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On-line monitoring of cyclotron target-gas output by means of tunable lead salt diode laser absorption spectroscopy

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Abstract

We demonstrate what is, to our knowledge, the first use of mid-infrared laser absorption spectroscopy for trace-gas measurements of cyclotron target outputs used for the generation of radioactive carbon-11 in positron emission tomography (PET). The spectrometer was based upon a liquid-nitrogen-cooled lead salt diode laser generating single-mode radiation in the wavenumber range of 2230–2240 cm−1. The sample flowed to a multiple-pass optical cell with a total path length of 15.23 m and the laser radiation was detected by two liquid-nitrogen-cooled InSb photodetectors. We present the results of CO, N2O and CO2 measurements on PET trace cyclotron output and discuss future work on 11CO and 11CO2 detection.

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Authors and Affiliations

  1. TDL Sensors Ltd, Core Technology Facility, 46 Grafton St., Manchester, M13 9NT, UK

    V. L. Kasyutich

  2. Wolfson Molecular Imaging Centre, University of Manchester, 27 Palatine Rd., Manchester, M20 3LJ, UK

    A. McMahon & T. Barnhart

  3. School of Chemical Engineering and Analytical Science, University of Manchester, P.O. Box 88, Manchester, M60 1QD, UK

    P. A. Martin

Authors
  1. V. L. Kasyutich
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  2. A. McMahon
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  3. T. Barnhart
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  4. P. A. Martin
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Correspondence to V. L. Kasyutich.

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Kasyutich, V.L., McMahon, A., Barnhart, T. et al. On-line monitoring of cyclotron target-gas output by means of tunable lead salt diode laser absorption spectroscopy. Appl. Phys. B 93, 701–711 (2008). https://doi.org/10.1007/s00340-008-3222-0

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  • DOI: https://doi.org/10.1007/s00340-008-3222-0

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