Abstract
Five pentacyclic triterpenoids, oleanolic acid (1), hederagenin (2), ursolic acid (3), tormentic acid (4) and myrianthic acid (5), were isolated from the methanol extract of the leaves ofCampsis grandiflora, and structures of the compounds were established by the spectroscopic methods. Compounds2,3,4, and5 were isolated for the first time from the genusCampsis. All of the compounds (IC50: 45.3, 32.8, 82.6, 42.9 and 46.2 μM respectively) were as equivalently inhibitive as acetylsalicylic acid (IC50: 57.0 μM) on epinephrine induced platelet aggregation.
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Jin, J.L., Lee, Y.Y., Heo, J.E. et al. Anti-platelet pentacyclic triterpenoids from leaves ofcampsis grandiflora . Arch Pharm Res 27, 376–380 (2004). https://doi.org/10.1007/BF02980076
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DOI: https://doi.org/10.1007/BF02980076