Skip to main content

Advertisement

Log in

Critical analysis of urethroplasty for male anterior urethral stricture: a single-center experience

  • Original Article
  • Published:
World Journal of Urology Aims and scope Submit manuscript

Abstract

Purpose

Urethroplasty is the most effective treatment method for anterior urethral strictures, which constitute an important health concern for males. This study aims to investigate factors that may predict treatment failure following urethroplasty for anterior urethral strictures and evaluate outcomes of different urethroplasty techniques.

Methods

This retrospective study utilized univariate and multivariate analyses to identify factors affecting treatment success following different urethroplasty techniques performed by a single surgeon on male patients with anterior urethral strictures. Surgical outcomes of different urethroplasty techniques were evaluated individually.

Results

Urethroplasty procedures performed on 244 patients with a mean age of 54 years and a mean stricture length of 4.7 cm produced a success rate of 79.1%. Multivariate analyses identified stricture length and number of previous internal urethrotomy procedures as factors predicting urethroplasty success (HR 1.265, 95% CI 1.129–1.416, p < 0.001 and HR 1.188, 95% CI 1.038–1.361, p = 0.013, respectively). The eight surgical techniques used by the surgeon produced success rates that varied between 50% and 86.2%.

Conclusion

Urethroplasty can offer satisfactory outcomes for anterior urethral strictures. Accordingly, a longer stricture length and greater number of previous internal urethrotomy procedures were associated with greater risk for urethroplasty failure. Moreover, urethroplasty techniques must be selected based on multifactorial evaluation and performed at experienced centers.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  1. Rourke K, Hickle J (2012) The clinical spectrum of the presenting signs and symptoms of anterior urethral stricture: detailed analysis of a single institutional cohort. Urology 79(5):1163–1167. https://doi.org/10.1016/j.urology.2012.01.044

    Article  PubMed  Google Scholar 

  2. Santucci RA, Joyce GF, Wise M (2007) Male urethral stricture disease. J Urol 177(5):1667–1674. https://doi.org/10.1016/j.juro.2007.01.041

    Article  PubMed  Google Scholar 

  3. Liu JS, Hofer MD, Oberlin DT, Milose J, Flury SC, Morey AF, Gonzalez CM (2015) Practice patterns in the treatment of urethral stricture among american urologists: a paradigm change? Urology 86(4):830–834. https://doi.org/10.1016/j.urology.2015.07.020

    Article  PubMed  Google Scholar 

  4. Wessells H, Angermeier KW, Elliott S, Gonzalez CM, Kodama R, Peterson AC, Reston J, Rourke K, Stoffel JT, Vanni AJ, Voelzke BB, Zhao L, Santucci RA (2017) Male urethral stricture: American urological association guideline. J Urol 197(1):182–190. https://doi.org/10.1016/j.juro.2016.07.087

    Article  PubMed  Google Scholar 

  5. Andrich DE, Dunglison N, Greenwell TJ, Mundy AR (2003) The long-term results of urethroplasty. J Urol 170(1):90–92. https://doi.org/10.1097/01.ju.0000069820.81726.00

    Article  CAS  PubMed  Google Scholar 

  6. Barbagli G, Montorsi F, Balo S, Sansalone S, Loreto C, Butnaru D, Bini V, Lazzeri M (2018) Treatments of 1242 bulbar urethral strictures: multivariable statistical analysis of results. World J Urol. https://doi.org/10.1007/s00345-018-2481-6

    Article  PubMed  Google Scholar 

  7. Akyuz M, Tokuc E, Ozsoy E, Koca O, Kanberoglu H, Ozturk M, Topaktas R (2018) Characteristics of the urethroplasty and our approach-Experience in patients with urethral stricture. Turk J Urol 45(4):307–311. https://doi.org/10.5152/tud.2018.68700

    Article  PubMed  PubMed Central  Google Scholar 

  8. Bayne DB, Gaither TW, Awad MA, Murphy GP, Osterberg EC, Breyer BN (2017) Guidelines of guidelines: a review of urethral stricture evaluation, management, and follow-up. Transl Androl Urol 6(2):288–294. https://doi.org/10.21037/tau.2017.03.55

    Article  PubMed  PubMed Central  Google Scholar 

  9. Chapman D, Kinnaird A, Rourke K (2017) Independent predictors of stricture recurrence following urethroplasty for isolated bulbar urethral strictures. J Urol 198(5):1107–1112. https://doi.org/10.1016/j.juro.2017.05.006

    Article  PubMed  Google Scholar 

  10. Fuehner C, Dahlem R, Fisch M, Vetterlein MW (2019) Update on managing anterior urethral strictures. Indian J Urol 35(2):94–100. https://doi.org/10.4103/iju.IJU_52_19

    Article  PubMed  PubMed Central  Google Scholar 

  11. Eltahawy EA, Virasoro R, Schlossberg SM, McCammon KA, Jordan GH (2007) Long-term followup for excision and primary anastomosis for anterior urethral strictures. J Urol 177(5):1803–1806. https://doi.org/10.1016/j.juro.2007.01.033

    Article  PubMed  Google Scholar 

  12. Andrich DE, Mundy AR (2012) Non-transecting anastomotic bulbar urethroplasty: a preliminary report. BJU Int 109(7):1090–1094. https://doi.org/10.1111/j.1464-410X.2011.10508.x

