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„Tight control“ – Forderung nach engmaschiger Kontrolle der rheumatoiden Arthritis

Tight control—Demand for short term control of rheumatoid arthritis

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Zusammenfassung

Die Prognose der rheumatoiden Arthritis (RA) hat sich in den letzten Jahrzehnten deutlich verbessert. Dazu haben im Wesentlichen eine frühere Erkennung, bessere Diagnostik und neue Therapieoptionen wie optimierter Einsatz von klassischen DMARDs („disease modifying antirheumatic drugs“) und Biologika beigetragen. Weitere Faktoren waren auch eine frühere Intervention, eine verbesserte Verfügbarkeit von Informationen und Analysen und sicher auch die Standardisierung der Versorgung (z. B. Leitlinien). Ein zusätzlicher wichtiger Baustein ist eine engmaschige Kontrolle der Krankheitsaktivität, um die Therapie rechtzeitig anpassen zu können und somit Schäden zu verhindern. Die Forderung nach dieser Kontrolle, im englischen „tight control“, ist Gegenstand dieses Beitrags.

Abstract

The prognosis of rheumatoid arthritis (RA) has been significantly improved in recent decades. This is mainly due to earlier detection, better diagnostics and new treatment options, such as the optimized use of classical disease-modifying antirheumatic drugs (DMARD) and biologicals. Other factors involved were earlier intervention, improved availability of information and analyses and certainly also standardization of care (e.g. guidelines). An additional important component is close monitoring of disease activity in order to be able to adapt the treatment in a timely manner and thus prevent damage. The demand for tight control is the subject of this article.

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Authors and Affiliations

  1. Poliklinik und Funktionsbereich für Rheumatologie und Hiller Forschungszentrum, Universitätsklinikum Düsseldorf, Moorenstr. 5, 40225, Düsseldorf, Deutschland

    M. Schneider

  2. Medizinische Klinik mit Schwerpunkt Rheumatologie und Klinische Immunologie, Charité – Universitätsmedizin Berlin, Charitéplatz 1, 10117, Berlin, Deutschland

    G.-R. Burmester

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Interessenkonflikt

M. Schneider weist auf folgende Beziehungen hin: Projektunterstützung (von Abbvie, GSK, UCB) und Beratung/Vorträge (für Abbvie, Astra-Zeneca, Biogen, BMS, Boehringer-Ingelheim, Celgene, Chugai, GSK, Janssen-Cilag, Lilly, MSD, Novartis, Pfizer, Protagen, Roche, Sanofi-Aventis, UCB). G.‑R. Burmester gibt an, dass kein Interessenkonflikt besteht.

Für diesen Beitrag wurden von den Autoren keine Studien an Menschen oder Tieren durchgeführt. Für die aufgeführten Studien gelten die jeweils dort angegebenen ethischen Richtlinien.

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M. Schneider, Düsseldorf

G.-R. Burmester, Berlin

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Schneider, M., Burmester, GR. „Tight control“ – Forderung nach engmaschiger Kontrolle der rheumatoiden Arthritis. Z Rheumatol 78, 404–412 (2019). https://doi.org/10.1007/s00393-019-0631-x

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