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Four-repeat tau-positive Pick body-like inclusions are distinct from classic Pick bodies

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Fig. 1
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References

  1. Dickson DW (1998) Pick’s disease: a modern approach. Brain Pathol 8:339–354

    PubMed  Google Scholar 

  2. Kobayashi T, Ota S, Tanaka K, Ito Y, Hasegawa M, Umeda Y, Motoi Y, Takanashi M, Yasuhara M, Anno M, Mizuno Y, Mori H (2003) A novel L266V mutation of the tau gene causes frontotemporal dementia with a unique tau pathology. Ann Neurol 53:133–137

    Article  PubMed  Google Scholar 

  3. Spillantini MG, Goedert M (1998) Tau protein pathology in neurodegenerative diseases. Trends Neurosci 21:428–433

    Article  PubMed  Google Scholar 

  4. Takauchi S, Mizuhara T, Miyoshi K (1983) Unusual paired helical filaments in progressive supranuclear palsy. Acta Neuropathologica (Berl) 59:225–228

    Google Scholar 

  5. Yasuda M, Maeda K, Hashimoto M, Yamashita H, Ikejiri Y, Bird TD, Tanaka C, Schellenberg GD (1999) A pedigree with a novel presenilin-1 mutation at a residue that is not conserved in presenilin-2. Arch Neurol 56:65–69

    Article  PubMed  Google Scholar 

  6. Zhukareva V, Mann D, Pickering-Brown S, Uryu K, Shuck T, Shah K, Grossman M, Miller BL, Hulette CM, Feinstein SC, Trojanowski JQ, Virginia MYL (2002) Sporadic Pick’s disease: a tauopathy characterized by a spectrum of pathological tau isoform in gray and white matter. Ann Neurol 51:730–739

    Article  PubMed  Google Scholar 

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Acknowledgement

We are grateful to Dr. Kunimasa Arima for excellent advice regarding the ultrastructural study.

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Author notes

  1. Hiroyuki Iwamoto

    Present address: Iwate Prefecture Daito Hospital, Daito-cho, Japan

Authors and Affiliations

  1. Department of Neurology, Juntendo University School of Medicine, 3-1-3 Hongo Bunkyo-ku, 113-8431, Tokyo , Japan

    Yumiko Motoi, Masako Itaya, Yoshikuni Mizuno & Hideo Mori

  2. Department of Neurology, Hatsuishi Hospital, Tokyo, Japan

    Hiroyuki Iwamoto

  3. Fifth Department of Internal Medicine, Fukuoka University, Fukuoka, Tokyo

    Tomonori Kobayashi

  4. Department of Molecular Neurobiology, Tokyo Institute of Psychiatry, Tokyo, Japan

    Masato Hasegawa

  5. Department of Psychiatry and Neurology, Kobe University Graduate School of Medicine, Kobe, Japan

    Minoru Yasuda

Authors
  1. Yumiko Motoi
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  2. Hiroyuki Iwamoto
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  3. Masako Itaya
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  4. Tomonori Kobayashi
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  5. Masato Hasegawa
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  6. Minoru Yasuda
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  7. Yoshikuni Mizuno
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  8. Hideo Mori
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Corresponding author

Correspondence to Yumiko Motoi.

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Motoi, Y., Iwamoto, H., Itaya, M. et al. Four-repeat tau-positive Pick body-like inclusions are distinct from classic Pick bodies. Acta Neuropathol 110, 431–433 (2005). https://doi.org/10.1007/s00401-005-1075-8

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  • DOI: https://doi.org/10.1007/s00401-005-1075-8

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