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Chronic inflammatory demyelinating polyneuropathy: evaluation of the vestibular system with cervical and ocular vestibular evoked myogenic potentials

  • Rhinology
  • Published:
European Archives of Oto-Rhino-Laryngology Aims and scope Submit manuscript

Abstract

Purpose

To investigate the possibility of vestibular damage in a group of patients suffering from chronic inflammatory demyelinating polyneuropathy (CIDP) using a diagnostic protocol including the caloric test, C-VEMPs and O-VEMPs.

Methods

Twenty patients suffering from CIDP (mean age 58.5 years, range 33–80 years; 4 women and 16 men) were investigated. To assess any eventual audio-vestibular involvement, all patients of the study underwent pure tone audiometry, Fitzgerald–Hallpike caloric vestibular test, C-VEMPs and O-VEMPs.

Results

In 11 patients with CIDP values of both O-VEMPs and C-VEMPs were either absent or abnormal. An absent trace at O-VEMPs testing occurred in 36% of these pathological patients, whereas an increase of n10 latency and amplitude was present in the other 64% .

Conclusions

A specific diagnostic protocol including the caloric test, C-VEMPS, O-VEMPS, could be useful when employed for identifying vestibular damage in CIDP patients.

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Funding

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Authors and Affiliations

  1. Department of Organi di Senso, University “Sapienza”, Via Gregorio VII n.80, 00165, Rome, Italy

    Giuseppe Magliulo, Giannicola Iannella, Alessandra Manno, Diletta Angeletti, Annalisa Pace, Giampiero Gulotta & Silvia Gagliardi

  2. Department of Neurology and Psychiatry, University “Sapienza”, Rome, Italy

    Laura Libonati, Emanuela Onesti & Maurizio Inghilleri

  3. Department of Public Health and Infectious Diseases, University “Sapienza, Rome, Italy

    Annarita Vestri & Danilo Alunni Fegatelli

Authors
  1. Giuseppe Magliulo
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  2. Giannicola Iannella
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  3. Alessandra Manno
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  4. Laura Libonati
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  5. Emanuela Onesti
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  6. Annarita Vestri
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  7. Danilo Alunni Fegatelli
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  8. Diletta Angeletti
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  9. Annalisa Pace
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  10. Giampiero Gulotta
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  11. Silvia Gagliardi
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  12. Maurizio Inghilleri
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Corresponding author

Correspondence to Giuseppe Magliulo.

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Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies were in accordance with the ethical standards of the institutional committee of ‘Sapienza’ University and with the 1964 Helsinki declaration.

Informed consent

Informed consent was obtained from all individual participants included in the study.

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Magliulo, G., Iannella, G., Manno, A. et al. Chronic inflammatory demyelinating polyneuropathy: evaluation of the vestibular system with cervical and ocular vestibular evoked myogenic potentials. Eur Arch Otorhinolaryngol 275, 1507–1512 (2018). https://doi.org/10.1007/s00405-018-4981-9

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  • DOI: https://doi.org/10.1007/s00405-018-4981-9

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