Abstract
Purpose
To determine neonatal birthweight (BW) thresholds for adverse maternal and neonatal outcome following vaginal delivery.
Methods
A retrospective cohort study of all women with singleton pregnancies who underwent vaginal delivery in a university-affiliated tertiary hospital (1996–2015). The association between BW and adverse outcome in neonates with BW ≥ 3500 g (> 90th centile BW at 37 weeks’ gestation) with 100 g-increment groups was explored. Pregnancies complicated by diabetes mellitus, fetal anomalies or cesarean deliveries were excluded. The composite neonatal outcome was defined as shoulder dystocia or brachial plexus injury. The composite maternal outcome was defined as postpartum hemorrhage or third- or fourth-degree perineal tears.
Results
Of the 121,728 deliveries during the study period, 26,920 (22.1%) met inclusion criteria. Of these, 1024 (3.8%) had a composite adverse maternal outcome and 947 (3.5%) had a composite adverse neonatal outcome. The rates of composite maternal outcomes increased significantly only at a BW of 4800 g and above. The composite neonatal outcomes increased significantly only at a BW of 4400 g and above. In multivariate analysis, after subcategorizing our cohort into 3 BW groups [3500–3999 g (control, n = 23,030); 4000–4399 g (n = 3494); ≥ 4400 g (n = 396)], BW was associated with adverse neonatal outcomes in a dose-dependent manner. In the BW ≥ 4400 g group, to prevent one case of shoulder dystocia or Erb’s palsy, 12 cesarean deliveries needed to be performed.
Conclusion
For non-diabetic mothers who deliver vaginally, neonatal BW ≥ 4400 g was associated with a significant increase in adverse neonatal outcomes, whereas neonatal BW ≥ 4800 g was associated with a significant increase in adverse maternal outcomes.
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Funding
All funding for this study was departmental.
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EA, helped design the study, conduct the study, analyze the data, write the manuscript review and edit the manuscript. AB helped conduct the study. SO-Z helped write and edit the manuscript. NM helped conduct the study, reviewed and edited the manuscript. AA helped design the study, conduct the study and analyze the data. EH helped design the study, helped reviewed and edit the manuscript. YY helped design the study, helped conduct the study and helped reviewed and edit the manuscript. LH helped design the study, conduct the study, analyze the data, write the manuscript review and edit the manuscript.
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This study was performed in accordance with the ethical standards of the institutional committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. This study received Institutional review board from Rabin Medical’s Center Helsinki committee. As it was a retrospective study, study formal consent is not required.
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Ashwal, E., Berezowsky, A., Orbach-Zinger, S. et al. Birthweight thresholds for increased risk for maternal and neonatal morbidity following vaginal delivery: a retrospective study. Arch Gynecol Obstet 298, 1123–1129 (2018). https://doi.org/10.1007/s00404-018-4924-0
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DOI: https://doi.org/10.1007/s00404-018-4924-0