    Article  PubMed  Google Scholar 

  13. Bugeja S, Andrich DE, Mundy AR (2015) Non-transecting bulbar urethroplasty. Transl Androl Urol 4(1):41–50. https://doi.org/10.3978/j.issn.2223-4683.2015.01.07

    Article  PubMed  PubMed Central  Google Scholar 

  14. Mundy AR, Stephenson TP (1988) Pedicled preputial patch urethroplasty. Br J Urol 61(1):48–52

    Article  CAS  PubMed  Google Scholar 

  15. Morey AF, McAninch JW (1996) When and how to use buccal mucosal grafts in adult bulbar urethroplasty. Urology 48(2):194–198. https://doi.org/10.1016/S0090-4295(96)00154-9

    Article  CAS  PubMed  Google Scholar 

  16. Barbagli G, Selli C, Tosto A, Palminteri E (1996) Dorsal free graft urethroplasty. J Urol 155(1):123–126

    Article  CAS  PubMed  Google Scholar 

  17. Asopa HS, Garg M, Singhal GG, Singh L, Asopa J, Nischal A (2001) Dorsal free graft urethroplasty for urethral stricture by ventral sagittal urethrotomy approach. Urology 58(5):657–659

    Article  CAS  PubMed  Google Scholar 

  18. Kulkarni S, Barbagli G, Sansalone S, Lazzeri M (2009) One-sided anterior urethroplasty: a new dorsal onlay graft technique. BJU Int 104(8):1150–1155. https://doi.org/10.1111/j.1464-410X.2009.08590.x

    Article  PubMed  Google Scholar 

  19. Santucci R, Eisenberg L (2010) Urethrotomy has a much lower success rate than previously reported. J Urol 183(5):1859–1862. https://doi.org/10.1016/j.juro.2010.01.020

    Article  PubMed  Google Scholar 

  20. Waxman SW, Morey AF (2006) Management of urethral strictures. Lancet 367(9520):1379–1380. https://doi.org/10.1016/S0140-6736(06)68592-9

    Article  PubMed  Google Scholar 

  21. Mundy AR (1999) Pelvic fracture injuries of the posterior urethra. World J Urol 17(2):90–95

    Article  CAS  PubMed  Google Scholar 

  22. Kessler TM, Schreiter F, Kralidis G, Heitz M, Olianas R, Fisch M (2003) Long-term results of surgery for urethral stricture: a statistical analysis. J Urol 170(3):840–844. https://doi.org/10.1097/01.ju.0000080842.99332.94

    Article  PubMed  Google Scholar 

  23. Kulkarni SB, Bhatiyal HS, Sharma G, Dubey D, Khattar N, Panda A, Dangi A, Joshi P (2018) Urological society of India guidelines on urethral stricture. https://www.usi.org.in/New/Spe_pdf/USI%20Stricture%20Guidelines%20-Dec%202018%20. Accessed Dec 2018

  24. Breyer BN, McAninch JW, Whitson JM, Eisenberg ML, Mehdizadeh JF, Myers JB, Voelzke BB (2010) Multivariate analysis of risk factors for long-term urethroplasty outcome. J Urol 183(2):613–617. https://doi.org/10.1016/j.juro.2009.10.018

    Article  PubMed  Google Scholar 

  25. Horiguchi A (2017) Substitution urethroplasty using oral mucosa graft for male anterior urethral stricture disease: current topics and reviews. Int J Urol 24(7):493–503. https://doi.org/10.1111/iju.13356

    Article  PubMed  Google Scholar 

  26. Dubey D, Vijjan V, Kapoor R, Srivastava A, Mandhani A, Kumar A, Ansari MS (2007) Dorsal onlay buccal mucosa versus penile skin flap urethroplasty for anterior urethral strictures: results from a randomized prospective trial. J Urol 178(6):2466–2469. https://doi.org/10.1016/j.juro.2007.08.010

    Article  PubMed  Google Scholar 

  27. Onol FF, Bindayi A, Tahra A, Basibuyuk I, Onol SY (2017) Turkish validation of the urethral stricture surgery specific patient-reported outcome measure (USS-PROM) with supplemental assessment of erectile function and morbidity due to oral graft harvesting. Neurourol Urodyn 36(8):2089–2095. https://doi.org/10.1002/nau.23243

    Article  PubMed  Google Scholar 

  28. Vasudeva P, Nanda B, Kumar A, Kumar N, Singh H, Kumar R (2015) Dorsal versus ventral onlay buccal mucosal graft urethroplasty for long-segment bulbar urethral stricture: a prospective randomized study. Int J Urol 22(10):967–971. https://doi.org/10.1111/iju.12859

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Contributions

FY was involved in the protocol development, data collection, data analysis, and manuscript writing and editing. IK was involved in the protocol development, data collection, data analysis, and manuscript writing.

Corresponding author

Correspondence to Ibrahim Kartal.

Ethics declarations

Conflict of interest

The author declares that they have no competing interests.

Ethical approval

This study has been approved by the appropriate institutional research ethics committee and has been performed in accordance with the ethical standards as laid down in the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Yalçınkaya, F., Kartal, I. Critical analysis of urethroplasty for male anterior urethral stricture: a single-center experience. World J Urol 38, 2313–2319 (2020). https://doi.org/10.1007/s00345-019-03014-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00345-019-03014-z

Keywords

Navigation