Abstract
The term meningocele manqué (MM) was coined in 1972 to describe a broad range of surgical findings characterized by intradural bands tethering neural structures to the dorsal dura. Over the following decades, reports continued to lump intradural tethering bands associated with a variety of comorbidities under the umbrella term MM. In more recent years, disorders previously called MM have been identified as embryologically distinct and were reclassified. While this sectioning continues, there remains a set of intradural tethering disorders for which no better term than MM exists. Herein, we comprehensively review the literature surrounding MM, including embryological disorders, clinical, radiographic, and surgical presentation, as well as alternative classification methods and MM treatment.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
James CCM, Lassman LP (1972) Spinal dysraphism: spina bifida occulta. Butterworth-Heinemann, Oxford
Lassman LP, James CC (1977) Meningocoele manque. Childs Brain 3:1–11
Kriss VM, Kriss TC, Warf BC (1996) Dorsal tethering bands of the meningocele manque: sonographic findings. AJR Am J Roentgenol 167:1293–1294
Steinbok P (1995) Dysraphic lesions of the cervical spinal cord. Neurosurg Clin N Am 6:367–376
Tubbs RS, McGirt MJ, Warder DE, Oakes WJ (2003) Neurological presentation and long-term outcome following operative intervention in patients with meningocele manque. Br J Neurosurg 17:230–233
Pang D, Zovickian J, Oviedo A, Moes GS (2010) Limited dorsal myeloschisis: a distinctive clinicopathological entity. Neurosurgery 67:1555–1579 discussion 1579-1580
Rajpal S, Salamat MS, Tubbs RS, Kelly DR, Oakes WJ, Iskandar BJ (2007) Tethering tracts in spina bifida occulta: revisiting an established nomenclature. J Neurosurg Spine 7:315–322
Pang D (2001) Ventral tethering in split cord malformation. Neurosurg Focus 10:e6
French B (1996) Embryological aspects of the tethered cord syndrome and its relationship to spinal dysraphism. American Association of Neurological Surgeons
Hertzler DA 2nd, DePowell JJ, Stevenson CB, Mangano FT (2010) Tethered cord syndrome: a review of the literature from embryology to adult presentation. Neurosurg Focus 29:E1
Dias MS, Walker ML (1992) The embryogenesis of complex dysraphic malformations: a disorder of gastrulation? Pediatr Neurosurg 18:229–253
Pang D, Dias MS, Ahab-Barmada M (1992) Split cord malformation: part I: a unified theory of embryogenesis for double spinal cord malformations. Neurosurgery 31:451–480
Kaffenberger DA, Heinz ER, Oakes JW, Boyko O (1992) Meningocele manqué: radiologic findings with clinical correlation. Am J Neuroradiol 13:1083–1088
Schropp C, Sörensen N, Collmann H, Krauss J (2006) Cutaneous lesions in occult spinal dysraphism—correlation with intraspinal findings. Childs Nerv Syst 22:125–131
Nishimoto H, Kurihara J, Kishimoto H, Takezawa Y (2006) Surgical and pathological findings of meningocele manque. Shoni No Noshinkei 31:432–433
Anderson FM (1975) Occult spinal dysraphism: a series of 73 cases. Pediatrics 55:826–835
Cochrane DD, Haslam RH, Myles ST (1990) Cervical neuroschisis and meningocoele manque in type I (no neck) Klippel-Feil syndrome. Pediatr Neurosurg 16:174–178
Holtzman RN, Stein BM (1985) The tethered spinal cord. Thieme-Stratton Corp
Iskandar BJ, Oakes J, McLaughlin C, Osumi AK, Tien RD (1994) Terminal syringohydromyelia and occult spinal dysraphism. J Neurosurg 81:513–519
van Aalst J, Beuls EA, Cornips EM, van Straaten HW, Boselie AF, Rijkers K, Weber JW, Vles JS (2009) The spinal dermal-sinus-like stalk. Childs Nerv Syst 25:191–197
Martinez-Lage JF, Almagro MJ, Ferri-Niguez B, Izura Azanza V, Serrano C, Domenech E (2011) Spinal dermal sinus and pseudo-dermal sinus tracts: two different entities. Childs Nerv Syst 27:609–616
Eibach S, Moes G, Zovickian J, Pang D (2017) Limited dorsal myeloschisis associated with dermoid elements. Childs Nerv Syst 33:55–67
Lee SM, Cheon JE, Choi YH, Kim IO, Kim WS, Cho HH, Lee JY, Wang KC (2017) Limited dorsal myeloschisis and congenital dermal sinus: comparison of clinical and MR imaging features. AJNR am J Neuroradiol 38:176–182
Pang D, Zovickian J, Wong ST, Hou YJ, Moes GS (2013) Limited dorsal myeloschisis: a not-so-rare form of primary neurulation defect. Childs Nerv Syst 29:1459–1484
Cornips EM, Weber JW, Vles JS, van Aalst J (2011) Pseudo-dermal sinus tract or spinal dermal-sinus-like stalk? Childs Nerv Syst 27:1189–1191 author reply 1193
De Vloo P, Lagae L, Sciot R, Demaerel P, van Loon J, Van Calenbergh F (2013) Spinal dermal sinuses and dermal sinus-like stalks analysis of 14 cases with suggestions for embryologic mechanisms resulting in dermal sinus-like stalks. Eur J Paediatr Neurol 17:575–584
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
The authors declare no conflicts of interest.
Rights and permissions
About this article
Cite this article
Schmidt, C., Bryant, E., Iwanaga, J. et al. Meningocele manqué: a comprehensive review of this enigmatic finding in occult spinal dysraphism. Childs Nerv Syst 33, 1065–1071 (2017). https://doi.org/10.1007/s00381-017-3472-4
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00381-017-3472-4