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Mortality and morbidity associated with simultaneous bilateral or staged bilateral total knee arthroplasty: a meta-analysis

  • Knee Arthroplasty
  • Published:
Archives of Orthopaedic and Trauma Surgery Aims and scope Submit manuscript

Abstract

Objective

To evaluate the mortality and postoperative morbidity associated with simultaneous bilateral or staged bilateral total knee arthroplasty (TKA).

Methods

We identified eligible studies in PubMed (1980–2010), OVID MEDLINE (1980–2010) and the Cochrane library. Data were extracted and evaluated by two reviewers independently. Data analyses were conducted with Stata 10.0.

Results

Fourteen studies met our inclusion criteria. Combined results showed that the prevalence of mortality [OR = 3.202, 95% CI (1.852–5.537)], mortality at 30 days postoperatively [OR = 5.564, 95% CI (2.392–12.939)] and neurological complications [OR = 2.906, 95% CI (1.200–7.037)] were significantly higher in the population who had undergone simultaneous TKA compared with those who had undergone staged TKA. The prevalence of infection, pulmonary embolism, deep-vein thrombosis, and cardiac complications between the two populations was not significantly different.

Conclusion

Compared with staged bilateral TKA, simultaneous bilateral TKA might carry a higher potential risk of postoperative complications. Patients should be aware of this information when deciding whether to proceed with simultaneous bilateral TKA. The poor quality of the studies calls into question the robustness of the analyses.

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Acknowledgments

This project was supported by a grant from the National Natural Science Foundation of China (Grant No. 30901800).

Conflict of interest

The authors declare that they have no competing interests.

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Corresponding author

Correspondence to Weimin Fan.

Additional information

J. Hu and Y. Liu contributed equally to this work.

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Hu, J., Liu, Y., Lv, Z. et al. Mortality and morbidity associated with simultaneous bilateral or staged bilateral total knee arthroplasty: a meta-analysis. Arch Orthop Trauma Surg 131, 1291–1298 (2011). https://doi.org/10.1007/s00402-011-1287-4

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  • DOI: https://doi.org/10.1007/s00402-011-1287-4

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