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Endoscopic endonasal approach for trigeminal schwannomas: our experience of 39 patients in 10 years

  • Rhinology
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Abstract

Background

The anatomical locations involved in trigeminal schwannomas (TSs) are quite complex. The endoscopic endonasal approach provides a minimal damage access corridor to both anterior and middle skull base for surgery. Given the nerve function recovery and postoperative neurological deterioration varied in different reports, the author demonstrates his surgery tips and the functional outcomes under endoscopic surgery in one single institution.

Methods

A retrospective review of patients with TSs was undertaken to assess the outcome of endoscopic surgery from 2006 to 2016. Clinical features, imaging findings, preoperative/postoperative neurological deficits, surgical approaches and followed up data were collected.

Results

Thirty-nine patients with TSs were included in this study. Surgical approaches include endoscopic medial maxillectomy approach (n = 8), endoscopic endonasal-assisted sublabial transmaxillary approach (n = 27) and endoscopic endonasal-assisted sublabial transmaxillary combined with septectomy (n = 4). Gross total resection and sub-total resection were achieved in 27 and 10 patients, respectively. The most common chief complaint was facial numbness, accounting for 41%, with a resolved rate of 62.5% after treatment. Fifteen patients developed new neurologic symptoms, including facial numbness/pain (n = 9 and 2, respectively), dry eye (n = 3) and mastication weakness (n = 1). Eight of these patients had partial improvement except for patients with dry eye.

Conclusion

Endoscopic endonasal approach represents a safe and effective surgical procedure for TSs in pterygopalatine fossa, infratemporal fossa and even Meckel cave. Tumor resection can be achieved by endoscope with few neurologic deficits and complications.

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References

  1. Hisaoka M, Ohta H, Haratake J, Horie A (1991) Melanocytic schwannoma in the spinal canal. Acta Pathol Jpn 41:685–688

    CAS  PubMed  Google Scholar 

  2. Singh B, Shaha AR (1994) Solitary malignant schwannoma invading the hypoglossal nerve. Ear Nose Throat J 73:842–844 (847–9)

    CAS  Google Scholar 

  3. Wanibuchi M, Fukushima T, Zomordi AR, Nonaka Y, Friedman AH (2012)Trigeminal schwannomas: skull base approaches and operative results in 105 patients. Neurosurgery 70:132–143 (discussion 143–144)

    PubMed  Google Scholar 

  4. Wong BL, Bathala S, Grant D (2017) Laryngeal schwannoma: a systematic review. Eur Arch Otorhinolaryngol 274:25–34

    Article  PubMed  Google Scholar 

  5. Raza SM, Donaldson AM, Mehta A, Tsiouris AJ, Anand VK, Schwartz TH (2014) Surgical management of trigeminal schwannomas: defining the role for endoscopic endonasal approaches. Neurosurg Focus 37:E17

    Article  PubMed  Google Scholar 

  6. Taylor RJ, Patel MR, Wheless SA et al (2014) Endoscopic endonasal approaches to infratemporal fossa tumors: a classification system and case series. Laryngoscope 124:2443–2450

    Article  PubMed  Google Scholar 

  7. Shin SS, Gardner PA, Stefko ST, Madhok R, Fernandez-Miranda JC, Snyderman CH (2011) Endoscopic endonasal approach for nonvestibular schwannomas. Neurosurgery 69:1046–1057 (discussion 1057)

    Article  PubMed  Google Scholar 

  8. Samii M, Alimohamadi M, Gerganov V (2014) Endoscope-assisted retrosigmoid intradural suprameatal approach for surgical treatment of trigeminal schwannomas. Neurosurgery 10(Suppl 4):565–575 (discussion 575)

    Article  PubMed  Google Scholar 

  9. Ramina R, Mattei TA, Soria MG et al (2008)Surgical management of trigeminal schwannomas. Neurosurg Focus 25:E6 (discussion E6)

    Article  PubMed  Google Scholar 

  10. Hasegawa T, Kato T, Kida Y et al (2016) Gamma Knife surgery for patients with facial nerve schwannomas: a multiinstitutional retrospective study in Japan. J Neurosurg 124:403–410

    Article  PubMed  Google Scholar 

  11. Taha JM, Tew JM Jr, van Loveren HR, Keller JT, el-Kalliny M (1995) Comparison of conventional and skull base surgical approaches for the excision of trigeminal neurinomas. J Neurosurg 82:719–725

    Article  CAS  PubMed  Google Scholar 

  12. McCormick PC, Bello JA, Post KD (1988)Trigeminal schwannoma. Surgical series of 14 cases with review of the literature. J Neurosurg 69:850–860

    Article  CAS  PubMed  Google Scholar 

  13. Xu F, Sun X, Hu L et al (2011) Endoscopic surgical treatment of neurogenic tumor in pterygopalatine and infratemporal fossae via extended medial maxillectomy. Acta Otolaryngol 131:161–165

    Article  PubMed  Google Scholar 

  14. Shin M, Kondo K, Hanakita S et al (2017) Endoscopic transsphenoidal anterior petrosal approach for locally aggressive tumors involving the internal auditory canal, jugular fossa, and cavernous sinus. J Neurosurg 126:212–221

    Article  PubMed  Google Scholar 

  15. Zhang Q, Feng K, Ge C, Hongchuan G, Mingchu L (2012) Endoscopic endonasal management of trigeminal schwannomas extending into the infratemporal fossa. J Clin Neurosci 19:862–865

    Article  PubMed  Google Scholar 

  16. Al-Mefty O, Ayoubi S, Gaber E (2002)Trigeminal schwannomas: removal of dumbbell-shaped tumors through the expanded Meckel cave and outcomes of cranial nerve function. J Neurosurg 96:453–463

    Article  PubMed  Google Scholar 

  17. Devaiah AK, Reiersen D, Hoagland T (2013) Evaluating endoscopic and endoscopic-assisted access to the infratemporal fossa: a novel method for assessment and comparison of approaches. Laryngoscope 123:1575–1582

    Article  PubMed  Google Scholar 

  18. Upadhyay S, Dolci RL, Buohliqah L et al (2016) Effect of incremental endoscopic maxillectomy on surgical exposure of the pterygopalatine and infratemporal fossae. J Neurol Surg B Skull Base 77:66–74

    Article  PubMed  Google Scholar 

  19. Fukaya R, Yoshida K, Ohira T, Kawase T (2010)Trigeminal schwannomas: experience with 57 cases and a review of the literature. Neurosurg Rev 34:159–171

    Article  PubMed  Google Scholar 

  20. Karligkiotis A, Turri-Zanoni M, Sica E et al (2016) Role of endoscopic surgery in the management of sinonasal and skull base schwannomas. Head Neck 38(Suppl 1):E2074–E2082

    Article  PubMed  Google Scholar 

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Acknowledgements

This Project is supported by Shanghai Municipal Hospitals’ Rising and Leading Technology Program (No. SHDC12013121).

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Correspondence to Dehui Wang.

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None of the authors have any conflict of interest.

Ethical approval

This study was approved by the ethics committee of Eye, Ear, Nose and Throat Hospital affiliated to Fudan University, Shanghai, China.

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Yang, L., Hu, L., Zhao, W. et al. Endoscopic endonasal approach for trigeminal schwannomas: our experience of 39 patients in 10 years. Eur Arch Otorhinolaryngol 275, 735–741 (2018). https://doi.org/10.1007/s00405-018-4871-1

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