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Interaction of drugs with microcrystalline cellulose at the molecular and supermolecular levels

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Abstract

Various drug compositions based on plant substances (allapinin and microcrystalline cellulose (MCC) have been studied before and after micronization with the aid of x-ray-diffraction, IR-spectroscopic, electronmicroscopic and ESR methods of investigation. It has been shown that during the production of the drug compositions a physicochemical intermolecular interaction takes place that ensures a prolongation effect.

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References

  1. Trakman et al., in: Proceedings of the Second All-Union Congress of Pharmacists [in Russian], Riga, September 17–20 (1974), p. 54.

  2. F. N. Kaputskii and T. L. Yurikovich, Drug Preparations Based on Cellulose [in Russian], Minsk (1989), p. 111.

  3. M. Muzik M. Renula, and G. Struskova, Farm. Obz.,59, No. 4, 151 (1990).

    Google Scholar 

  4. R. G. Zhbankov, Infrared Spectra and the Structure of Carbohydrates [in Russian] Nauka i Tekhnika, Minsk (1972), p. 456.

    Google Scholar 

  5. B. A. Tel'nov, M. Yu. Yunusov, and S. Yu. Yunusov, Khim. Prir. Soedin, 583, (1979).

  6. V. P. Karlivan, Methods of Investigating Cellulose [in Russian], Zinatne, Riga (1981), p. 84.

    Google Scholar 

  7. G. V. Nikonovich and Kh. U. Usmanov, Electron Microscopy [in Russian], Tashkent (1962).

  8. L. A. Blyumenfel'd, V. V. Voevodskii, and A. G. Semenov, Applications of Electron Spin Resonance in Chemistry [in Russian], Novosibirsk (1962).

  9. State Pharmacopeia [in Russian], Eleventh ed., No. 2, Meditsina, Moscow (1987), p. 156.

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Authors
  1. N. D. Burkhanova
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  2. S. M. Yugai
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  3. S. S. Khalikov
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  4. M. M. Turganov
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  5. S. A. Muratova
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  6. G. V. Nikonovich
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  7. Kh. N. Aripov
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Additional information

Institute of the Chemistry and Physics of Polymers, Academy of Sciences of the Republic of Uzbekistan, Tashkent, fax (3712) 44 26 61. Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent, fax (3712) 40 64 75. Translated from Khimiya Prirodnykh Soedinenii, No. 3, pp. 440–447, May–June, 1997.

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Burkhanova, N.D., Yugai, S.M., Khalikov, S.S. et al. Interaction of drugs with microcrystalline cellulose at the molecular and supermolecular levels. Chem Nat Compd 33, 340–346 (1997). https://doi.org/10.1007/BF02234892

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  • DOI: https://doi.org/10.1007/BF02234892

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