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Appendix orifice polyps: a study of 691 lesions at a single institution

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International Journal of Colorectal Disease Aims and scope Submit manuscript

Abstract

Purpose

Data on the management of appendix orifice lesions are limited. We present our experience on the management of appendix orifice lesions focusing on the range of size, histology, treatment, and outcomes for polyps at the appendix orifice.

Methods

Retrospective descriptive study at a tertiary referral center. Patients: Those having appendix orifice lesion removed and sent for histology between 2000 and 2017. Interventions(s): Polypectomy, surgery. Main outcome measures: Polyp size, shape, histology, treatment.

Results

In total, 691 patients matched our inclusion criteria. Screening was the most common indication for colonoscopy (49.1%). Mean size was 10.1 mm. The most common excision method was cold biopsy forceps (36.3%), followed by hot snare (9.3%), cold snare (8.5%), jumbo cold forceps (6.7%), hot biopsy (6.8%), and endoscopic mucosal resection (EMR)/endoscopic submucosal dissection (ESD) (4%). Recurrence was seen in 19/184 (10.3%) patients. Index polyps ≥ 10 mm had a significantly higher risk of recurrence compared to those ≤ 5 mm (odds ratio 3.2 95% CI 1.1–9.2, p = 0.027). None of the patients had complications. Surgery was performed in 45/691 (6.5%). Polyps > 5 mm (41/45) were more likely to require surgery than polyps ≤ 5 mm (4/45 6.67%), p < 0.001.

Limitations

Retrospective study.

Conclusion

Appendix orifice polyps can usually be managed by conventional endoscopic polypectomy methods without the need for ESD.

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Authors and Affiliations

Authors

Contributions

Both authors contributed by:

• Substantial contributions to the conception or design of the work; or the acquisition, analysis, or interpretation of data for the work;

• Drafting the work or revising it critically for important intellectual content;

• Final approval of the version to be published;

• Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Corresponding author

Correspondence to James M. Church.

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The authors declare that they have no conflict of interest.

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This manuscript has been accepted as a poster presentation in ASCRS Annual Scientific Meeting, Nashville, TN, May19–23, 2018

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Hassab, T.H., Church, J.M. Appendix orifice polyps: a study of 691 lesions at a single institution. Int J Colorectal Dis 34, 711–718 (2019). https://doi.org/10.1007/s00384-019-03251-z

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  • DOI: https://doi.org/10.1007/s00384-019-03251-z

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