Skip to main content
SpringerLink
Log in

Doppelsensibilisierung auf PR-10- und PR-14-Proteine

Double sensitization to PR10 and PR-14 proteins

  • Kurzkasuistiken
  • Published:
Der Hautarzt Aims and scope Submit manuscript

Zusammenfassung

Eine Patientin mit bekanntem oralem Allergiesyndrom auf Haselnüsse und Pfirsiche entwickelte eine Anaphylaxie nach Verzehr von Haselnüssen und Pfirsichen. Obschon Anaphylaxien auf Bet-v1-Homologe beschrieben sind, zeigte sich in der weiteren Diagnostik eine Sensibilisierung auf Lipidtransferproteine, die für ihre schwereren Reaktionen bekannt sind. Doppelsensibilisierungen auf sowohl PR-10- als auch PR-14-Proteine sollten mit untersucht werden und scheinen auch in unseren Breitengraden zunehmend bekannt zu werden.

Abstract

A patient with mild oral allergy syndrome presented with a history of anaphylaxis induced by both hazelnuts and peaches. The ensuing work-up showed a double sensitization to proteins in both pathogenesis-related group 10 (e.g. Bet v1, Cor a1, Pru p1) and 14 (e.g. Pru p3, Cor a8). Such double sensitization profiles are increasingly being recognized in Europe.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Literatur

  1. Salcedo G, Sanchez-Monge R, Barber D, Diaz-Perales A (2007) Plant non-specific lipid transfer proteins: an interface between plant defence and human allergy. Biochim Biophys Acta 1771:781–791

    Article  CAS  PubMed  Google Scholar 

  2. Fernandez-Rivaz M, Bolhaar S, Gonzalez-Mancebo E et al (2006) Apple allergy across Europe: how allergen sentization profiles determine the clinical expression of allergies to plant foods. J Allergy Clin Immunol 108:481–488

    Article  Google Scholar 

  3. Garcia BE, Lizaso MT (2011) Cross-reactivity syndromes in food allergy. J Investig Allergol Clin Immunol 21:162–170

    CAS  PubMed  Google Scholar 

  4. Pastorello EA, Farioli L, Pravettoni V et al (2011) Pru p3- sensitised Italian peach-allergic patients are less likely to develop severe symptoms when also presenting IgE antibodies to Pru p1 and Pru p4. Int Arch Allergy Immunol 156:362–372

    Article  CAS  PubMed  Google Scholar 

Download references

Einhaltung ethischer Richtlinien

Interessenkonflikt

L. Vanstreels, G. Balakirski, S. Röseler, G. Wurpts, M. Megahed, J.M. Baron und H.F. Merk geben an, dass kein Interessenkonflikt besteht.

Dieser Beitrag beinhaltet keine Studien an Menschen oder Tieren.

Author information

Authors and Affiliations

  1. Klinik für Dermatologie und Allergologie, Universitätsklinikum der RWTH Aachen, Pauwelsstr. 30, 52074, Aachen, Deutschland

    L. Vanstreels, G. Balakirski, S. Röseler, G. Wurpts, M. Megahed, J.M. Baron & H.F. Merk

Authors
  1. L. Vanstreels
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. G. Balakirski
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. S. Röseler
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. G. Wurpts
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. M. Megahed
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. J.M. Baron
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. H.F. Merk
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to L. Vanstreels.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Vanstreels, L., Balakirski, G., Röseler, S. et al. Doppelsensibilisierung auf PR-10- und PR-14-Proteine. Hautarzt 65, 1017–1019 (2014). https://doi.org/10.1007/s00105-014-3540-6

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00105-014-3540-6

Schlüsselwörter

Keywords

Search

Navigation