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Feasibility of contrast material volume reduction in coronary artery imaging using 320-slice volume CT

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Abstract

Objective

To assess reduced volumes of contrast agent on image quality for coronary computed tomography angiography (CCTA) by using single-beat cardiac imaging with 320-slice CT.

Materials and methods

Forty consecutive male patients (mean age: 55.8 years) undergoing CCTA with body weight ≤85 kg, heart rate ≤65 bpm, and ejection fraction ≥55% were included. Image acquisition protocol was standardized (120 kV, 400 mA, and prospective ECG-triggered single-beat nonspiral CCTA). Patients were randomly assigned to one of four groups (G1: received 40 ml, G2: 50 ml, G3: 60 ml, G4: 70 ml). Groups were compared with respect to aortic attenuation, image noise, and image quality.

Results

CT values (mean ± standard deviation) in the aortic root were measured as 423 ± 38 HU in G1, and 471 ± 68, 463 ± 60, and 476 ± 78 HU in G2-4, respectively. There were no statistically significant differences in attenuation among the groups (P > 0.068). All 40 CT datasets were rated diagnostic, and image noise and image quality were not statistically different among groups.

Conclusion

Using 320-slice volume CT, diagnostic image quality can be achieved with 40 ml of contrast material in CCTA in patients with normal body weight, cardiac function, and low heart rate.

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Correspondence to Patrick A. Hein.

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Hein, P.A., May, J., Rogalla, P. et al. Feasibility of contrast material volume reduction in coronary artery imaging using 320-slice volume CT. Eur Radiol 20, 1337–1343 (2010). https://doi.org/10.1007/s00330-009-1692-z

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  • DOI: https://doi.org/10.1007/s00330-009-1692-z

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