Skip to main content
Log in

Asymmetric dimethylarginine levels in essential thrombocythemia—a retrospective analysis

  • Letter to the Editor
  • Published:
Annals of Hematology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Tefferi A, Vardiman JW (2008) Classification and diagnosis of myeloproliferative neoplasms: the 2008 World Health Organization criteria and point-of-care diagnostic algorithms. Leukemia 22(1):14–22. doi:10.1038/sj.leu.2404955

    Article  PubMed  CAS  Google Scholar 

  2. Cortelazzo S, Viero P, Finazzi G, D’Emilio A, Rodeghiero F, Barbui T (1990) Incidence and risk factors for thrombotic complications in a historical cohort of 100 patients with essential thrombocythemia. J Clin Oncol 8(3):556–562

    PubMed  CAS  Google Scholar 

  3. Harrison CN, Donohoe S, Carr P, Dave M, Mackie I, Machin SJ (2002) Patients with essential thrombocythaemia have an increased prevalence of antiphospholipid antibodies which may be associated with thrombosis. Thromb Haemost 87(5):802–807

    PubMed  CAS  Google Scholar 

  4. Gisslinger H, Mullner M, Pabinger I, Heis-Vahidi-Fard N, Gisslinger B, Brichta A, Bachleitner-Hofmann T, Mannhalter C (2005) Mutation of the prothrombin gene and thrombotic events in patients with polycythemia vera or essential thrombocythemia: a cohort study. Haematologica 90(3):408–410

    PubMed  CAS  Google Scholar 

  5. Gisslinger H, Rodeghiero F, Ruggeri M, Heis-Vahidi Fard N, Mannhalter C, Papagiannopoulos M, Rintelen C, Lalouschek W, Knobl P, Lechner K, Pabinger I (1999) Homocysteine levels in polycythaemia vera and essential thrombocythaemia. Br J Haematol 105(2):551–555

    Article  PubMed  CAS  Google Scholar 

  6. Ruggeri M, Gisslinger H, Tosetto A, Rintelen C, Mannhalter C, Pabinger I, Heis N, Castaman G, Missiaglia E, Lechner K, Rodeghiero F (2002) Factor V Leiden mutation carriership and venous thromboembolism in polycythemia vera and essential thrombocythemia. Am J Hematol 71(1):1–6. doi:10.1002/ajh.10153

    Article  PubMed  CAS  Google Scholar 

  7. Lussana F, Caberlon S, Pagani C, Kamphuisen PW, Buller HR, Cattaneo M (2009) Association of V617F Jak2 mutation with the risk of thrombosis among patients with essential thrombocythaemia or idiopathic myelofibrosis: a systematic review. Thromb Res 124:409–417. doi:10.1016/j.thromres.2009.02.004

    Article  PubMed  CAS  Google Scholar 

  8. Carobbio A, Finazzi G, Guerini V, Spinelli O, Delaini F, Marchioli R, Borrelli G, Rambaldi A, Barbui T (2007) Leukocytosis is a risk factor for thrombosis in essential thrombocythemia: interaction with treatment, standard risk factors, and JAK2 mutation status. Blood 109(6):2310–2313. doi:10.1182/blood-2006-09-046342

    Article  PubMed  CAS  Google Scholar 

  9. Kielstein JT, Boger RH, Bode-Boger SM, Schaffer J, Barbey M, Koch KM, Frolich JC (1999) Asymmetric dimethylarginine plasma concentrations differ in patients with end-stage renal disease: relationship to treatment method and atherosclerotic disease. J Am Soc Nephrol 10(3):594–600

    PubMed  CAS  Google Scholar 

  10. Teerlink T, Nijveldt RJ, de Jong S, van Leeuwen PA (2002) Determination of arginine, asymmetric dimethylarginine, and symmetric dimethylarginine in human plasma and other biological samples by high-performance liquid chromatography. Anal Biochem 303(2):131–137. doi:10.1006/abio.2001.5575

    Article  PubMed  CAS  Google Scholar 

  11. Mittermayer F, Namiranian K, Pleiner J, Schaller G, Wolzt M (2004) Acute Escherichia coli endotoxaemia decreases the plasma l-arginine/asymmetrical dimethylarginine ratio in humans. Clin Sci (Lond) 106(6):577–581. doi:10.1042/CS20030363

    Article  CAS  Google Scholar 

  12. Neunteufl T, Heher S, Stefenelli T, Pabinger I, Gisslinger H (2001) Endothelial dysfunction in patients with polycythaemia vera. Br J Haematol 115(2):354–359

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Heinz Gisslinger.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Massera, D., Mittermayer, F., Gisslinger, B. et al. Asymmetric dimethylarginine levels in essential thrombocythemia—a retrospective analysis. Ann Hematol 90, 1105–1106 (2011). https://doi.org/10.1007/s00277-010-1127-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00277-010-1127-6

Keywords

Navigation