article  PubMed  Google Scholar 

  12. Balcı B, Akdal G (2020) Imbalance, motion sensitivity, anxiety and handicap in vestibular migraine and migraine only patients. Auris Nasus Larinks. https://doi.org/10.1016/j.anl.2020.02.015 (Advance online publication)

    Article  Google Scholar 

  13. Murdin L, Chamberlain F, Cheema S et al (2015) Motion sickness in migraine and vestibular disorders. J Neurol Neurosurg Psychiatry 86(5):585–587. https://doi.org/10.1136/jnnp-2014-308331

    Article  PubMed  Google Scholar 

  14. Atkinson W, Sheldon TA, Shaath N, Whorwell PJ (2004) Food elimination based on IgG antibodies in irritable bowel syndrome: a randomised controlled trial. Gut 53:1459–1464. https://doi.org/10.1136/gut.2003.037697

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  15. Alpay K, Ertas M, Orhan EK, Ustay DK et al (2010) Diet restriction in migraine, based on IgG against foods: a clinical double-blind, randomised, cross-over trial. Cephalalgia 30(7):829–837. https://doi.org/10.1177/0333102410361404

    Article  PubMed  PubMed Central  Google Scholar 

  16. Baldacci F, Lucchesi C, Ulivi M et al (2015) Clinical features associated with ictal osmophobia in migraine. Neurol Sci 36(1):43–46. https://doi.org/10.1007/s10072-014-1903-5

    Article  PubMed  Google Scholar 

  17. Murdin L, Premachandra P, Davies R (2010) Sensory dysmodulation in vestibular migraine: an otoacoustic emission suppression study. Laryngoscope 120(8):1632–1636. https://doi.org/10.1002/lary.21013

    Article  PubMed  Google Scholar 

  18. Takeuti AA, Fávero ML, Zaia EH et al (2019) Auditory brainstem function in women with vestibular migraine: a controlled study. BMC Neurol 19(1):144. https://doi.org/10.1186/s12883-019-1368-5

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  19. Kırkım G, Mutlu B, Olgun Y et al (2017) Comparison of audiological findings in patients with vestibular migraine and migraine. Turk Arch Otorhinolaryngol 55(4):158–161. https://doi.org/10.5152/tao.2017.2609

    Article  PubMed  PubMed Central  Google Scholar 

  20. Park HJ, Viirre E (2010) Vestibular migraine may be an important cause of dizziness/vertigo in perimenopausal period. Med Hypotheses 75(5):409–414. https://doi.org/10.1016/j.mehy.2009.04.054

    Article  CAS  PubMed  Google Scholar 

  21. Akdal G, Özçelik P, Özge A (2020) Vestibular migraine: considered from both the vestibular and the migraine point of view. Neurol Sci Neurophysiol [serial online] 37:41–49. Available at: http://www.nsnjournal.org/text.asp?2020/37/2/41/288421.

  22. Brandt T, Dieterich M (2020) “Excess anxiety” and “less anxiety”: both depend on vestibular function. Curr Opin Neurol 33(1):136–141. https://doi.org/10.1097/WCO.0000000000000771

    Article  PubMed  Google Scholar 

  23. Ten Voorde M, van der Zaag-Loonen HJ, van Leeuwen RB (2012) Dizziness impairs health related quality of life. Qual Life Res 21(6):961–966. https://doi.org/10.1007/s11136-011-0001-x

    Article  PubMed  Google Scholar 

  24. Kutay Ö, Akdal G, Keskinoğlu P et al (2017) Vestibular migraine patients are more anxious than migraine patients without vestibular symptoms. J Neurol 264(Suppl 1):37–41. https://doi.org/10.1007/s00415-017-8439-6

    Article  PubMed  Google Scholar 

Download references

Acknowledgements

Authors thank Prof. Dr. G. M. Halmágyi for linguistic help and comments on the paper.

Funding

This study does not have any funding.

Author information

Authors and Affiliations

  1. Department of Neuroscience, Institute of Health Sciences, Dokuz Eylül University, İzmir, Turkey

    Pınar Özçelik, Koray Koçoğlu & Gülden Akdal

  2. Department of Neurology, Faculty of Medicine, Dokuz Eylül University, İnciraltı/Balçova, İzmir, Turkey

    Vesile Öztürk & Gülden Akdal

  3. Department of Biostatistics and Medical Informatics, Faculty of Medicine, Dokuz Eylül University, İzmir, Turkey

    Pembe Keskinoğlu

Authors
  1. Pınar Özçelik
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Koray Koçoğlu
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Vesile Öztürk
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Pembe Keskinoğlu
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Gülden Akdal
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Gülden Akdal.

Ethics declarations

Conflicts of interest

None of the authors have conflict of interest.

Consent to participate

All of the authors consent to participate.

Consent for publication

All of the authors consent for publication.

Ethics approval

Local ethics committee approved the study. All study procedures have been performed in accordance with the ethical standards laid down in the 1964 Declaration of Helsinki and its later amendments.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Özçelik, P., Koçoğlu, K., Öztürk, V. et al. Characteristic differences between vestibular migraine and migraine only patients. J Neurol 269, 336–341 (2022). https://doi.org/10.1007/s00415-021-10636-0

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00415-021-10636-0

Keywords

Search

Navigation